A class of ineffective immune cells may be driving Alzheimer’s disease, a finding that could both explain why APOE4 gene increases the risk of the disease and why a new drug can impact it.

LINE-1 is associated with disease and aging. The Rout lab has uncloaked the core of its key protein, pointing the way towards therapeutic targets.

She was known by her colleagues for both her committed professionalism and her generous spirit.

Luciano Marraffini’s research helped lay the groundwork for the newly FDA-approved CRISPR-based therapy for sickle cell anemia. He reflects on how we got here—and where the science is going next.

It also reduces the cost of a million single-cell transcriptomes from $10,000 to $700—and the time necessary down to about a day.

By focusing on the emergent features of cell collectives, instead of individual cells, scientists forge a new path for understanding how organs develop their architecture.   

From plumbing the depths of wound repair to tackling how songbirds solve problems, here are some fascinating discoveries that came out of Rockefeller in 2023.

Carlo Yuvienco, the inaugural director of the university’s new Ford Center Incubator, on how the new space will help translate research breakthroughs into market-ready biomedical innovations.

Mojsov’s research directly led to blockbuster drugs like Ozempic and Wegovy. She talks about the long quest for proper credit and lessons that can be learned from her experience.

Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.

“I believe this is going to be a very fruitful find. Every time people have studied nutrient sensing, we’ve learned a lot about biology, and many drugs have been developed as a result.”

The low-cost multi-cancer detector can pick up the presence of a telltale protein in a tiny amount of blood in less than two hours.

New research suggests that the long sought-after environmental trigger for MS is a toxin produced by certain C. perfringens bacteria.

Why do our bodies not only fail to learn from prior dengue infection but also become more vulnerable to it as a result? New research pinpoints a subgroup of antibodies that may be to blame.

The new research hub will engineer immune cells for early disease prevention, detection, and treatment.

The use of images in scientific papers is more popular than ever, but there have been no common standards for their publication—until now.

Science Saturday brings hundreds of kids back to campus for the first time since 2019.

The novel technique may offer panoramic view into the mechanisms of many diseases and the enigma of aging.

Steve Bonilla joined Rockefeller as an assistant professor on October 1, 2023.

Jan and Marder, who have both made fundamental contributions to neurobiology, were presented with the award in a ceremony on The Rockefeller University campus on September 20.

The better a songbird is at working its way around obstacles to retrieve a snack, the more complex its vocal learning ability will be.

As with many cutting-edge therapies, we know more about the drug's effectiveness than we do about how it actually operates. A new study reveals a possible mechanism for its impact on patients.

Murray discusses developing strategies and programming grounded in the belief that a true community draws strength from its individuals.

Patients with a specific cocktail of COVID exposure had the highest level of antibodies against SARS-CoV-2 and its variants, which also provided a strong immunological shield for their babies.

Sponsored by the Office for Diversity, Equity, and Inclusion, the event brought together land stewards from across the city in an effort to make soil science more accessible to the local community.

One clever way to observe the neural activity of Drosophilae: build them a custom fly treadmill and tempt them with the tangy perfume of apple cider vinegar.

In skin, some aberrant adult epidermal stem cells turn on SOX9, kickstarting a process that ultimately activates cancer genes.

Birsoy is honored for groundbreaking research uncovering metabolic weaknesses of diseased cells, such as cancer, while shedding light on debilitating mitochondrial diseases and rare genetic disorders.

With 40% of encephalitis cases now explained by an autoimmune deficiency, West Nile virus "is by far the best understood human infectious disease in the world. It’s stunning.”

Gregory Alushin reveals fundamental truths about cellular biomechanics by studying how the wiggly protein strands known as actin filaments bend and flex, crisscross each other, and have tugs of war.