Skip to main content
!
Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
!
Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
!
Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
>

New molecular diagnostics test could help guide lupus treatments

A tool that detects glitches in gene expression could help doctors tailor treatments for lupus-related kidney damage.

Rockefeller tops global ranking of research excellence

An extensive international ranking of research institutions by U-Multirank gave Rockefeller top scores in several categories related to scientific impact and knowledge transfer.

>

New research shows that mosquitoes sense repellent through their legs

Scientists made the surprising discovery that the insects’ displeasure for touching DEET, the active ingredient in many repellents, helps prevent bites.

Small brains, big decisions 

Life is full of binary choices, even for small animals like fruit flies. With new technologies, scientists can now dissect the mechanisms of decision making in the simplest of brains, at the levels of individual molecules, cells, and networks.

To curb infection, bacteria direct their defenses against themselves

To fight off invading viruses, bacteria have evolved a slew of creative defense tactics. New research shows that in some cases, microbes go to great lengths to keep an infection from spreading, even destroying bits of their own genetic material.

New compounds could be used to treat autoimmune disorders

In autoimmune disorders, the body’s defense system erroneously attacks normal cells, leading to serious health problems. Researchers have developed new molecules that potentially could be used to treat many of these conditions.

New study reveals gut segments organized by function, and opportunities for better drug design

New findings provide insights about how the intestine maximizes nutrient uptake, while at the same time protecting the body from potentially dangerous microbes.

An accreditation renewal, and the campus-wide endeavor to ensure continued safeguarding of research participants

Rockefeller's reaccreditation from the Association for the Accreditation of Human Research Protection Programs marks the end of an extensive application process. The AAHRPP sets the gold standard in safeguarding volunteers participating in clinical research.

A new sculpture, donated by Torsten N. Wiesel, is perched in front of Flexner Hall

The cast-iron parrot is an architectural ornament from the late 19th or early 20th century.

Cellular rivalry promotes healthy skin development

Scientists have discovered a curious phenomenon taking place in mouse skin: cells compete with one another for the chance to develop into mature tissue. The findings indicate that this antagonism is key to creating healthy skin.

>

Researchers find genetic link to tuberculosis

Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.

>

Study explores genetic differences among people’s gut microbes, and their health consequences

Scientists have found that small genetic differences can cause the same gut microbe to behave differently in different people, and affect the overall health of their human hosts.

Research on repetitive worm behavior may have implications for understanding human disease

Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.

Jue Chen and Luciano Marraffini elected to National Academy of Sciences

Election to the National Academy of Sciences is one of the most prestigious honors a scientist can receive; including Chen and Marraffini, the number of current Rockefeller scientists who are members of the elite organization stands at 38, or nearly half the faculty.

Drugs from dirt 

Therapeutics has gone underground. From one bag of soil, chemists can now procure millions of microbial molecules. Any one could be tomorrow’s lifesaving medicine.

Study pinpoints what causes relapse after cancer immunotherapy

In many cancer patients who have been treated with immunotherapy, the tumor comes back. New research identifies the cells responsible for thwarting the treatment and offers new insights into how they do it.

>

Gene-editing technique opens door for HIV vaccine

Researchers successfully modified immune cells to produce antibodies that fight HIV. This strategy could eventually be used to develop a vaccine against the virus, among other conditions.

Rockefeller creativity on display at the 21st annual employee art show

This year’s show featured portraiture, travel photography, collage, and other mediums.

Celebrating and remembering Paul Greengard, a pioneering neuroscientist and Nobel laureate

Greengard revolutionized our understanding of how brain cells communicate with each other and contributed to major advances in the treatment of a wide range of neurological and psychiatric diseases. He died April 13 at the age of 93.

New microscopy technique peers deep into the brain

Using new imaging technology, researchers can now record the activity of large populations of brain cells with unprecedented speed, and at new depths.

New hope for treating a childhood brain cancer

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.

New approach to treating gastrointestinal disease patches up leaky intestines

Researchers have discovered a new compound that helps fortify the intestine's inner lining, which becomes porous in inflammatory bowel diseases.  

Scientists find brain mechanism that naturally combats overeating

Studying a brain region involved in memory, researchers discovered a set of neurons that help mice control their appetite.

>

New tool allows scientists to catch elusive protein in action

Scientists still have a lot to learn about the processes that trigger cell division, partly because they happen so quickly. A new chemical probe will make it possible to capture the workings of one of the key players.

Physician-writer Siddhartha Mukherjee will be awarded the 2019 Lewis Thomas Prize

The author of The Emperor of all Maladies, a best-selling book about cancer, will be presented with Rockefeller’s science writing award at a free, public ceremony on Rockefeller's campus next month.

>

Researchers discover a common link among diverse cancer types

Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.

The face-recognition puzzle 

For the brain, seeing a face is very different from seeing a teacup. In studying a mysterious ailment, face blindness, scientists are getting a rare glimpse into the biology of the mind.

Aaron Diamond AIDS Research Center will end 23-year affiliation with Rockefeller

A move to Columbia University will provide a new home for ADARC, which for many years has occupied laboratories in a city-owned building on First Avenue.

Rockefeller reaches key milestone in River Campus project

The temporary certificate of occupancy from the New York City Department of Buildings is a close-to-last step in the expansion of the university’s campus over the FDR Drive.

David C. Gadsby, who studied electrical impulses in cells, dies

Gadsby, who passed away Saturday at age 71, was best known for his studies determining the mechanisms by which charged particles called ions move across cell membranes.

>

Scientists find new clues about how the body stores fat

Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.

Scientists identify genetic factors that may cause some people to become obese

New research on leptin, a hormone that regulates appetite, reveals a previously unknown mechanism that may be responsible for at least 10 percent of obesity cases. The findings could help identify individuals with treatable forms of the condition.

Inside the brains of hungry worms, researchers find clues about how they hunt

When looking for food, the roundworm C. elegans searches the same area for up to 20 minutes before trying its luck at more distant locales. New research on the worm’s brain explains how this behavior arises at the level of molecules and cells.

The long-neglected culprit of Alzheimer's 

Despite decades of study, we know surprisingly little about why neurons fail and memories fade. One researcher is finding clues where few others have looked—in the brain’s blood chemistry.

Fall search for new faculty has yielded 10 finalists

The annual “open search” process for tenure-track faculty draws on the expertise of the entire university community.

Researchers discover a weakness in a rare cancer that could be exploited with drugs

Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.

New online resource brings science outreach to a broader audience

With the launch of a new website, RockEDU Online, more resources are now available for learners, educators, and scientists everywhere.

New findings could make mosquitoes more satisfied—and safer to be around

Scientists have learned new tricks that could be useful in preventing mosquito-borne illnesses such as Zika and yellow fever. A new study shows that some appetite-reducing drugs can curtail the insects’ impulse to feed on warm-blooded hosts.

Lysin therapy offers new hope for fighting drug-resistant bacteria

Increasingly, bacteria do not succumb to antibiotics. Rockefeller researchers have developed a new class of antimicrobial drug, lysin, with one compound showing promising results in a clinical trial—suggesting that an alternative to antibiotics may be on the horizon.

Daniel Kronauer discusses “The Social Lives of Ants” at this year’s Talking science event

More than 350 high school students from across the tri-state area attended this year’s event where Kronauer shared how ants can help answer questions about the principles that govern life.

An end in sight 

Medical science is holding its breath. For decades, the most it could do for people with HIV was to prevent them from dying of AIDS. Now, new therapies are raising hopes for something more: a world in which the virus will no longer cause suffering or fear.

>

In simple bacteria, scientists find new evidence of complex immunity

Bacteria use a multifaceted immune response to get rid of invading DNA. In a new study, researchers identify an enzyme that can destroy foreign genetic material capable of evading a microbe’s first line of defense.

Tri-institutional symposium inspires young scientists to get involved in policy

Over 230 attendees from across the country came to campus to learn about a range of topics, such as the federal budget, international science diplomacy, science advocacy, science communication, and careers in science policy.

Jeffrey M. Friedman to receive the 2019 Wolf Prize in Medicine

Friedman receives the award for his discovery of leptin, a hormone that modulates food intake and energy expenditure.

>

Enzyme structure reveals how DNA is opened up for transcription

DNA’s two strands must be separated before its code can be read, or transcribed. By studying the structure of the enzyme RNA polymerase, researchers have elucidated how DNA unwinds and becomes legible.

Electronic engineer Larry Eisenberg, who helped develop the modern pacemaker, dies at 99

In addition to his work at Rockefeller, Eisenberg was a prolific writer of science fiction and limericks.

Attallah Kappas, who led studies of newborn jaundice, dies at 92

Attallah Kappas, professor emeritus at The Rockefeller University and physician-in-chief emeritus at The Rockefeller University Hospital, died December 18, 2018 at the age of 92. Kappas was a leading authority in diseases related to liver function and metabolism and in the development of diagnost...

Study identifies genetic mutation responsible for tuberculosis vulnerability

Scientists discovered a genetic variant that greatly increases a person’s likelihood of developing tuberculosis. Their research elucidates how this mutation affects the immune system, and points to a possible treatment for people with the disease.

Year in review: 10 science stories to remember

Rockefeller researchers accomplished a lot this year. We look back at 10 of the most exciting science stories of 2018.

Caspary reverberates with the sound of the Music and Medicine Orchestra

On a recent wintry evening, over 400 people took their seats in Caspary Auditorium. Scientists were center stage, but there wasn’t any lecturing. Instead, there was music.

Rockefeller scientists tell their stories in new oral history project

Interviews with some of the university’s most prominent researchers reveal the stories behind the science, and the humans underneath the lab coats.

New strategic plan will outline university priorities over five-year term

President Rick Lifton has established a committee to guide the strategic planning process. It will be informed by presentations from administrative departments as well as input from the community at large.

Study explains how geckos gracefully gallop on water

Geckos are amazingly agile. In addition to running across land and up trees, the animals can prance across the surface of water. A new study reveals how they do it.

Seek magazine is now available online

A new digital edition makes Rockefeller’s award-winning publication available to readers everywhere.

Shape-shifting protein protects bacteria from invaders

Researchers have discovered how bacteria manage to destroy enemy DNA, while keeping their own genetic material safe.

First mapping of cells in the early human placenta to advance research on problem pregnancies

Scientists have made the first comprehensive inventory of cells present in the human placenta of the first trimester, a stage when many pregnancy complications are thought to arise. The findings could fuel new research on conditions such as preeclampsia and pre-term birth.

New method for studying gene expression could improve understanding of brain disease

By analyzing gene expression patterns, researchers have identified previously unknown distinctions between mouse and human neurons. They have also developed a new way to track cellular changes associated with brain disorders.

“Discoveries are delicate things”: What a century-old war can teach us about science today

In the 1910s, Rockefeller biochemist Israel Kleiner came close to discovering insulin, but missed his opportunity to find a much-needed treatment for diabetes. In a recent Harper’s Magazine essayneuroscientist Jeffrey M. Friedman explores the factors that set back Kleiner's wo...

Mosquito genome opens new avenues for reducing bug-borne disease

Researchers have assembled a new and improved DNA catalogue for the mosquito Aedes aegypti. This tool will help researchers understand the insect’s biology, and may lead to new strategies for preventing diseases like Zika and dengue.

Fundraising campaign surpasses goal two years ahead of schedule

Launched in 2011, the university’s Campaign for Transforming Biomedicine has raised $1.059 billion as of September 30 this year.