Over 130 scientists in 18 labs are conducting research to advance the development of new, urgently needed approaches for the prevention and treatment of COVID-19.
Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.
Allis, whose pioneering research established that enzymes that modify histone proteins, which package DNA in the nucleus, regulate gene expression, has been elected to the National Academy of Medicine.
Scientists have found that many receptors with high potential for drug discovery take a different configuration inside the body than in the test tube. The findings could explain why some promising drugs fail in clinical trials, and potentially open doors to new drug-development approaches.
Ruta, who investigates how the brain is modified by experience, has received a MacArthur Fellowship, an award intended to encourage people of outstanding talent to pursue their own creative, intellectual, and professional inclinations.
Cell division is critical to creating and sustaining life. It’s also incredibly difficult to study. Now, advanced technology is enabling researchers to take their understanding of this process to the next level.
For the brain to function smoothly, its cells must carefully regulate which proteins are produced and when. By studying gene regulation, researchers are now shedding light on complex brain conditions like autism and stroke.
Drugs known as potentiators alleviate some symptoms of cystic fibrosis. Researchers recently figured out how these compounds work—a finding that may lead to better drugs that patients can more easily afford.
Animals learn the hard way which sights, sounds, and smells are relevant to survival. New research in flies shows that the timing of these cues plays an important role in how mental associations arise, and elucidates brain pathways involved in this process.
