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Displaying 124 of 2841 articles.

Shape-shifting protein protects bacteria from invaders

Researchers have discovered how bacteria manage to destroy enemy DNA, while keeping their own genetic material safe.

First mapping of cells in the early human placenta to advance research on problem pregnancies

Scientists have made the first comprehensive inventory of cells present in the human placenta of the first trimester, a stage when many pregnancy complications are thought to arise. The findings could fuel new research on conditions such as preeclampsia and pre-term birth.

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Enzyme structure helps to explain how protein factories are constructed

Researchers characterized the structure of Mdn1, an enzyme key to making ribosomes.

Sohail Tavazoie promoted to professor

Sohail Tavazoie, a physician-scientist who studies the genes that regulate a tumor’s ability to metastasize, has been promoted to professor.

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Structural studies help explain how cancer cells resist chemotherapy

New research sheds light on how some cancer cells use molecular pumps to expel chemotherapy drugs before they have a chance to work.

Scientists map the portal to the cell’s nucleus

The gateway to cellular headquarters has 552 components. A new map that shows how all these pieces fit together could help scientists study numerous diseases.

Scientists caution that a rare childhood liver cancer can spread to the brain

A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.

Molecular doorstop could be key to new tuberculosis drugs

In discovering how an antibiotic kills the bacteria that cause tuberculosis, scientists open the door to new treatments for the disease—and possibly others, as well.

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Building the machinery that makes proteins

Scientists have used cryo-electron microscopy to capture the very first snapshots of the large ribosomal subunit—part of the ribosome responsible for forging bonds between amino acids, the building blocks of proteins—coming together.

Molecule discovered in dirt could help against multi-resistant bacteria

In mining soil for natural drugs, scientists have discovered a brand-new antibiotic potent against many bacteria. They hope it could be used to treat infections that cannot be stopped with existing drugs.