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The decision to eat may come down to these three neurons

Manipulating a newly identified neural circuit can curb appetite—or spur massive overeating.

New discovery offers hope for vastly improved myasthenia gravis treatment

A new, enzyme-based drug dramatically outperforms existing treatments in mouse models, paving the way for future clinical trials and the potential to treat myasthenia gravis and similar diseases.

In studying the mating rituals of fruit flies, scientists may have learned something about how brains evolve

Researchers have identified how the architecture of brain circuits helps different species flexibly adapt to new mating signals across evolutionary timeframes.

West Nile infections are spiking. Here’s why the percentage of severe cases is so small

An autoimmune condition makes certain people much more susceptible to West Nile virus and many other severe viral diseases. In the future, a screening process could reveal if you’re at risk.  

Surprising reason that B cells benefit from booster shots

New research solves the mystery of how two different types B cells work in tandem to fight off re-infections, with implications for vaccine boosting strategies.

Could a bout of COVID protect you from a severe case of flu?

New findings on how past viral respiratory infections affect future, unrelated ones could lead to therapies for boosting general antiviral immunity—and potentially better pandemic preparedness.

Rockefeller launches new introductory curriculum for graduate students

The new programming, which spans the full month of September, is designed to teach essential skills and ground students in different research opportunities before lab rotations begin.

Alexander Tomasz, a trailblazer in the study of multidrug-resistant microbes, has died

His work has been crucial for the development of new antibiotics, which are urgently needed in a world where multi-resistant superbugs are a major threat to public health.

Svetlana Mojsov wins the 2024 Lasker~DeBakey Clinical Medical Research Award

Mojsov’s discovery of GLP-1 and its critical role in the regulation of insulin secretion and blood glucose led to the development of a revolutionary new class of medicines.

Rockefeller University surpasses new federal safeguards for volunteers in clinical research

The Association for the Accreditation of Human Research Protection Programs once again commended Rockefeller’s standards and practices.  

Why a promising breast cancer drug doesn’t work—and how to improve it

A treatment that appears effective in cancers such as myelofibrosis consistently fails in breast cancer clinical trials. A new study explains why.

Cancer cells may be using lipids to hide from the immune system

New study demonstrates that one type of lipid is so critical for immune evasion that certain cancers cannot proliferate without them. Modulating intake of dietary lipids could open up an avenue for treatment.

New findings on TB could change how we treat inflammatory disorders    

The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      

This technique for studying cell receptors could have sweeping implications for drug development

Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors.

New insight into the protein mutations that cause Rett syndrome

Findings bolster the idea that the functions of this protein—MeCP2—are more centered on nucleosomes, rather than other forms of DNA.

Second genetic sensor for DNA methylation discovered

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA.

Surprising mechanism for removing dead cells identified

A tandem signaling process turns ordinary cells into an efficient cleanup crew.

Peter Chin, a computer support specialist and authority on Apple technology, has died

A Rockefeller employee since 2001, Chin will be missed by many in the community who came to rely on his deep technical expertise and graceful approach to problem solving.

Knocking out one key gene leads to autistic traits

Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.

Many people with severe brain injuries are far more cognitively aware than they seem

Rockefeller University Hospital developed a model clinical infrastructure for the study, as well as helped conduct it.

How Rockefeller University Hospital became a leading facility for neuroscience research

An ambitious study inspired a transformational renovation.

Link discovered between sensory neurons and breast cancer metastasis

Researchers found a “neuro-cancer axis”  that may promote the spread of breast cancer. They also found that an FDA-approved anti-nausea medication may prevent it.

New supportive community for first-year graduate students underway

Students in the BIOGROW program participate in professional development and community building events in collaboration with the university's Office of Diversity, Equity, and Inclusion.

Postdoctoral Association Summer Seminar Series underway

Every summer, Rockefeller postdocs and students take to the stage to share their latest research.

Gabriel Victora named HHMI Investigator

Victora, who studies how antibodies are generated in response to infection and immunization, is among 26 scientists nationwide to receive this designation.

Rockefeller celebrates inaugural DEI awards

Four community members—Sadye Paez, Elizabeth Campbell, Yuriria Vázquez, and Chad Morton—were recognized for their advocacy work both within the university and in the wider scientific community.

New genetic tool could identify drug targets for diseases associated with metabolic dysfunction

A novel platform for identifying metabolic gene functions has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism.

Asexual reproduction usually leads to a lack of genetic diversity. Not for these ants.

Parthenogenic species must compensate for their limited gene pool or risk extinction.

Campus-wide celebration marks President Emeritus Torsten N. Wiesel’s 100th Birthday

President Lifton hosted a community celebration of Wiesel, a Nobel laureate as well as former university president.
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