Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.

A collaboration between Rockefeller, MSK, and Weill Cornell answers a longstanding mystery about the basic biology of the hepatitis B virus, while also proposing a novel therapy.

When placed in mice, an RNA-binding protein found only in the brains of humans changed how the animals vocalized to each other.

How much does the evolution of human speech owe to one amino acid?

New research on nematodes reveals how glial cells maintain and monitor neuronal dendrites.

A newly created atlas of 21 million cells could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies.

New insights could fine-tune this immunotherapy to avoid a common side effect without sacrificing efficacy.

An autoimmune condition makes certain people much more susceptible to West Nile virus and many other severe viral diseases. In the future, a screening process could reveal if you’re at risk.  

The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      

New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1.