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All animals, including humans, love sweet food. But if you’re someone who never turns down dessert under normal circumstances, try wolfing down six donuts as a scientific experiment. Even the moistest, most velvety piece of chocolate cake will seem a lot less appetizing—and you will likely eat l...

To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by scienti...

Jeffrey Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics, has won the 2016 Harrington Prize for Innovation in Medicine. The award, given by the American Society for Clinical Investigation and the Harrington Discovery Institute, recognizes physician-scientist...

Congratulations to our latest award winners: Cori Bargmann has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field. She is being honored for her work on the genetic and neural mech...

by Katherine Fenz, media relations manager Mutant mosquitoes Earlier this month, PBS Newshour featured Leslie Vosshall in a segment on the use of mutant mosquitoes to fight Zika and dengue fever. “Mosquitoes—especially the mosquitoes that are spreading Zika, dengue, and chikungunya...

In the ongoing arms race between pathogenic viruses and the cells they infect, each side needs every advantage it can get. One way wily viruses can get a leg up is by subverting the microRNAs (miRNAs) of their host. These miRNAs are small stretches of RNA made by host cells to regulate gene expre...

Barry Coller, vice president for medical affairs and physician-in-chief of The Rockefeller University Hospital, has won the 2016 Gill Award. The prize, given by the University of Kentucky Gill Heart Institute, recognizes lifelong achievements in the study of cardiovascular biology and disease. ...

One tornado alone can cause intense destruction, but the largest impact on both death rates and economic losses stems from “outbreaks,” in which six or more tornadoes occur within a limited time. New research from Joel Cohen, Abby Rockefeller Mauzé Professor and head of the Laboratory of Pop...

Can mutant mosquitoes be used to fight Zika and dengue fever? "'Ultimately, how cool would it be to have a cream that you put on your arm that has a probiotic, right, that makes you demagnetized as a mosquito magnet?' asks Leslie Vosshall."

What Iran May Be Able to Teach Us About Stem Cells "Now, there are opportunities for collaborations with non-Iranian scientists—which has Ali Brivanlou, who leads the Stem Cell Biology and Molecular Embryology lab at The Rockefeller University, intrigued about the possibilities."

Cori Bargmann, Torsten N. Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior, has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field...

by Diana Gitig, science writer Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response that bacteria and some other microbes use to defend...

Adult stem cells provide the body with a reservoir from which damaged or used up tissues can be replenished. In organs like the intestines and skin, which need constant rejuvenating, these stem cells are dividing frequently. But in other body structures, including the hair follicles, they are hel...

Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response bacteria and some other microbes use to defend themselves against viruses known as phag...

The molecular intricacies of hunger and satiety, pivotal for understanding metabolic disorders and the problem of obesity, are not yet fully understood by scientists. However, new research from The Rockefeller University reveals an important new component of the system responsible for regulating ...

The Options and Obstacles to Treating Heroin Addiction   "'Methadone became stigmatized almost immediately,' says Dr. Mary Jeanne Kreek of Rockefeller University. Kreek was part of the team that originally studied methadone as a potential treatment for opioid addiction in the 1960s. She notes tha...

by Katherine Fenz, media relations manager Tapping into human genetics holds great promise for understanding and treating disease, but there is still much to be learned. Scientists continue to have questions about how our DNA is altered in various afflictions, and how to effectively sort thr...

Congratulations to our latest award winners: Jean-Laurent Casanova has been recognized with the Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award is given by the American Society for Clinical Investigation, an honor society of phys...

Members of neuroscientist Cori Bargmann’s lab spend quite a bit of their time watching worms move around. These tiny creatures, Caenorhabditis elegans, feed on soil bacteria, and their very lives depend on their ability to distinguish toxic microbes from nutritious ones. In a recent study, Bargma...

To fight superbugs, scientists are turning toward antibodies   "'The bottom line is that the bacteria now develop resistance to anti-infectious agents faster than we can develop the anti-infectious agents,' says Dr. Jean-Laurent Casanova, a professor at Rockefeller University who studies how ge...

When seeking to protect themselves from viruses, some bacteria use a seemingly risky strategy: They wait until the invading virus has already begun to replicate. Research at The Rockefeller University shows how the microbes use two newly identified enzymes to fight off an infection even after del...

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, is the recipient of the 2016 Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award, given by the American Society for Clini...

Methylation’s Role in Eusocial Insect Behavior Questioned   "'Discovering that there is no evidence to support methylation as a reason why two ants can behave so differently was, on the one hand, a little sobering,' said study coauthor Daniel Kronauer of Rockefeller University in a press rele...

The exquisite social hierarchy of insect colonies has long fascinated scientists. Take two eggs—both contain identical genetic material, but while one becomes a sterile worker, the other may develop into a queen that can reproduce. Workers perform brood care and other crucial tasks that keep the ...

Stem cells work throughout our lives as a sort of handyman, repairing damaged tissues and renewing some normal ones, like the skin we shed. Scientists have come to understand much about how stem cells function when we are adults, but less is known about where these stem cells come from to begin w...

The Quest to Make a Better Mosquito Repellent   "It’s not easy for a human to find a mosquito that doesn’t want to be found, but a mosquito can locate us quite easily. It’s a human-seeking machine, sculpted by evolution to track the warmth of our bodies, the carbon dioxide in our breath, ...

The Quest to Make a Better Mosquito Repellent   "It’s not easy for a human to find a mosquito that doesn’t want to be found, but a mosquito can locate us quite easily. It’s a human-seeking machine, sculpted by evolution to track the warmth of our bodies, the carbon dioxide in our breath, ...

Congratulations to our latest award winners: Luciano Marraffini has been recognized with the Hans Sigrist Prize for his work developing a new approach to fight antibiotic resistance. The Hans Sigrist Prize recognizes work in a different academic field each year based on a decision by a faculty co...

Despite their bad reputations, the vast majority of mutations are not harmful. Even in very rare genetic disorders, only one or two genetic variations ­— out of tens of thousands — is actually the cause of disease. Distinguishing between harmful and harmless mutations has long been a challenge....

Since scientists have begun sequencing the genome of cancer cells, they have noticed a curious pattern. In many different types of cancers, there are cells in which a part of a chromosome looks like it has been pulverized, then put back together incorrectly, leading to multiple mutations. For yea...