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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.

Synthetic “micro lungs” could take COVID-19 research to the next level

Scientists have developed stem-cell technology to mass-produce tissue cultures resembling our breathing organs. These tissues offer a powerful model in which to study how SARS-CoV-2 wreaks havoc in the lungs and to screen for new drugs.

The blood may hold clues to some of COVID-19’s most mysterious symptoms

COVID-19 causes a host of diverse complications, from lung inflammation to blood clots, heart failure, and brain fog. A team of scientists believes these attributes may have a single culprit—and that findings from research on Alzheimer’s disease might give them a leg up in finding it.

Rockefeller begins testing of new COVID-19 antibody drug in people

Patients in the clinical trial will receive two highly potent antibodies against SARS-CoV-2 discovered at the university. Designed to prevent people with early COVID-19 from developing severe disease, the treatment is urgently needed as hospitals continue to be inundated by repeated surges of infection, and mass vaccinations are still months away.

What Darwin never guessed 

Scientists have found that evolution isn’t always a one-way street toward specialization.

Scientists capture the moving parts of the portal to the cell’s nucleus

The proteins of the nuclear pore complex flip-flop rapidly between two orientations as they let cargo through.

Study of 50,000 people finds brown fat may protect against many diseases

People with brown fat tissue tend to burn calories more quickly, but do they also enjoy better health? Now the largest study of its kind shows that brown fat is indeed linked to reduced risk of heart disease, type 2 diabetes, and several other conditions.

Llamas immune to coronavirus, what zebrafish are thinking, and other memorable science stories of 2020 

This year's scientific endeavors included multiple attacks on SARS-CoV-2—and a lot more. Here are the most memorable science stories to come out of Rockefeller labs, from cracking the code behind specific skin cancer subtypes to understanding what goes on inside a fish brain.

As COVID-19 vaccines emerge, the search for antiviral drugs continues

Scientists are digging through drug libraries of 430,000 compounds, in pursuit of an antiviral drug that can stop the novel coronavirus in its tracks.

A mediocre mutator 

Scientists developed a method to safely examine the ability of SARS-CoV-2 to escape future drugs or vaccines by mutating. Their initial results are reassuring.

Royalty Pharma and Pablo and Almudena Legorreta Support Development of Antibody-Based COVID-19 Therapy at The Rockefeller University

Royalty Pharma and The Rockefeller University announced generous gifts totaling $5,760,000 from Royalty Pharma and Pablo and Almudena Legorreta.

Recent Awards and Honors

Junyue Cao

Junyue Cao wins Science & SciLifeLab Grand Prize For Young Scientists

November 19, 2020

Cao is recognized for his work using single-cell genomic methods to enable developmental mapping of entire organisms, described in an essay published in Science.
LLuciano Marraffini portrait

Luciano Marraffini awarded Max Planck-Humboldt Medal

October 14, 2020

Marraffini receives the award for his achievements studying CRISPR-Cas, a bacterial immune mechanism whose discovery led to modern gene-editing tools.
More awards and honors

Rockefeller in the News

The New York Times

Laboratory studies from Michel Nussenzweig and others of mutations circulating in South Africa suggest they may dodge some of the body’s immune responses.

The Wall Street Journal

Researchers are working on new antibody drugs that can be given with quick jabs in the arm, similar to flu shots. They would enable patients to get treated quickly after being diagnosed with Covid-19, said Michel C. Nussenzweig, an immunologist and professor at Rockefeller University in New York.

Nature News

Evidence from Jean-Laurent Casanova and others is growing that self-attacking ‘autoantibodies’ could be the key to understanding some of the worst cases of SARS-CoV-2 infection.

Seek magazine

Rockefeller’s flagship publication is interested not just in scientific results, but in the people, ideas, and conversations that ignite discovery. The latest issue takes us inside the response to the pandemic, where scientists are using every tool in the 21st century playbook to transform COVID-19 into a manageable disease. Also: Mosquito menace, The brain inside your gut, and Addiction then and now.


From this issue

 


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