DEET, a chemical in bug sprays, affects the behavior of highly diverse organisms—but how it works remains unclear. New research in C. elegans shows that the compound exploits unique receptors and neurons to interfere with the animals’ response to odors.
Using gene editing technology, researchers have developed a new way to study B cell activation in mice. This technique makes research more efficient, and has the potential to improve our understanding of immune responses in humans.
Risca explores the three-dimensional structures that organize and support DNA, and the biochemical rules that govern the organization of the genome. She will join Rockefeller as an assistant professor on January 2, 2019.
Researchers describe, for the first time, the structure of a smell-receptor protein common among insects. Its inner architecture illuminates how insects evolved to detect an amazing diversity of odors.
Scientists describe a group of proteins that protect cells from a subtype of human papilloma virus. They also outline genetic mutations that make this virus unusually harmful in people with epidermodysplasia verruciformis, a rare skin condition.
Researchers find that a deficiency of acetyl-L-carnitine is associated with a particular subtype of depression. Individuals with very low levels of this molecule often have highly severe symptoms and don’t respond to traditional antidepressants.
A new study in ants identifies a peptide that plays an important role in regulating reproduction. This research illuminates a potential trajectory for the evolution of distinct social castes—workers and queens.
Earlier this month, developmental biologist Amy Shyer joined the Rockefeller community as an assistant professor. Shyer combines mechanical and molecular perspectives to better understand how patterns form and how tissues develop.
Sean Brady, Winrich Freiwald, and Luciano Marraffini have been promoted to professor. Respectively, these scientists have characterized previously unknown small molecules, provided insight into how the brain processes faces, and revolutionized gene editing.
A new study shows that a group of neurons, previously thought to die in the course of development, in fact become incorporated into the brain’s cortex. This research has implications for understanding—and possibly treating—several brain disorders.
Scientists have found a new way to trawl blood samples for snippets of RNA released by tumors or diseased organs. The method might eventually help doctors diagnose and track a wide range of medical conditions.
For the first time, scientists have shown that a small cluster of cells in the human embryo dictates the fate of other embryonic cells. The discovery of this developmental “organizer” could advance research into many human diseases, and it suggests we have more in common with birds than meets the...
Out of over 900 universities from 55 different countries, Rockefeller tops a survey measuring the impact of university research publications, scoring the highest percentage of frequently cited scientific publications.
A new imaging tool makes it possible to track the firing of millions of brain cells in mice while the animals move about as normal. The method could help shed new light onto the neural processes that create behavior.
Ravetch receives the award for his groundbreaking work analyzing the immune system’s antibody response. He has worked for decades on the Fc fragment of the antibody molecule and its binding partners, known as Fc receptors.
Scientists have developed a new strategy to study the cells that host hidden reserves of dormant HIV, a step that may lead to new treatments that go beyond controlling the infection and instead aim to eradicate the virus entirely.
Among other superpowers, stem cells have a knack for fending off viruses like dengue and zika. Scientists have gained new insight into these curious defense strategies—knowledge they say could fuel the development of drugs against a range of diseases.
Thorne is recognized for his deft explanations that have drawn readers into the space-, time-, and mind-bending realm of Einstein’s ideas. The prize, which honors scientists as inspirational authors, will be presented on April 17.
A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.
Scientists have used cryo-electron microscopy to capture the very first snapshots of the large ribosomal subunit—part of the ribosome responsible for forging bonds between amino acids, the building blocks of proteins—coming together.
In mining soil for natural drugs, scientists have discovered a brand-new antibiotic potent against many bacteria. They hope it could be used to treat infections that cannot be stopped with existing drugs.
New research has helped explain what goes wrong in Aicardi-Goutières syndrome, a rare brain disorder. Patients with the disease have genetic abnormalities that may put their cells at risk of accidentally triggering an antiviral response.