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Displaying 204 of 2824 articles.

The gene hunt to explain why some young, healthy people die from COVID-19

People under 50 without preexisting conditions typically develop mild symptoms of coronavirus infection—but there are exceptions. Researchers are working to identify rare genetic variations that may explain why some in this group have succumbed to the disease.

Rockefeller scientists launch a broad range of studies into novel coronavirus

Over 130 scientists in 18 labs are conducting research to advance the development of new, urgently needed approaches for the prevention and treatment of COVID-19.

Patient with unusually severe infection leads scientists to a rare type of immune deficiency

A rare genetic change may explain why some people die from cytomegalovirus, a stealth pathogen that is often asymptomatic.

New clues about why a universal flu vaccine is so elusive

To scientists' surprise, the immune system develops its response to each virus variant mostly from scratch, instead of building on what it has already learned.

Researchers discover a new mechanism in childhood kidney cancer

A problem in reader proteins that identify which gene is up for expression may cause normal cells to turn malignant during development.

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Study sheds new light on how epigenetic events might spur disease

Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.

Study pinpoints rare genetic change that may boost risk of HPV-related illness

The human papilloma virus is usually kept in check by the immune system, but scientists identified a genetic variant that makes some infected children prone to developing warts in the throat.

C. David Allis elected to the National Academy of Medicine

Allis, whose pioneering research established that enzymes that modify histone proteins, which package DNA in the nucleus, regulate gene expression, has been elected to the National Academy of Medicine.

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Study gives clues to the origin of Huntington’s disease, and a new way to find drugs

Using a new technique to study brain development, scientists were able to trace the causes of Huntington's back to early developmental stages when the brain has only just begun to form.

Jeffrey M. Friedman to receive 2020 Breakthrough Prize in Life Sciences

Friedman's discovery of the hormone leptin has transformed our understanding of obesity.