Researchers have found that the cells directing the very first steps of brain formation are not other neurons, as scientists have long assumed. They've also uncovered previously hidden molecular pathways that attract neurons into the brain.
Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease’s symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
Scientists have found that stem cells in the skin remember an injury, helping them close recurring wounds faster. The discovery could advance research and treatment of psoriasis and other inflammatory diseases.
Rockefeller University biologist Michael W. Young, who studies the biological clocks that regulate sleep, metabolism, and response to disease, is this year’s recipient of the Nobel Prize in Physiology or Medicine.
Within the oldest part of the brain, scientists have found cells in charge of controlling appetite and eating. The discovery could revitalize efforts to develop drugs for obesity that make us less hungry.
In the rats that roam New York City’s streets and tunnels, scientists have found a virus that resembles hepatitis C. They have used it to create the first animal model of the human disease, a breakthrough that potentially could yield a much-needed vaccine.
Allis has received the March of Dimes Prize in Developmental Biology. The award, given to investigators whose research offers hope for the prevention and treatment of birth defects and other infant diseases, honors Allis for his groundbreaking work on gene regulation.
Scientists have long seen parallels between healing wounds and growing tumors. In studying the molecular changes that occur within both, a research team has discovered a new cancer-fuelling mechanism that potentially could inform drug development.
The centromere region of chromosomes retains the same DNA from one generation to the next. Scientists have gained new insights into how it avoids being scrambled in normal cells, and how it becomes unstable in cancer.
Scientists have discovered a common mutation that might explain why some people have trouble going to sleep at night and getting up early. The gene alteration slows the internal biological clock that regulates our sleeping patterns.
In some people whose cognitive functions are weakened due to Alzheimer’s, the disease can be traced back to changes in the brain’s blood vasculature. Scientists have found that a protein involved in blood clotting and inflammation might offer a potential path to new drugs.
Two new technologies are helping scientists understand new aspects of organ and nervous system development in C. elegans. One allows them to image worms developing in a natural environment, while the other makes it possible to track single neurons as the worms grow.
New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by d...
As much as we try to avoid it, we are constantly sharing germs with those around us. But even when two people have the same infection, the resulting illnesses can be dramatically different—mild for one person, severe or even life-threatening for the other. Now, new research from The Rockefell...
As he opened this year’s Talking Science lecture, geneticist Jean-Laurent Casanova made a stark observation to his teenage audience: “If we had been here 150 years ago, about half of you would already have died.” The primary reason, he told the 350 high school students and 60 teachers present,...