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Joanne Chory wins the 2020 Pearl Meister Greengard Prize

Joanne Chory, who pioneered the application of molecular genetics to plant biology and transformed our understanding of photosynthesis, will receive the prize in a virtual ceremony hosted by Rockefeller on October 22.

Cancer cells use nerve-cell tricks to spread from one organ to the next

New research suggests that breast and lung tumors metastasize by hijacking a neural signaling pathway, potentially opening the door to better diagnostics and treatments.

A revised map of where working memory resides in the brain

Findings from genetically diverse mice challenge long-held assumptions about how the brain is able to briefly hold onto important information.

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

The findings explain why some people are so vulnerable to the infection, and suggest new avenues for treatment.

When the city locked down, RockEDU moved the lab bench to the kitchen table

With input from participating students and scientists who volunteer with RockEDU, a blended Summer Science Research Program for high-school students was developed. The result was a modified SSRP curriculum with five experiential research tracks, complete with lab supply kits that were mailed to s...

Attention needs more attention 

Scientists long believed they knew precisely which nooks of the brain control our ability for selective attention. Now, new findings are redrawing the maps.

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How dividing cells avoid setting off false virus alarms

A new molecular structure explains how cells hold an alarm-triggering protein captive during cell division, preventing cells from targeting their own DNA.

Microbes in the gut may influence metabolism

A growing number of studies find that microbes in the gut directly influence biological processes from bowel movements to behavior. New research reveals how they impact levels of glucose in the blood.

Return of the cytonaut 

The lysosome is having a moment. More than 60 years after this bubble-shaped cell structure was first discovered, scientists have found that it is key to our ability to metabolize iron, and a potential target for new cancer drugs.

Bulgari Corporation to support Rockefeller's COVID-19 research and women scientists

Over the next three years, the fund will augment the university's wide-ranging research initiatives aimed at alleviating the COVID-19 pandemic, and also support the its women scientists in their training and careers.

Heritable genome editing technology is not yet ready for clinical use, concludes an international commission co-chaired by President Lifton

A range of scientific and medical issues have yet to be addressed, the committee determined, and many ethical, moral, and societal concerns remain.

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Scientists uncover antiviral protein that blocks coronavirus infection

New research identifies a protein that blocks infection by SARS-CoV-2, the coronavirus that causes COVID-19, along with several other types. The findings could inform treatment strategies and help us better prepare for future outbreaks.

How mechanical forces nudge tumors toward malignancy

Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the di...

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Newly discovered anti-CRISPR protein gives viruses a leg up against bacteria

Molecular CRISPR-Cas systems, most commonly known for their usefulness as gene editing tools, are ancient defense mechanisms employed by bacteria against viruses. The discovery of a counteracting viral trick could inform scientists' efforts to develop future gene-editing technologies.

Study uncovers the molecular events by which popular antidepressants work

Scientists have outlined a molecular program by which serotonin reuptake inhibitors reshape the brain to alleviate depression. Their findings provide clues for how to make better and faster-acting versions of these drugs.

Life's inner mechanics 

Cells—and the molecules inside them—are always on the move. They’re being tugged at, prodded, reshuffled. Behind these actions are tiny forces that, after decades of neglect, are emerging as the next big thing in biology.

Will SARS-CoV-2 escape future drugs by mutating? The answer may be a nuanced “no.”

Scientists hope to deploy antibodies in the quest to end COVID-19. A recent study moves them closer to accomplishing a key step: finding out if the virus may acquire resistance to antibody-based drugs or vaccines, and how to potent...


A never-before-seen image of the coronavirus copy machine

The high-resolution 3D image can speed COVID-19 drug discovery.

How toothless mock viruses could advance research on COVID-19

Scientists have engineered four viruses resembling SARS-CoV-2 to enable faster and safer research on vaccines and treatments.

Bacteria in the gut have a direct line to the brain

Scientists find that microbes inside the intestines can control the activities of neurons connecting the gut and brain.

Amid the rush for COVID-19 drugs, a case for the helicase

The enzyme is essential for the virus to replicate itself inside our cells. Scientists already have ideas for how to block it.

How neurons in body fat grow to boost calorie-burning capacity

Scientists have found that a hormone tells the brain to dramatically restructure neurons embedded in fat tissue.  Their work widens our understanding of how the body regulates its energy consumption, and how obesity might be treated in the future.

Becoming a Scientist: Jeanne Garbarino 

Meet Jeanne Garbarino, the scientist whose job it is to get teens out of their textbooks and into the lab.

Novel cells might act as a warning sign for rheumatoid arthritis flares

A genomics study has identified a previously unknown cell type whose blood levels tend to rise and fall in patients with rheumatoid arthritis. The findings could make it easier to manage the disease and help scientists understand its root causes.

Interview: Mary Jeanne Kreek 

Thousands of years after humans discovered opioids, we’re just beginning to understand how these substances warp the brain and change behaviors.

How Plant Operations maintained essential university functions during shutdown

For the men and women of Plant Operations, there really was no university closure. Even as most of the university’s labs shut down, those that remained still semi-operational required support.

Rockefeller tops international ranking of research impact

According to this year’s CWTS Leiden Ranking of over 1100 universities from 65 countries, Rockefeller has the highest proportion of frequently cited scientific publications.

Why memory-forming neurons are vulnerable to Alzheimer's

Scientists have used advanced technology to “micro-dissect” the first brain cells to perish in Alzheimer’s disease. The result is a short list of genes that could represent new drug targets.

If humans could hide 

The Aedes aegypti genome might hold clues for developing the most effective repellants yet—including ones that make the mosquito unable to smell us, or less motivated to seek us out.

How an adapting Child and Family Center supports the littlest learners in the pandemic

The CFC’s team has had to pivot quickly to create new online programming to support their young charges and provide age appropriate education and enrichment—and a measure of continuity.