Lab experiments suggest that the new strains reported in Britain, South Africa, and Brazil may blunt the potency of the Pfizer and Moderna COVID-19 vaccines. This could mean that the vaccines will need updates as the virus mutates.
Victor Wilson, a neurophysiologist who traced the intricate neural mechanisms that govern our balance and posture, died on January 20 at the age of 92.
Scientists have developed stem-cell technology to mass-produce tissue cultures resembling our breathing organs. These tissues offer a powerful model in which to study how SARS-CoV-2 wreaks havoc in the lungs and to screen for new drugs.
The study participants continued to improve their antibodies months after initial infection, potentially due to exposure to remnants of the virus hidden in the gut.
COVID-19 causes a host of diverse complications, from lung inflammation to blood clots, heart failure, and brain fog. A team of scientists believes these attributes may have a single culprit—and that findings from research on Alzheimer’s disease might give them a leg up in finding it.
Patients in the clinical trial will receive two highly potent antibodies against SARS-CoV-2 discovered at the university. Designed to prevent people with early COVID-19 from developing severe disease, the treatment is urgently needed as hospitals continue to be inundated by repeated surges of inf...
People with brown fat tissue tend to burn calories more quickly, but do they also enjoy better health? Now the largest study of its kind shows that brown fat is indeed linked to reduced risk of heart disease, type 2 diabetes, and several other conditions.
This year's scientific endeavors included multiple attacks on SARS-CoV-2—and a lot more. Here are the most memorable science stories to come out of Rockefeller labs, from cracking the code behind specific skin cancer subtypes to understanding what goes on inside a fish brain.
Scientists developed a method to safely examine the ability of SARS-CoV-2 to escape future drugs or vaccines by mutating. Their initial results are reassuring.
The virus must hijack a more than a hundred human proteins to replicate inside a cell. One of them stands out because it is an absolute requirement for infection by four different coronaviruses as well as by viruses that cause Zika, yellow fever, and other diseases.
Rice was honored for research that contributed to a cure for hepatitis C. He accepted the Nobel medal and diploma at the Swedish Consulate in New York City.
Caskey, a clinician in the lab of Michel Nussenzweig, has spent the last decade working on clinical studies of experimental immune-based vaccines and therapies.
The $675 million Campaign for the Convergence of Science and Medicine, launched July 1, 2019, aims to fulfill the priorities identified in the university’s 2020-2024 strategic plan.
Unlike most humans, bats are naturally resistant to coronavirus infection. Researchers are now searching their genomes for clues that might explain why SARS-CoV-2 can cause devastating disease in our own species.
Researchers have found the first evidence that telomere shortening is not just a sign of aging, but a key component of the body's cancer prevention system.
Experiments in zebrafish are shining light onto a poorly understood process in which cells communicate mechanically, by pushing and pulling on each other.
Researchers have launched a tremendous race to understand the new virus and attack it from every angle. How they work and collaborate might never again be the same.
Only in sci-fi movies can a living cell be created from scratch. But a recent discovery suggests that this tantalizing feat might one day become possible in the real world.
New research suggests that our immune system may play an active role in shaping the digestive-tract flora, which is tightly linked to health and disease.
In a painstaking experiment, scientists suspended a single protein filament between two microscopic beads. Their results have shed light on an elusive process in which cells receive and respond to mechanical cues.
The novel compound, discovered in Jan L. Breslow’s lab and now licensed to Bridge Medicines, will be designed to treat immune-mediated diseases without harming the rest of the immune system.
Female mosquitoes are armed with syringe-like stylets that begin to pump furiously only in the presence of blood. Scientists are now studying the specific neurons that line the stylet, and asking what mosquitoes taste when they bite us.
Rice will receive the 2020 Nobel Prize in Physiology or Medicine for research that led to a cure for hepatitis C, a viral disease affecting 170 million people worldwide. His lab worked on the virus for three decades and became the first to produce a version of it that could be grown and studied i...
Joanne Chory, who pioneered the application of molecular genetics to plant biology and transformed our understanding of photosynthesis, will receive the prize in a virtual ceremony hosted by Rockefeller on October 22.
New research suggests that breast and lung tumors metastasize by hijacking a neural signaling pathway, potentially opening the door to better diagnostics and treatments.
With input from participating students and scientists who volunteer with RockEDU, a blended Summer Science Research Program for high-school students was developed. The result was a modified SSRP curriculum with five experiential research tracks, complete with lab supply kits that were mailed to s...
Scientists long believed they knew precisely which nooks of the brain control our ability for selective attention. Now, new findings are redrawing the maps.
A new molecular structure explains how cells hold an alarm-triggering protein captive during cell division, preventing cells from targeting their own DNA.
A growing number of studies find that microbes in the gut directly influence biological processes from bowel movements to behavior. New research reveals how they impact levels of glucose in the blood.
The lysosome is having a moment. More than 60 years after this bubble-shaped cell structure was first discovered, scientists have found that it is key to our ability to metabolize iron, and a potential target for new cancer drugs.
Over the next three years, the fund will augment the university's wide-ranging research initiatives aimed at alleviating the COVID-19 pandemic, and also support the its women scientists in their training and careers.
New research identifies a protein that blocks infection by SARS-CoV-2, the coronavirus that causes COVID-19, along with several other types. The findings could inform treatment strategies and help us better prepare for future outbreaks.
Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the di...
Molecular CRISPR-Cas systems, most commonly known for their usefulness as gene editing tools, are ancient defense mechanisms employed by bacteria against viruses. The discovery of a counteracting viral trick could inform scientists' efforts to develop future gene-editing technologies.
Scientists have outlined a molecular program by which serotonin reuptake inhibitors reshape the brain to alleviate depression. Their findings provide clues for how to make better and faster-acting versions of these drugs.
Cells—and the molecules inside them—are always on the move. They’re being tugged at, prodded, reshuffled. Behind these actions are tiny forces that, after decades of neglect, are emerging as the next big thing in biology.
Scientists hope to deploy antibodies in the quest to end COVID-19. A recent study moves them closer to accomplishing a key step: finding out if the virus may acquire resistance to antibody-based drugs or vaccines, and how to potent...
Scientists have found that a hormone tells the brain to dramatically restructure neurons embedded in fat tissue. Their work widens our understanding of how the body regulates its energy consumption, and how obesity might be treated in the future.
A genomics study has identified a previously unknown cell type whose blood levels tend to rise and fall in patients with rheumatoid arthritis. The findings could make it easier to manage the disease and help scientists understand its root causes.
For the men and women of Plant Operations, there really was no university closure. Even as most of the university’s labs shut down, those that remained still semi-operational required support.
According to this year’s CWTS Leiden Ranking of over 1100 universities from 65 countries, Rockefeller has the highest proportion of frequently cited scientific publications.
Scientists have used advanced technology to “micro-dissect” the first brain cells to perish in Alzheimer’s disease. The result is a short list of genes that could represent new drug targets.
The Aedes aegypti genome might hold clues for developing the most effective repellants yet—including ones that make the mosquito unable to smell us, or less motivated to seek us out.
The CFC’s team has had to pivot quickly to create new online programming to support their young charges and provide age appropriate education and enrichment—and a measure of continuity.
