User Fees

The PRC has designed a modular pricing model where cost of an analysis is based on what needs to be done. Pricing is based on use of resources. All components charged and used for an analysis are shown on our invoices and the cost of all components are available for Fiscal Year 2021 (July 1 2020 through June 30 2021) . Internal Rockefeller users can access sample information, progress as well as final invoices at:  https://plims.rockefeller.edu/status/ . Prices for walk-up instrumentation is show here.

We understand that it can be difficult to understand and decide which tools/components are needed for an analysis and we have therefore shown the components and costs of 6 typical requests below.

• • • Simple SDS-PAGE gel band analysis ($ internal / $ external).

      1  Digestion..................$   75 / $  127
      1  LC-MS/MS hour..............$   77 / $  133
      Total.........................$  152 / $  260
      
      

    • Co-ip/Affinity type analysis with two conditions and 3 biological replicates ($ internal / $ external).

      6  Reduction & Alkylation.....$  150 / $  282
      6  Digestion..................$  450 / $  762
      6  Clean-up...................$  150 / $  282
      12 LC-MS/MS hour..............$  924 / $1,596
      Total.........................$1,674 / $2.922
      
      

    • Phosphopeptide enrichment and analysis ($ internal / $ external).

      1  Reduction & Alkylation.....$   25 / $   47
      1  Digestion (large)..........$  103 / $  164
      1  Clean-up (large)...........$   40 / $   60
      1  Phosphopeptide Enrichment..$  110 / $  175
      3  LC-MS/MS hour..............$  231 / $  399
      Total.........................$  509 / $  845
      
      

    • TMT-based protein quantitation of 16 samples ($ internal /$ external).

      16 Reduction & Alkylation.....$  400 / $  752
      16 Digestion (large)..........$1,200 / $2,032
      16 TMT labeling w/label check.$2,240 / $3,552
      1  Mg-amount cleanup..........$   40 / $   60
      1  Micro-fractionation........$  300 / $  451
      20 LC-MS/MS hour..............$1,540 / $2,660
      Total.........................$5,720 / $9,507
      
      

    • Profiling of polar metabolites in 36 samples ($ internal / $ external).

      36 Polar Metabolite Profiling.$  468 / $  n/a
      19h Data analysis.............$  513 / $  n/a
      Total.........................$  981 / $  n/a
      
      

    • Synthesis of 15-mer peptide at 25 micromol scale with purification ($ internal / $ external).

      15 Amino acid (25µmol)........$  225 / $  330
      1  Purification...............$  197 / $  331
      Total.........................$  422 / $  661