Scientists have discovered a curious phenomenon taking place in mouse skin: cells compete with one another for the chance to develop into mature tissue. The findings indicate that this antagonism is key to creating healthy skin.
Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.
Scientists have found that small genetic differences can cause the same gut microbe to behave differently in different people, and affect the overall health of their human hosts.
Studying microscopic worms, Rockefeller scientists have identified a brain circuit that drives repetitive behavior—providing potential clues for understanding some human psychiatric conditions.
Election to the National Academy of Sciences is one of the most prestigious honors a scientist can receive; including Chen and Marraffini, the number of current Rockefeller scientists who are members of the elite organization stands at 38, or nearly half the faculty.
Therapeutics has gone underground. From one bag of soil, chemists can now procure millions of microbial molecules. Any one could be tomorrow’s lifesaving medicine.
In many cancer patients who have been treated with immunotherapy, the tumor comes back. New research identifies the cells responsible for thwarting the treatment and offers new insights into how they do it.
Researchers successfully modified immune cells to produce antibodies that fight HIV. This strategy could eventually be used to develop a vaccine against the virus, among other conditions.
Greengard revolutionized our understanding of how brain cells communicate with each other and contributed to major advances in the treatment of a wide range of neurological and psychiatric diseases. He died April 13 at the age of 93.
Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.
Scientists still have a lot to learn about the processes that trigger cell division, partly because they happen so quickly. A new chemical probe will make it possible to capture the workings of one of the key players.
The author of The Emperor of all Maladies, a best-selling book about cancer, will be presented with Rockefeller’s science writing award at a free, public ceremony on Rockefeller's campus next month.
Some cancers have been traced to changes in histones, proteins responsible for packaging DNA and regulating genes. Now, research from Rockefeller scientists shows that, among tumors, mutations to these proteins are a lot more common than previously suspected.
For the brain, seeing a face is very different from seeing a teacup. In studying a mysterious ailment, face blindness, scientists are getting a rare glimpse into the biology of the mind.
A move to Columbia University will provide a new home for ADARC, which for many years has occupied laboratories in a city-owned building on First Avenue.
The temporary certificate of occupancy from the New York City Department of Buildings is a close-to-last step in the expansion of the university’s campus over the FDR Drive.
Gadsby, who passed away Saturday at age 71, was best known for his studies determining the mechanisms by which charged particles called ions move across cell membranes.
Scientists discovered a protein that plays a crucial role in regulating fatty acids, the molecules that make up body fat. This research could lead to new options for treating people with diseases associated with fatty acid buildup.
New research on leptin, a hormone that regulates appetite, reveals a previously unknown mechanism that may be responsible for at least 10 percent of obesity cases. The findings could help identify individuals with treatable forms of the condition.
When looking for food, the roundworm C. elegans searches the same area for up to 20 minutes before trying its luck at more distant locales. New research on the worm’s brain explains how this behavior arises at the level of molecules and cells.
Despite decades of study, we know surprisingly little about why neurons fail and memories fade. One researcher is finding clues where few others have looked—in the brain’s blood chemistry.
Researchers have identified a rare type of cancer cell that cannot make cholesterol, a key nutrient. By targeting this deficiency, scientists may be able to develop new strategies for treating the disease.
Scientists have learned new tricks that could be useful in preventing mosquito-borne illnesses such as Zika and yellow fever. A new study shows that some appetite-reducing drugs can curtail the insects’ impulse to feed on warm-blooded hosts.
Increasingly, bacteria do not succumb to antibiotics. Rockefeller researchers have developed a new class of antimicrobial drug, lysin, with one compound showing promising results in a clinical trial—suggesting that an alternative to antibiotics may be on the horizon.
More than 350 high school students from across the tri-state area attended this year’s event where Kronauer shared how ants can help answer questions about the principles that govern life.
Medical science is holding its breath. For decades, the most it could do for people with HIV was to prevent them from dying of AIDS. Now, new therapies are raising hopes for something more: a world in which the virus will no longer cause suffering or fear.
Bacteria use a multifaceted immune response to get rid of invading DNA. In a new study, researchers identify an enzyme that can destroy foreign genetic material capable of evading a microbe’s first line of defense.
Over 230 attendees from across the country came to campus to learn about a range of topics, such as the federal budget, international science diplomacy, science advocacy, science communication, and careers in science policy.
DNA’s two strands must be separated before its code can be read, or transcribed. By studying the structure of the enzyme RNA polymerase, researchers have elucidated how DNA unwinds and becomes legible.
Attallah Kappas, professor emeritus at The Rockefeller University and physician-in-chief emeritus at The Rockefeller University Hospital, died December 18, 2018 at the age of 92. Kappas was a leading authority in diseases related to liver function and metabolism and in the development of diagnost...
Scientists discovered a genetic variant that greatly increases a person’s likelihood of developing tuberculosis. Their research elucidates how this mutation affects the immune system, and points to a possible treatment for people with the disease.
On a recent wintry evening, over 400 people took their seats in Caspary Auditorium. Scientists were center stage, but there wasn’t any lecturing. Instead, there was music.
President Rick Lifton has established a committee to guide the strategic planning process. It will be informed by presentations from administrative departments as well as input from the community at large.
Geckos are amazingly agile. In addition to running across land and up trees, the animals can prance across the surface of water. A new study reveals how they do it.
Scientists have made the first comprehensive inventory of cells present in the human placenta of the first trimester, a stage when many pregnancy complications are thought to arise. The findings could fuel new research on conditions such as preeclampsia and pre-term birth.
By analyzing gene expression patterns, researchers have identified previously unknown distinctions between mouse and human neurons. They have also developed a new way to track cellular changes associated with brain disorders.
In the 1910s, Rockefeller biochemist Israel Kleiner came close to discovering insulin, but missed his opportunity to find a much-needed treatment for diabetes. In a recent Harper’s Magazine essay, neuroscientist Jeffrey M. Friedman explores the factors that set back Kleiner's wo...
Researchers have assembled a new and improved DNA catalogue for the mosquito Aedes aegypti. This tool will help researchers understand the insect’s biology, and may lead to new strategies for preventing diseases like Zika and dengue.
A new study shows that embryonic cells retain a memory of the chemical signals to which they are exposed. Without these memories, cells fail organize into distinct tissue types.
Analyzing soil samples from across the country, researchers have identified an antibiotic capable of treating strains of tuberculosis that do not respond to existing therapies.
Rockefeller hosts historical and architectural tours as part of Open House New York, a citywide festival that puts on display buildings and spaces not usually open to the public.
The Precision Instrumentation Technologies facility has been outfitted with a CNC milling machine, a high-performance instrument that will help Rockefeller engineers custom-make scientific devices.
Using a unique mouse model, Rockefeller scientists have developed a new strategy in cancer immunotherapy that is more safe and effective than other treatments of its kind.
As you encounter new experiences and form new memories, your brain changes. Now, researchers show that some of these change occur in a brain region devoted to visual perception.
