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A recent study reveals how the nucleolus gives rise to ribosomes—and how scientists can use that knowledge to reshape the nucleolus itself.

After nearly a decade of cataloguing evolutionarily young genes, complementary studies are the first to demonstrate how they are regulated and expressed.

Scientists discovered an identical neural circuit that operates differently in male and female mice.

Research shows low levels of the amino acid serine trigger a process that turns hair follicle stem cells into skin repair specialists—and that diet may have a role to play.

New research demonstrates that a previously published structure and mechanism for RNA capping at work in coronaviruses is incorrect, with potentially sweeping implications for the quest to develop drugs targeting these pathogens.

The Vertebrate Genomes Project has set its sights on creating high-quality reference genomes to help answer some of science’s biggest questions.

With support from students and city policy, the university’s popular residential composting program is helping turn food waste into community benefit

New research suggests that amyloid-beta (Aβ) oligomers and the vascular protein fibrinogen may, when forming a complex, contribute to Alzheimer's disease.

Kivanç Birsoy is uncovering the hidden metabolic pathways that cancer cells exploit. His work could also optimize strategies for using nutrition to improve human health.

University Health and Wellness does everything from flu shots to biosafety level 3 testing.

Scientists Quarraisha Abdool Karim and Salim S. Abdool Karim, philanthropist Marlene Hess, and Nobel-prize winner Michael W. Young were also given honorary degrees.

Study provides a model for how different enzymes unfold proteins and remove tags, solving a longstanding mystery about how the two interact.

An immersive program helps undergraduates from minority-serving institutions envision futures in research

Researchers have devised a way to visualize molecules that are very rare, very small, or hard to produce naturally—including some viruses.

Newly discovered weapons of bacterial self-defense take different approaches to achieving the same goal: preventing a virus from spreading through the bacterial population.

How a modest task force grew into a campuswide commitment to greener science and smarter operations

Mutations in FANCX appear to cause a lethal form of Fanconi anemia, a finding that sheds light on unexplained pregnancy loss and offers new avenues for genetic screening.

On Wednesday, April 30, The Rockefeller University honored members of its community who reached service milestones ranging from 10 to 45 years.

Mojsov is a research associate professor whose research led to the development of drugs for obesity and diabetes.

New findings suggest neurons have much more functional dexterity than scientists previously realized.

Ines Ibañez-Tallon is revealing how an understudied region of the brain plays an outsized role in opioid and nicotine dependence. 

Open access, peer reviewed, and co-owned, the Journal of Human Immunity represents a new business model in scientific publishing.

Mojsov is recognized for her discovery of the peptide hormone GLP-1, research that led to a new class of safe and highly effective drugs for type 2 diabetes as well as the treatment of obesity.

Kivanç Birsoy and Ekaterina Vinogradova will head projects that aim to harness and bioengineer immune cells for the early detection, prevention, and treatment of disease.

Results presented at Conference on Retroviruses and Opportunistic Infections show that two broadly neutralizing antibodies can keep HIV suppressed for months.

This bold, multi-institutional collaboration will investigate how metabolism, diet, and gut microbes shape immune responses to cancer.

A surprising mix of inherited and de novo mutations in 60 genes contribute to 10 percent of CHD cases. Many of these same mutations also contribute to neurodevelopmental disorders including autism. 

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.

New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.

The author of How We Learn will be presented with Rockefeller’s prestigious science writing award on March 17.

Mei, a graduate student in Sohail Tavazoie’s lab, is being honored for work showing that a commonly inherited mutation governs breast cancer metastasis and influences survival.

Jeffrey M. Friedman’s lab has discovered a mechanism to explain how leptin resistance works.

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.

An artist-in-residence collaborates with scientists in the Kronauer lab to reveal the unseen movements of ants.

A collaboration between Rockefeller, MSK, and Weill Cornell answers a longstanding mystery about the basic biology of the hepatitis B virus, while also proposing a novel therapy.

When placed in mice, an RNA-binding protein found only in the brains of humans changed how the animals vocalized to each other.

How much does the evolution of human speech owe to one amino acid?

Male fruit flies don’t just sing to their mates; they also use sound-cancelling wing-flicks to jockey with rivals. This new understanding of how male flies compete for female partners could shed light on how the brain balances cooperation and competition.

Achieving a 41% emissions reduction, the university sets a new sustainability benchmark.

New research on nematodes reveals how glial cells maintain and monitor neuronal dendrites.

Study reveals how immune cells in the gut distinguish between food and harmful pathogens, shedding light on the origins of both food allergies and intestinal diseases.

Unpacking “finger-like” protein bundles that protrude from cells may lead to novel treatments for metastasis.  

Long classified as a subset of common liver cancer, FLC should be considered its own unique disease. Now researchers are testing a combination drug therapy that targets FLC tumors.

New research reveals how the RapA enzyme protects against R-loop cytotoxicity in E. coli.

She shares the award with three other scientists who together laid the groundwork for a new generation of drugs used to treat type 2 diabetes and obesity.

The awards are worth up to $1.5 million each over the course of up to eight years, covering both postdoctoral training and the transition to the start of an independent laboratory as a faculty member.

Every cell in the body and up to 80 percent of our genes operate under circadian control, significantly influencing our overall health. Here’s some ways to mitigate disruptions to this daily cycle.

From decoding the mysteries of memory formation to revealing cancer’s metabolic, neurologic, and genetic tricks, here are some fascinating discoveries that came out of Rockefeller in 2024.

Piscitello had been a Rockefeller-based HHMI employee since 2019. She passed away on November 22.

Daniel Kronauer’s research on an unusual ant species illuminates the biochemistry and genetics behind complex social behavior—and potentially offers clues to the evolution of our own social brains.

A newly created atlas of 21 million cells could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies.

Researchers discovered a vulnerability in viral enzymes that could lead to novel treatments for diseases as diverse as COVID and Ebola, while also minimizing side effects and reducing the odds of drug resistance.

Mounting evidence suggests that metastasis, the culprit in the vast majority of cancer deaths, is in part driven by genetic disposition. Physician-scientist Sohail Tavazoie discusses the newest research into this phenomenon, and what it may mean for breast cancer patients.

Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.

The Miller Brain Observatory, which boasts some of the most advanced imaging technology in the world, is now accepting research proposals. 

New insights could fine-tune this immunotherapy to avoid a common side effect without sacrificing efficacy.

Avi Flamholz joins Rockefeller to investigate how microbes process nutrients and how that understanding can help develop tools to better anticipate and mitigate the effects of climate change.

Freiwald is honored for his groundbreaking work revealing biological mechanisms of facial recognition.

A new cell type provides a missing piece of the neural network regulating appetite.

It acts as a sort of molecular fumigator to battle phages and plasmids.
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