News & Announcements
March 18, 2020. The PRC is shutdown in response to COVID-19. PRC team members are available by email or similar!
February 21, 2020. First TMT 16-plex experiment completed.
December 17, 2019. Alexandra Pagano joins the PRC. Alexandra have previously worked at Pfizer and brings MRM experience.
September 3, 2019. Bety Rostandy from UNC starts at the PRC.
March 13, 2019. Ian Maze’s paper: Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 is published in Nature.
February 28, 2019. Q-Exactive HF enters production.
January 28, 2019. Dr. Hanan Alwaseem, chemist from Rochester University, begins at the PRC.
December 21, 2018. Joseph Fernandez, RU analytical biochemist retires after 31 year career at the PRC. Joe collaborated with no fewer than five Rockefeller Nobel Prize winning scientists along with many others while enjoying his love of scientific endeavor in the city he is proud to be born and raised in. His efforts resulted in 35 publications in top tier journals for the PRC.
June 25, 2018. Dr. Soren Heissel, proteomic mass spectrometrist from University of Southern Denmark, begins at the PRC.
May 26, 2016. First ‘real’ sample analyzed on the Sohn Conference Foundation funded mass spectrometer (Fusion Lumos mass spectrometer).
May 19, 2016. The installation of the Fusion Lumos mass spectrometer generously funded by the Sohn Conference Foundation is completed. The mass spectrometer (aka: ‘The Sohn Spectrometer’) is expected to be fully implemented August 2016.
April 1, 2016. A ‘Proteome Discoverer’ data interpretation reference guide has been generated and is available for download here.
January 8, 2016. The Rita and Frits Markus Library at Rockefeller University and the Memorial Sloan Kettering Library are collaborating to collect information in regards to the scholarly communication and data management practices in labs at both campuses.
To help us understand the potential services we can develop to support our researchers, we are currently conducting a survey of our respective research communities. The survey takes approximately ten minutes and can be completed by someone familiar with the lab’s publication and data management practices.
August, 2015. The Sohn Conference Foundation has approved a Grant of $800,000 providing for a new state-of-the-art mass spectrometer for the Proteomics Resource Center.
July 1, 2015. Ian Maze’s paper: Critical Role of Histone Turnover in Neuronal Transcription and Plasticity is accepted. The report investigates the dynamic of Histone 3.x using a wide range of technologies and is indeed a ‘heavy-on-data‘ publication.
June 11, 2015. The Q-Exactive mass spectrometer generously funded by the Leona M. and Harry B. Helmsley Charitable Trust has been upgraded to a Q-Exactive Plus.
February 28, 2014. Brian Dill, Ph.D. (http://www.ncbi.nlm.nih.gov/pubmed/?term=Dill+BD) started as a scientist in the Center. Brian contributes with a strong background in biology and several years of experience in global proteomics.
June 7, 2013. The Proteomics Resource Center of the Rockefeller University has an immediate opening for a Research Support Specialist in the area of mass spectrometry/proteomics (position # IRC13775). The successful candidate will support highly recognized research programs at Rockefeller University located in the New York City. The complete description can be found at: http://www.rockefeller.edu/hr/jobs.php. Update on February 28, 2014: The position has been filled.
May 17, 2013. A new ‘CUSTOM PEPTIDE & PEPTIDE LIBRARY SUBMISSION FORM‘ is now available. The new form is designed with ease-of-use in mind using drop-down menus and check boxes.
May 12, 2013. After years of experience in supplying peptides to the Rockefeller University community we know that some peptides are needed again and again. We therefore keep a group of stock peptides, often used for Affinity Purification, Immunological Studies, CEF Control, yeast and histone biology. These stock peptides can be supplied same day or next day depending on your location. Amount can be as required by the investigator, but commonly 25-50 milligrams of elution peptides are required, 10 milligrams of peptide for immunological study and multiples of 100 milligrams for alpha factor. Should you find peptides that you often use to be missing from these lists please contact us so that we may add them for you. List of ‘Stock Peptides’ available here.
October 3, 2012. The PerSeptive Biosystems MALDI ToF DE-STR mass spectrometer (designed more than two decades ago) has been equipped with an updated computer and operating
system. This modernized computer will hopefully prolong the useful life of this important and easy to use “walk-up” user instrument.
July 1, 2012. A new price scheme has been introduced (https://www.rockefeller.edu/proteomics/services-and-fees/). Because MS based proteomics is often used as discovery/hypothesis-free strategy samples matrixes varies considerably. It is overly presumptuous to treat all samples alike and the Proteomics Resource Center at The Rockefeller University therefore conducts experiments using a ‘tool box’ where each tool is priced accordingly. This allows a precise tailoring of a proteomics experiment to an individual sample, and at the same time provides for fair and transparent pricing of experiments.
April 10, 2012. Q-Exactive mass spectrometer has now been incorporated into workflows at the Proteomics Resource Center. The first larger data analysis has been completed and in a GeLCMS approach (12 gel slices of a human cell lysate) 4,500 proteins were matched at a False Discovery Rate (FDR) of 1%.
February 9, 2012. A new mass spectrometer (Q-Exactive) coupled with HPLC has been installed at the Center. The new setup is expected to be available for analysis mid-March. The new mass spectrometer is graciously funded by the Leona M. and Harry B. Helmsley Charitable Trust.
January 6, 2012. In an effort to simplify the usage computation for the walk-up user instrumentation, we will require you to log in to the Voyager MALDI and/or the Typhoon Scanner with your RU email log-in name. The password will be sent to your email address this month. The first time you use the Voyager MALDI and the Typhoon Scanner after having received your individual password we encourage you to change the password to one of your choice. New users and anyone who does not receive a password should see Susan R. Powell in RRB 157 or contact her at x8446 or email: firstname.lastname@example.org.
The ‘old’ way of logging used time (and user) in the time sheet hard copy will be in place until February 1, 2011. Hereafter, the use of username and password will be mandatory when accessing the instrument(s).
December 2, 2011. The Proteomics Resource Center has placed an order for an additional HPLC equipped state-of-the-art mass spectrometer. The new mass spectrometer Q-Exactive (launched by ThermoScientific at ASMS Annual Conference in June this year) will be coupled to a Dionex nano-flow HPLC system. The Q-Exactive is a hybrid mass spectrometer composed of a quadrupole and an orbitrap and will be able to deliver not only high resolution and sub-ppm mass accuracy data for peptides, but it will also enable mass measurement of fragmented peptides with high-resolution and accurate-mass (HR/AM). All ions will be detected in the orbitrap. The new system is planned to be used mainly for PTM analysis and global proteomics. Expected delivery: Early 2012.
September 1, 2011. Dr. Henrik Molina was appointed Director of the Proteomics Resource Center and Research Assistant Professor on September 1, 2011. Dr. Molina received his Ph.D. from the University of Southern Denmark, while working in the Laboratory of Dr. Akhilesh Pandey at the Johns Hopkins University. He completed a postdoctoral position with Pandey’s Laboratory before assuming direction of the Proteomic Core at the Center for Genome Regulation (CRG), Barcelona, a position he held until immediately before starting at Rockefeller. Henrik Molina’s experience also counts 5 years in a proteomics based biotech company co-founded by Matthias Mann.
Henrik Molina can be contacted at ext. 7525 or by email at hmolina [a] rockefeller dot edu.