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Displaying 132 of 2899 articles.

New animal models for hepatitis C could pave the way for a vaccine

In the rats that roam New York City’s streets and tunnels, scientists have found a virus that resembles hepatitis C. They have used it to create the first animal model of the human disease, a breakthrough that potentially could yield a much-needed vaccine.

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In brief: A glimpse into the origins of antibiotic resistance

Scientists have identified several genetic mechanisms by which antibiotic resistance may have arisen in a bacterium that causes deadly infections.

A hidden movement in the molecule that makes RNA

Researchers have uncovered new details about the molecular machine that separates DNA strands before copying a gene's sequence into RNA.

In brief: Mapping the errors that disrupt heartbeat

By determining the structure of a protein linked to a deadly form of arrhythmia, scientists have gained new insights about the condition.

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In brief: A closer look at why some drugs cause arrhythmia

Scientists have identified the features that render a potassium channel in the heart vulnerable to interference by a range of drugs.

C. David Allis wins 2017 March of Dimes Prize in Developmental Biology

Allis has received the March of Dimes Prize in Developmental Biology. The award, given to investigators whose research offers hope for the prevention and treatment of birth defects and other infant diseases, honors Allis for his groundbreaking work on gene regulation.

Discovery of a Zika antibody offers hope for a vaccine

Searching for a way to thwart Zika, scientists have discovered an antibody with a potent ability to neutralize the virus.

Shooting the messenger: how one protein allows germ cells to develop

Researchers have identified a molecule that guides the formation of eggs and sperm by preventing a host of factors related to cell death and inflammation from killing the precursors to these cells. Their findings reveal new knowledge about how a mutation in this molecule leads to male sterility.

New study resolves the structure of the human protein that causes cystic fibrosis

In order to better understand how genetic mutations give rise to cystic fibrosis, researchers need to map the protein responsible for the disorder. The new structure has led to new insights on how this molecular channel functions.

A new way to reset gene expression in cancer cells shows promise for leukemia treatment

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by d...