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In studying the mating rituals of fruit flies, scientists may have learned something about how brains evolve

Researchers have identified how the architecture of brain circuits helps different species flexibly adapt to new mating signals across evolutionary timeframes.

West Nile infections are spiking. Here’s why the percentage of severe cases is so small

An autoimmune condition makes certain people much more susceptible to West Nile virus and many other severe viral diseases. In the future, a screening process could reveal if you’re at risk.  

Surprising reason that B cells benefit from booster shots

New research solves the mystery of how two different types B cells work in tandem to fight off re-infections, with implications for vaccine boosting strategies.

Could a bout of COVID protect you from a severe case of flu?

New findings on how past viral respiratory infections affect future, unrelated ones could lead to therapies for boosting general antiviral immunity—and potentially better pandemic preparedness.

Rockefeller launches new introductory curriculum for graduate students

The new programming, which spans the full month of September, is designed to teach essential skills and ground students in different research opportunities before lab rotations begin.

Alexander Tomasz, a trailblazer in the study of multidrug-resistant microbes, has died

His work has been crucial for the development of new antibiotics, which are urgently needed in a world where multi-resistant superbugs are a major threat to public health.

Svetlana Mojsov wins the 2024 Lasker~DeBakey Clinical Medical Research Award

Mojsov’s discovery of GLP-1 and its critical role in the regulation of insulin secretion and blood glucose led to the development of a revolutionary new class of medicines.

Rockefeller University surpasses new federal safeguards for volunteers in clinical research

The Association for the Accreditation of Human Research Protection Programs once again commended Rockefeller’s standards and practices.  

Why a promising breast cancer drug doesn’t work—and how to improve it

A treatment that appears effective in cancers such as myelofibrosis consistently fails in breast cancer clinical trials. A new study explains why.

Cancer cells may be using lipids to hide from the immune system

New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for treatment.

New findings on TB could change how we treat inflammatory disorders    

The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      

This technique for studying cell receptors could have sweeping implications for drug development

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors.

New insight into the protein mutations that cause Rett syndrome

Findings bolster the idea that the functions of this protein—MeCP2—are more centered on nucleosomes, rather than other forms of DNA.

Second genetic sensor for DNA methylation discovered

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA.

Surprising mechanism for removing dead cells identified

A tandem signaling process turns ordinary cells into an efficient cleanup crew.

Peter Chin, a computer support specialist and authority on Apple technology, has died

A Rockefeller employee since 2001, Chin will be missed by many in the community who came to rely on his deep technical expertise and graceful approach to problem solving.

Knocking out one key gene leads to autistic traits

Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.

Many people with severe brain injuries are far more cognitively aware than they seem

Rockefeller University Hospital developed a model clinical infrastructure for the study, as well as helped conduct it.

How Rockefeller University Hospital became a leading facility for neuroscience research

An ambitious study inspired a transformational renovation.

Link discovered between sensory neurons and breast cancer metastasis

Researchers found a “neuro-cancer axis”  that may promote the spread of breast cancer. They also found that an FDA-approved anti-nausea medication may prevent it.

New supportive community for first-year graduate students underway

Students in the BIOGROW program participate in professional development and community building events in collaboration with the university's Office of Diversity, Equity, and Inclusion.

Postdoctoral Association Summer Seminar Series underway

Every summer, Rockefeller postdocs and students take to the stage to share their latest research.

Gabriel Victora named HHMI Investigator

Victora, who studies how antibodies are generated in response to infection and immunization, is among 26 scientists nationwide to receive this designation.

Rockefeller celebrates inaugural DEI awards

Four community members—Sadye Paez, Elizabeth Campbell, Yuriria Vázquez, and Chad Morton—were recognized for their advocacy work both within the university and in the wider scientific community.

New genetic tool could identify drug targets for diseases associated with metabolic dysfunction

A novel platform for identifying metabolic gene functions has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism.

Asexual reproduction usually leads to a lack of genetic diversity. Not for these ants.

Parthenogenic species must compensate for their limited gene pool or risk extinction.

Campus-wide celebration marks President Emeritus Torsten N. Wiesel’s 100th Birthday

President Lifton hosted a community celebration of Wiesel, a Nobel laureate as well as former university president.

Researchers capture never-before-seen view of gene transcription

New tech reveals findings that address long-standing theories about how bacteria begin the process of making RNA from DNA.

Elizabeth Campbell launches Laboratory of Molecular Pathogenesis

The infectious disease specialist will continue her groundbreaking work on the transcriptomes of the pathogens behind tuberculosis and Covid.

Leslie B. Vosshall honored with the Dickson Prize in Medicine

Vosshall is recognized for her pioneering studies of the mosquito Aedes aegypti, which transmits pathogens causing human diseases including dengue, Zika, chikungunya, and yellow fever.

Light-weight microscope captures large-scale brain activity of mice on the move

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments.

Surprising origins for a rare cancer

An unexpected discovery may pave the way to better treatments for a broad range of cancers.

What we need to worry about with avian flu—and what we don’t 

Since first detected in birds in 2021, avian flu has killed millions of poultry and infected animals once thought to be immune. What early warning signs could point to an increasing risk for humans?

Winrich Freiwald wins the 2024 Kavli Prize for Neuroscience

The researcher is being honored for his discovery of a specialized system in the brain’s neocortex that is responsible for recognizing faces.

38 students receive Ph.D.s at Rockefeller’s 66th convocation

Nobel laureate Frances H. Arnold, STEM advocate Freeman A. Hrabowski, III, and climatologist Michael E. Mann also received honorary degrees.

Key mechanism for maintaining proper telomere length identified 

New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1.

Heilbrunn Nurse Scholar Award Celebrates 10 Years

The program supports research on nursing within the context of clinical and translational science.

AI could accelerate drug discovery. But only if we can trust it.

The advent of AlphaFold3 could be an unprecedented boon for drug development. Computational biologist Jiankun Lyu discusses the pros and cons of the tech, and his work analyzing the algorithm.

How memories crystallize over time

“Practice makes perfect” is no mere cliché. It's neuroscience.

Researchers may have found an Achilles heel for hepatitis B

New understanding of how the virus replicates could lead to new therapeutic targets for HBV.

Cori Bargmann receives Gruber Neuroscience Prize

Bargmann is recognized for her role in linking genetics with behavior.

Paul Bieniasz elected to the National Academy of Sciences

Bieniasz is being honored for his work on the life cycle of retroviruses and their interactions with host proteins. With his election, nearly half of Rockefeller faculty are NAS members.

Rockefeller joins city partnership to reduce carbon footprint

As part of the Plant-Powered Carbon Challenge, the university will offer more plant-based dining options on campus.

Newly discovered brain pathway sheds light on addiction

The findings in mice may explain how addictive drugs hijack natural reward processing systems, creating the urge to use while throwing natural urges to eat and drink off-kilter.

Svetlana Mojsov named one of TIME100 Most Influential People of 2024

The annual list honors artists, innovators, leaders, and pioneers in a variety of fields.

Rockefeller holds annual Employee Anniversary Celebration

The university celebrated staff and faculty who retired or reached notable work anniversaries in 2023.

Why some people with rheumatoid arthritis have pain without inflammation

Researchers have identified a suite of genes explaining the disconnect between diagnosis and symptom.

New technique sheds light on memory and learning

The findings may also have implications for learning and memory disorders, including Fragile X syndrome.

How one scientist's fascination with RNA changed medicine forever

Thomas Tuschl has devoted his career to making discoveries that bridge the gap between bench and business—and have resulted in entirely new classes of drugs.

Stem cell model offers first glimpse of early human development

The new platform’s ethically grounded approach promises to reveal much about how human embryos form during the earliest stages of pregnancy.

Theoretical physicist Carlo Rovelli receives 2024 Lewis Thomas Prize

The author of There Are Places in the World Where Rules Are Less Important Than Kindness was presented with Rockefeller’s prestigious science writing award on April 9.

The SNF Institute for Global Infectious Disease Research announces new advisory board

SNFiRU, which aims to better understand the agents that cause infectious disease and to lower barriers to treatment and prevention globally, launched numerous initiatives in its inaugural year.

New Mtb study offers a novel paradigm for understanding bacterial transcription

A novel sequencing technique reveals a genetic trick TB may be using to evade the immune system and resist antibiotics.

A pioneering way to target the culprit behind a deadly liver cancer

Researchers have translated a cutting-edge tactic for treating genetic disorders into a fresh approach for potentially stymying cancer.  

Vitamin A may play a central role in stem cell biology and wound repair

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.

New study on mating behaviors offers clues into the evolution of attraction

In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.

Universal tool for tracking cell-to-cell interactions

uLIPSTIC, an updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.

Innovative microscopy tech answers fundamental questions

A powerful tool captures data from an unprecedented 1 million neurons simultaneously, painting a much fuller picture of brain dynamics.

Rogue enzymes cause numerous diseases. A new method could help design drugs to treat them.

A novel platform allows researchers to directly target enzymes implicated in infectious diseases, several genetic disorders, and some cancers for the first time.
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