News & HighlightsNews
A scientist’s 30-year quest reveals why a fat-sensing hormone can lose its effectiveness, leading to obesity
Jeffrey M. Friedman’s lab has discovered a mechanism to explain how leptin resistance works.
Researchers discover a cause of leptin resistance—and how to reverse it
Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss.
How solving a hepatitis B paradox opened the door to new therapies
A collaboration between Rockefeller, MSK, and Weill Cornell answers a longstanding mystery about the basic biology of the hepatitis B virus, while also proposing a novel therapy.
Researchers identify a gene potentially linked to the evolution of spoken language
When placed in mice, an RNA-binding protein found only in the brains of humans changed how the animals vocalized to each other.
A single protein may have helped shape the emergence of spoken language
How much does the evolution of human speech owe to one amino acid?
Researchers uncover key insights into how the body protects against neuron damage
New research on nematodes reveals how glial cells maintain and monitor neuronal dendrites.
Study reveals how unexpected shifts in cell populations are revising our understanding of the aging process
A newly created atlas of 21 million cells could upend long-held assumptions about how we age and provide fresh directions for anti-aging therapies.
Study explains why checkpoint inhibitors so adept at fighting cancer may also leave patients vulnerable to infections
New insights could fine-tune this immunotherapy to avoid a common side effect without sacrificing efficacy.
West Nile infections are spiking. Here’s why the percentage of severe cases is so small
An autoimmune condition makes certain people much more susceptible to West Nile virus and many other severe viral diseases. In the future, a screening process could reveal if you’re at risk.  
New findings on TB could change how we treat inflammatory disorders    
The study explains why treatments for many autoimmune and inflammatory diseases raise the risk of contracting TB—and also upends long-held assumptions about what kicks off an immune response.      
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