Scientists are learning how tumor cells’ nutritional needs differ from those of normal cells. Will their work help
launch the next genre of cancer therapies?
For some unlucky people, a bout of intestinal distress like traveler’s diarrhea leads to irritable bowel syndrome. Recent discoveries have given scientists a better idea of how this happens, and potential leads for new treatments.
A pioneer in neuroendocrinology, McEwen’s work on how the brain changes throughout life has profound implications for public health. He died on January 2, at age 81.
Scientists find a new brain area in control of our attention skills, raising new questions in what has long been considered a settled scientific field.
To scientists' surprise, the immune system develops its response to each virus variant mostly from scratch, instead of building on what it has already learned.
Researchers have identified a set of biological factors in mice that seem to determine one's ability to bounce back from a traumatic event, and provide preliminary evidence that a naturally-occurring substance may help boost resiliency in the face of stressful situations.
Protein clumps are routinely found in the brains of patients with neurodegenerative diseases. Now researchers find a link between this buildup and the intracellular movement of proteasomes, molecular machines tasked with degrading protein waste inside cells.
Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.
A new study finds that neurons affected in Parkinson’s disease can shut down without fully dying, allowing them to also switch off neighboring cells. The findings might give scientists a better understanding of how the condition wreaks havoc in the brain, as well as ideas for new treatments.
To grow new hair, stem cells throughout the skin must work in sync. Researchers have discovered the molecular communication tool, part of the lymphatic system, that the cells use to synchronize their activities.
Zhuang, who pioneered the development of super-resolution and genome-scale imaging techniques, will be given the prize during a ceremony on the Rockefeller campus on November 19.
The human papilloma virus is usually kept in check by the immune system, but scientists identified a genetic variant that makes some infected children prone to developing warts in the throat.
Allis, whose pioneering research established that enzymes that modify histone proteins, which package DNA in the nucleus, regulate gene expression, has been elected to the National Academy of Medicine.
An expert on ant biology, Kronauer found himself in the right place at the right time to capture a cathedral-shaped bivouac, or ants’ nest, in Costa Rica. The photo is now part of an international exhibit by the prestigious Wildlife Photographer of the Year competition.
In studying cell division, scientists happened upon a new way of understanding how a chemotherapy compound works. The findings could make it possible to predict which patients are most likely to benefit from the drug.
Scientists have found that many receptors with high potential for drug discovery take a different configuration inside the body than in the test tube. The findings could explain why some promising drugs fail in clinical trials, and potentially open doors to new drug-development approaches.
Even the most routine scientific experiment may come with a hefty environmental footprint. Here are several best practices to reduce waste, save energy, and cultivate more planet-friendly lab habits.
Ruta, who investigates how the brain is modified by experience, has received a MacArthur Fellowship, an award intended to encourage people of outstanding talent to pursue their own creative, intellectual, and professional inclinations.
Using a new technique to study brain development, scientists were able to trace the causes of Huntington's back to early developmental stages when the brain has only just begun to form.
The university’s Campaign for Transforming Biomedicine—which raised $1.17 billion over eight years—closed this summer with a bang: three significant capstone gifts, made in the campaign’s final months, to directly support Rockefeller science.
Memories are inherently shifty. A neuroscientist with a new lab of her own, Rajasethupathy likens the brain’s memory function to Wikipedia—always evolving, occasionally unreliable.
A common birthplace of new genes, the male testes are a hotspot for biological innovation. Within these organs, scientists have found a trove of virgin genetic sequences—and a better understanding of how evolution moves forward.
Researchers have shown that antibodies against Zika might be involved in causing birth defects in babies born to infected women. The findings might provide important caveats for the development of a vaccine.
Cell division is critical to creating and sustaining life. It’s also incredibly difficult to study. Now, advanced technology is enabling researchers to take their understanding of this process to the next level.
With science constantly advancing, ethical boundaries need regular recalibration. It’s a task scientists cannot do alone, says Brivanlou; all of society needs to engage.
For the brain to function smoothly, its cells must carefully regulate which proteins are produced and when. By studying gene regulation, researchers are now shedding light on complex brain conditions like autism and stroke.
Navigating fruit flies do not have the luxury of GPS, but they do have a kind of neural compass. In a new study, researchers found that the animals decide which way to turn by comparing this internal compass needle to a fixed goal.
Drugs known as potentiators alleviate some symptoms of cystic fibrosis. Researchers recently figured out how these compounds work—a finding that may lead to better drugs that patients can more easily afford.
A mathematical physicist, Feigenbaum's groundbreaking work on deterministic chaos influenced fields ranging from cardiology to cartography. He died on June 30, at age 74.
Researchers have created a new 3D model of human embryonic tissue that promises to shed light on critical components of development—including processes that go awry during pregnancy complications.
Scientists have found a group of brain cells that influence body mass in two ways, by controlling how much we eat as well as how much energy we burn. The findings could lead to new drugs to help people shed weight.
Animals learn the hard way which sights, sounds, and smells are relevant to survival. New research in flies shows that the timing of these cues plays an important role in how mental associations arise, and elucidates brain pathways involved in this process.
Deadly and elusive, M. tuberculosis has ravaged the world for centuries. Armed with new technologies to study the pathogen, scientists may finally be poised to intervene.
After four years of construction, the Stavros Niarchos Foundation–David Rockefeller River Campus has opened its doors to the community, with several labs already installed in its new research building.
An extensive international ranking of research institutions by U-Multirank gave Rockefeller top scores in several categories related to scientific impact and knowledge transfer.
Scientists made the surprising discovery that the insects’ displeasure for touching DEET, the active ingredient in many repellents, helps prevent bites.
Life is full of binary choices, even for small animals like fruit flies. With new technologies, scientists can now dissect the mechanisms of decision making in the simplest of brains, at the levels of individual molecules, cells, and networks.
To fight off invading viruses, bacteria have evolved a slew of creative defense tactics. New research shows that in some cases, microbes go to great lengths to keep an infection from spreading, even destroying bits of their own genetic material.
In autoimmune disorders, the body’s defense system erroneously attacks normal cells, leading to serious health problems. Researchers have developed new molecules that potentially could be used to treat many of these conditions.
New findings provide insights about how the intestine maximizes nutrient uptake, while at the same time protecting the body from potentially dangerous microbes.
Rockefeller's reaccreditation from the Association for the Accreditation of Human Research Protection Programs marks the end of an extensive application process. The AAHRPP sets the gold standard in safeguarding volunteers participating in clinical research.
Scientists have discovered a curious phenomenon taking place in mouse skin: cells compete with one another for the chance to develop into mature tissue. The findings indicate that this antagonism is key to creating healthy skin.
Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.
Scientists have found that small genetic differences can cause the same gut microbe to behave differently in different people, and affect the overall health of their human hosts.
Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.
Election to the National Academy of Sciences is one of the most prestigious honors a scientist can receive; including Chen and Marraffini, the number of current Rockefeller scientists who are members of the elite organization stands at 38, or nearly half the faculty.
