The findings, which may have implications for a wide range of human diseases, suggest that nuclear pore complexes vary in structure and function even within a single nucleus.
Increasingly, hospitalized patients contract infections that evade current antibiotics including colistin, long used as a last treatment option. The discovery of a new colistin variant might make it possible to outmaneuver these pathogens.
This year's scientific endeavors included multiple attacks on SARS-CoV-2—and a lot more. Here are the most memorable science stories to come out of Rockefeller labs in 2021, from the benefits of brown fat to the pitfalls of modern IVF screening techniques.
Researchers found that the antibodies present in people who have had COVID or taken two doses of mRNA vaccine are inadequate against Omicron. But their protective ability increases significantly after a booster dose.
New research reveals how neurons in a fly's brain signal the direction in which the body is traveling. The cells appear to literally perform vector math in order to act as a biological compass.
Scientists have identified hundreds of llama-derived antibodies that potentially could be developed into a COVID treatment. They hope such a drug would be potent against different variants of the coronavirus, including Omicron.
A single cell has no nerves, yet it can feel and respond to mechanical forces such as pressure. Armed with new technologies, scientists are making headway in understanding how this sensory system operates.
Epidermal stem cells that hail from the hair follicle retain memories of their journey to the skin's surface. Those memories are a boon for wound repair, but may also contribute to chronic diseases and cancer.
In animal experiments, the structurally altered antibodies activated the immune system more effectively than those currently used in the clinic. They also proved to be more protective against the virus.
A major gift from Michael and Vikki Price marks the launch of an integrated effort to map and analyze the biological underpinnings of sociality and in turn better understand related disorders such as autism, depression, and schizophrenia.
Thanks to the existence of forgetful mice, scientists have gained clues into the process by which the brain forms short-term memories. They were even able to restore a mouse’s memory by genetic manipulation.
Prior infections appear to shield enteric neurons, preventing these key components of the body's "second brain" from dying off when future pathogens strike.
The September storm brought record rainfall which quickly overwhelmed drainage systems on campus and throughout the city. But the event did not cause widespread damage on campus thanks to improvements made nine years ago.
Farmers have a new enemy, a species of fruit fly that lays eggs in ripe produce. To help curtail the problem, scientists are getting to the bottom of how this trait arose in the course of evolution.
Darst receives the honor for pioneering research on RNA polymerase, the molecular machine that transcribes RNA from DNA. His work is leading to new knowledge about the transcription process, as well as to insights enabling development of urgent antibiotic and antiviral treatments.
Katalin Karikó discovered how to keep synthetic RNA from activating the innate immune system, paving the way for RNA vaccines including two for SARS-CoV-2.
Human cells can be coaxed into preventing certain enveloped viruses (including HIV, Ebola, and parainfluenza) from escaping their membranes in the lab, a finding that could lead to novel treatments for many viral diseases.
A new study finds that proteins known as linker histones control the complex coiling process that determines whether DNA will wind into long and thin chromosomes, made up of many small loops, or short and thick chromosomes with fewer large loops.
Uncovering the chemical composition of histones and innovating addiction treatment are only two of the accomplishments of the women scientists featured in a new photographic display.
A new pharmacy with clean room and other features makes it possible for pharmacists to prepare highly specialized compounds and sterile injectable drugs for use in clinical research.
