Thirty years ago, an insight from a rare brain disease took Robert Darnell's career in an unexpected direction. He’s still surprised by what he’s learning.
In a new study, scientists uncover thousands of previously hidden genes and reveal ancient chromosome structures, with sweeping implications for the study of neuroscience and evolution.
Gabriel D. Victora's team has turned germinal centers into a living laboratory for one of biology's oldest questions: how much of evolution is shaped by chance?
A new study reveals how germinal centers produce powerful antibodies through noisy rounds of mutation and selection, offering new insight into vaccine design—and larger themes in evolution.
Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight that could inform research into cancer and other diseases.
A new study shows that preexisting autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to this one kind of Chikungunya vaccine, which is no longer available in the U.S.
Replicative aging of human cells, the result of telomere shortening, is slower at physiological oxygen than at atmospheric oxygen, a difference now shown to be due to low oxygen impairing the ATM kinase response to withered telomeres.
Researchers have learned that the antioxidant glutathione, when operating inside mitochondria, is a key factor enabling tumors to spread from the breast to the lung.
