User Fees

The PRC has designed a modular pricing model where cost of an analysis is based on what needs to be done. Pricing is based on use of resources. All components charged and used for an analysis are shown on our invoices and the cost of all components are available for Fiscal Year 2027 (July 1 2026 through June 30 2027) . Internal Rockefeller users can access sample information, progress as well as invoices at:  https://plims.rockefeller.edu/status/ . Prices for walk-up instrumentation is shown here.

We understand that it can be difficult to understand and decide which tools/components are needed for an analysis. Below are show examples of requests with typical components added.

      • Simple SDS-PAGE gel band analysis (Internal / External / For-Profit). 
        1  Digestion......................$    92 / $   152 / $   337
1  LC-MS/MS hour..................$    94 / $   160 / $   344
Total.............................$   186 / $   312 / $   681
      • Co-Ip/Affinity type analysis with two conditions and 3 biological replicates (Internal / External / For-Profit). 
        6  Reduction & Alkylation.........$   186 / $   354 / $   684
6  Digestion......................$   552 / $   912 / $  2022
6  Clean-up.......................$   180 / $   342 / $   660
9  LC-MS/MS hour..................$   846 / $  1440 / $  3096
Total.............................$  1764 / $  3048 / $  6462
      • Phospho peptide enrichment and analysis – one sample (Internal / External / For-Profit). 
        1  Reduction & Alkylation.........$    31 / $    59 / $   114
1  Digestion......................$    92 / $   152 / $   337
1  Sep-Pak cleanup................$    30 / $    45 / $   110
1  Enrichment (TiO2)..............$   133 / $   212 / $   487
1  Enrichment (iMAC)..............$   133 / $   212 / $   487
5  LC-MS/MS hour..................$   470 / $   800 / $  1720
Total.............................$   889 / $  1480 / $  3255
      • TMT-based protein lysate quantitation of 18 samples (Internal / External / For-Profit). 
        18 Reduction & Alkylation.........$   558 / $  1062 / $  2052
18 Digestion......................$  1656 / $  2736 / $  6066 
18 TMT labeling w/label check.....$  2952 / $  4788 / $ 10818
1  Micro cleanup..................$    30 / $    45 / $   110
1  Sep-Pak cleanup................$    30 / $    45 / $   110
1  SCX/high-pH-fractionation......$   563 / $   846 / $  2062
32 LC-MS/MS hour..................$  3008 / $  5120 / $ 11008
Total.............................$  8797 / $ 14654 / $ 32226
      • MS1 based targeted profiling  of 200+ polar metabolites: 36 sample, with heavy standards and some simple sample preparation (Internal / External / For-Profit). 
        36 Heavy Standard.................$   252 / $   360 / $   936
36 Simple Preparation.............$   180 / $   280 / $   648
17 LC-MS hour.....................$   850 / $  2040 / $  3111
1  Data Analysis targeted 20+.....$  2000 / $  3000 / $  7325
Total.............................$  3282 / $  5688 / $ 12020
      • MS2 based untargeted analysis of polar metabolites: 36 sample, with heavy standards and some simple sample preparation (Internal / External / For-Profit). 
        36 Heavy Standard.................$   252 / $   360 / $   936 
36 Simple Preparation.............$   180 / $   280 / $   648
32 LC-MS/MS hour..................$  1600 / $  3840 / $  5856
1  Database query.................$    50 / $   100 / $   183
1  DDA data analysis..............$  1000 / $  2000 / $  3662
Total.............................$  3082 / $  6588 / $ 11285
      • MS2 based untargeted analysis of lipids: 36 sample, with heavy standards and some simple sample preparation (Internal / External / For-Profit). 
        36 Heavy Standard.................$   252 / $   360 / $   936 
36 Simple Preparation.............$   180 / $   280 / $   648
41 LC-MS/MS hour..................$  2050 / $  4920 / $  7503
1  Database query.................$    50 / $   100 / $   183
1  DDA data analysis..............$  1000 / $  2000 / $  3662
Total.............................$  3532 / $  7668 / $ 12932
      • MS1 based targeted profiling of 200+. Primary data shared w/o preparation, heavy standards or data analysis: 10 samples (Internal / External / For-Profit). 
        5  LC-MS hour.....................$   250 / $   600 / $   915
Total.............................$   250 / $   600 / $   915