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Structure of ion channel reveals how insects smell their way around the world

Researchers describe, for the first time, the structure of a smell-receptor protein common among insects. Its inner architecture illuminates how insects evolved to detect an amazing diversity of odors.

Researchers uncover molecular mechanisms of rare skin disease

Scientists describe a group of proteins that protect cells from a subtype of human papilloma virus. They also outline genetic mutations that make this virus unusually harmful in people with epidermodysplasia verruciformis, a rare skin condition.

Lack of a single molecule may indicate severe and treatment-resistant depression

Researchers find that a deficiency of acetyl-L-carnitine is associated with a particular subtype of depression. Individuals with very low levels of this molecule often have highly severe symptoms and don’t respond to traditional antidepressants.

Ant study sheds light on the evolution of workers and queens

A new study in ants identifies a peptide that plays an important role in regulating reproduction. This research illuminates a potential trajectory for the evolution of distinct social castes—workers and queens.

Giant neurons in the brain may play similarly giant role in awareness and cognition

Scientists find that certain neurons release nitric oxide onto nearby blood vessels, and potentially use this mechanism to control awareness in the brain.

Erich Jarvis receives grant from W.M. Keck foundation

With a new grant from the W.M. Keck foundation, the Jarvis Lab will further their research on the genes and neural circuits involved in speech production.

Monkey studies reveal possible origin of human speech

Scientists have long debated the evolutionary origins of human speech. New research reveals neural circuits in the brains of monkeys that may represent the source of our unique speech capabilities.

Scientists discover a mechanism of drug resistance in breast and ovarian cancer

A new study helps explain why certain cancers don't respond to treatment, and offers hope for overcoming this deadly resistance.

New faculty member studies the mechanics of development, challenging long-held assumptions

Earlier this month, developmental biologist Amy Shyer joined the Rockefeller community as an assistant professor. Shyer combines mechanical and molecular perspectives to better understand how patterns form and how tissues develop.

Three Rockefeller scientists promoted to professor

Sean Brady, Winrich Freiwald, and Luciano Marraffini have been promoted to professor. Respectively, these scientists have characterized previously unknown small molecules, provided insight into how the brain processes faces, and revolutionized gene editing.

Recent Awards and Honors

Elaine Fuchs elected fellow of the National Academy of Inventors

December 11, 2018

Fuchs, Rebecca C. Lancefield Professor and head of the Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, is honored for her pioneering study of the molecular mechanisms by which skin stem cells make and repair tissues and deviate in aging and cancer.

Portrait of David C. Gadsby

David C. Gadsby named a fellow of the American Association for the Advancement of Science

November 27, 2018

Gadsby, Patrick A. Gerschel Family Professor Emeritus, is recognized for his study of ion transport proteins in cell membranes, including the CFTR channel whose mutation causes cystic fibrosis.

More awards and honors

Rockefeller in the News

The New York Times

"It was beginning to look hopeless for obese people. Then, in 1995, Dr. Jeffrey Friedman of Rockefeller University discovered what looked like the equivalent of insulin for diabetes—a molecule he called leptin that is secreted by fat cells and tells the brain how much fat the body has."

Science

"Error-free genomes from a broad sampling of vertebrates will enable researchers 'to address questions not possible to [answer] before,' adds neuroscientist Erich Jarvis of The Rockefeller University in New York City, who leads G10K."

New York Times

By looking at which genes are activated in the brains of queens and workers of different ant species, Dr. [Daniel] Kronauer and his colleagues determined that a hormone called insulin-peptide 2, or ILP2, played the most important role.

 

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