An autoimmune condition makes certain people much more susceptible to West Nile virus and many other severe viral diseases. In the future, a screening process could reveal if you’re at risk.
The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.
New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1.
The end replication problem dictates that telomeres shrink unless telomerase intervenes. But the problem is actually twice as complicated, with telomerase providing only part of the solution.
The absence of a single immune cell receptor has been linked to both fewer defenses against mycobacterial infections, such as TB, and damaging buildup of sticky residue in the lungs.
Birsoy is honored for groundbreaking research uncovering metabolic weaknesses of diseased cells, such as cancer, while shedding light on debilitating mitochondrial diseases and rare genetic disorders.
With 40% of encephalitis cases now explained by an autoimmune deficiency, West Nile virus "is by far the best understood human infectious disease in the world. It’s stunning.”
A trio of faulty genes fail to put the brakes on the immune system’s all-out assault on SARS-CoV-2, leading to the inflammatory overload characteristic of MIS-C.
A new study suggests that stem cells are able to integrate cues from their surroundings and coordinate their behavior across tissue through networks of vasculature in their close vicinity.
A mutated gene may explain why some Staphylococcus aureus infections turn lethal, a finding with significant implications for people living with 5p- syndrome.
Birsoy's groundbreaking research has highlighted key nutrients that cancer cells need to survive, while shedding light on debilitating mitochondrial diseases and rare genetic disorders.
The findings, which may have implications for a wide range of human diseases, suggest that nuclear pore complexes vary in structure and function even within a single nucleus.
Scientists have identified hundreds of llama-derived antibodies that potentially could be developed into a COVID treatment. They hope such a drug would be potent against different variants of the coronavirus, including Omicron.
Epidermal stem cells that hail from the hair follicle retain memories of their journey to the skin's surface. Those memories are a boon for wound repair, but may also contribute to chronic diseases and cancer.
If COVID-19 lockdowns scrambled your sleep schedule and stretched your waistline, you're not alone. Fruit flies quarantined in test tubes sleep too little and eat too much after only one week of social isolation.
New research casts doubt on a genetic test used to screen would-be embryos for IVF implantation. The findings suggests that these embryos can develop into healthy babies regardless of whether or not they’ve been flagged as defective by the test.
