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Small molecule from Kapoor lab is accepted as first Bridge Medicines drug candidate

A chemical inhibitor targeting basal cell carcinoma, originating from Tarun Kapoor’s lab, is graduating from the Tri-Institutional Therapeutics Discovery Institute into Bridge Medicines.

From infection-dodging stem cells, new tactics for research on viral disease

Among other superpowers, stem cells have a knack for fending off viruses like dengue and zika. Scientists have gained new insight into these curious defense strategies—knowledge they say could fuel the development of drugs against a range of diseases.

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Structural studies help explain how cancer cells resist chemotherapy

New research sheds light on how some cancer cells use molecular pumps to expel chemotherapy drugs before they have a chance to work.

Astrophysicist Kip Thorne to receive Rockefeller’s 2018 science writing prize

Thorne is recognized for his deft explanations that have drawn readers into the space-, time-, and mind-bending realm of Einstein’s ideas. The prize, which honors scientists as inspirational authors, will be presented on April 17.

What happens to a dying cell’s corpse? New findings illuminate an old problem

Scientists have discovered a curious way for cells to die. In studying it, they are learning about how remnants of diseased cells are normally chewed up and removed.

Scientists map the portal to the cell’s nucleus

The gateway to cellular headquarters has 552 components. A new map that shows how all these pieces fit together could help scientists study numerous diseases.

Scientists caution that a rare childhood liver cancer can spread to the brain

A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.

Molecular doorstop could be key to new tuberculosis drugs

In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease—and possibly others, as well.

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Building the machinery that makes proteins

Scientists have used cryo-electron microscopy to capture the very first snapshots of the large ribosomal subunit—part of the ribosome responsible for forging bonds between amino acids, the building blocks of proteins—coming together.

Molecule discovered in dirt could help against multi-resistant bacteria

In mining soil for natural drugs, scientists have discovered a brand-new antibiotic potent against many bacteria. They hope it could be used to treat infections that cannot be stopped with existing drugs.

Recent Awards and Honors

Shruti Naik portrait

Shruti Naik recognized on longlist for the Nature Research Award for Inspiring Science

July 26, 2018

A former Rockefeller postdoc, Naik is recognized for her outstanding work examining how environmental stimuli collaborate with genetic factors to control immunity in the skin.

Sohail Tavazoie portrait

Sohail Tavazoie named an Emerging Leader by the National Academy Medicine

July 19, 2018

Tavazoie was selected as an Emerging Leader in Health and Medicine for his leadership qualities and cutting-edge cancer research.

More awards and honors

Rockefeller in the News

New York Times

By looking at which genes are activated in the brains of queens and workers of different ant species, Dr. [Daniel] Kronauer and his colleagues determined that a hormone called insulin-peptide 2, or ILP2, played the most important role.

Scientific American

As [A. James] Hudspeth explored the neural mechanisms of hearing over the years, he developed a special appreciation for the intricate anatomy of the inner ear—an appreciation that transcends the laboratory. “I think we as scientists tend to underemphasize the aesthetic aspect of science,” he says.

Science

"'It is mind-blowing' that cells from such evolutionarily distant species can share these developmental instructions, says Ali Brivanlou, a stem cell biologist at The Rockefeller University in New York City and a senior author on the new study. The organizer 'has been conserved evolutionarily over hundreds of millions of years, so not seeing it would have been a surprise,' he says. But, 'There is something really emotional about looking that far back at human origin.'"

 

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Communications and Public Affairs

The Office of Communications and Public Affairs promotes and disseminates research news and other information about The Rockefeller University.