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Displaying 224 of 2942 articles.
Sweet tooth? Flies have it too—and new research explains how they know what to eat and when to stop
All animals, including humans, love sweet food. But if you’re someone who never turns down dessert under normal circumstances, try wolfing down six donuts as a scientific experiment. Even the moistest, most velvety piece of chocolate cake will seem a lot less appetizing—and you will likely eat l...
Using magnetic forces to control neurons, study finds the brain plays key role in glucose metabolism
To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by scienti...
Jeffrey Friedman receives the 2016 Harrington Prize for Innovation in Medicine
Jeffrey Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics, has won the 2016 Harrington Prize for Innovation in Medicine. The award, given by the American Society for Clinical Investigation and the Harrington Discovery Institute, recognizes physician-scientist...
Awards, arrivals, and promotions
Congratulations to our latest award winners: Cori Bargmann has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field. She is being honored for her work on the genetic and neural mech...
Rockefeller scientists in the news
by Katherine Fenz, media relations manager Mutant mosquitoes Earlier this month, PBS Newshour featured Leslie Vosshall in a segment on the use of mutant mosquitoes to fight Zika and dengue fever. “Mosquitoes—especially the mosquitoes that are spreading Zika, dengue, and chikungunya...
A virus common among livestock depends on a microRNA to replicate
In the ongoing arms race between pathogenic viruses and the cells they infect, each side needs every advantage it can get. One way wily viruses can get a leg up is by subverting the microRNAs (miRNAs) of their host. These miRNAs are small stretches of RNA made by host cells to regulate gene expre...
Barry Coller receives the 2016 Gill Award for outstanding contributions to cardiovascular research
Barry Coller, vice president for medical affairs and physician-in-chief of The Rockefeller University Hospital, has won the 2016 Gill Award. The prize, given by the University of Kentucky Gill Heart Institute, recognizes lifelong achievements in the study of cardiovascular biology and disease. ...
New findings suggest severe tornado outbreaks are increasingly common
One tornado alone can cause intense destruction, but the largest impact on both death rates and economic losses stems from “outbreaks,” in which six or more tornadoes occur within a limited time. New research from Joel Cohen, Abby Rockefeller Mauzé Professor and head of the Laboratory of Pop...
In the News - PBS Newshour - Vosshall
Can mutant mosquitoes be used to fight Zika and dengue fever? "'Ultimately, how cool would it be to have a cream that you put on your arm that has a probiotic, right, that makes you demagnetized as a mosquito magnet?' asks Leslie Vosshall."
In the News - Mental Floss - Brivanlou
What Iran May Be Able to Teach Us About Stem Cells "Now, there are opportunities for collaborations with non-Iranian scientists—which has Ali Brivanlou, who leads the Stem Cell Biology and Molecular Embryology lab at The Rockefeller University, intrigued about the possibilities."
Cori Bargmann honored with the 2016 Scolnick Prize in Neuroscience
Cori Bargmann, Torsten N. Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior, has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field...
Luciano Marraffini, among the first scientists to plumb the workings of the CRISPR-Cas system, is promoted to associate professor
by Diana Gitig, science writer Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response that bacteria and some other microbes use to defend...
New research clarifies how stem cells get activated to produce new hair—and what happens when their regenerative powers wear out
Adult stem cells provide the body with a reservoir from which damaged or used up tissues can be replenished. In organs like the intestines and skin, which need constant rejuvenating, these stem cells are dividing frequently. But in other body structures, including the hair follicles, they are hel...
Luciano Marraffini, among the first scientists to plumb the workings of the CRISPR-Cas system, is promoted to associate professor
Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response bacteria and some other microbes use to defend themselves against viruses known as phag...
Metabolism protein found to also regulate feeding behavior in the brain
The molecular intricacies of hunger and satiety, pivotal for understanding metabolic disorders and the problem of obesity, are not yet fully understood by scientists. However, new research from The Rockefeller University reveals an important new component of the system responsible for regulating ...
In the News - PBS Frontline - Kreek
The Options and Obstacles to Treating Heroin Addiction   "'Methadone became stigmatized almost immediately,' says Dr. Mary Jeanne Kreek of Rockefeller University. Kreek was part of the team that originally studied methadone as a potential treatment for opioid addiction in the 1960s. She notes tha...
Rockefeller hosts the first New York City symposium on human genetics
by Katherine Fenz, media relations manager Tapping into human genetics holds great promise for understanding and treating disease, but there is still much to be learned. Scientists continue to have questions about how our DNA is altered in various afflictions, and how to effectively sort thr...
Awards, arrivals, and promotions
Congratulations to our latest award winners: Jean-Laurent Casanova has been recognized with the Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award is given by the American Society for Clinical Investigation, an honor society of phys...
Scientists learn how young brains form lifelong memories by studying worms’ food choices
Members of neuroscientist Cori Bargmann’s lab spend quite a bit of their time watching worms move around. These tiny creatures, Caenorhabditis elegans, feed on soil bacteria, and their very lives depend on their ability to distinguish toxic microbes from nutritious ones. In a recent study, Bargma...
In the News - Newsweek - Casanova
To fight superbugs, scientists are turning toward antibodies   "'The bottom line is that the bacteria now develop resistance to anti-infectious agents faster than we can develop the anti-infectious agents,' says Dr. Jean-Laurent Casanova, a professor at Rockefeller University who studies how ge...
A newly discovered form of immunity helps explain how bacteria fight off viruses
When seeking to protect themselves from viruses, some bacteria use a seemingly risky strategy: They wait until the invading virus has already begun to replicate. Research at The Rockefeller University shows how the microbes use two newly identified enzymes to fight off an infection even after del...
Jean-Laurent Casanova honored with the Korsmeyer Award
Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, is the recipient of the 2016 Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award, given by the American Society for Clini...
In the News - The Scientist - Kronauer
Methylation’s Role in Eusocial Insect Behavior Questioned   "'Discovering that there is no evidence to support methylation as a reason why two ants can behave so differently was, on the one hand, a little sobering,' said study coauthor Daniel Kronauer of Rockefeller University in a press rele...
New findings challenge popular explanation for why a social insect becomes a worker or queen
The exquisite social hierarchy of insect colonies has long fascinated scientists. Take two eggs—both contain identical genetic material, but while one becomes a sterile worker, the other may develop into a queen that can reproduce. Workers perform brood care and other crucial tasks that keep the ...
Study identifies signals that make early stem cells
Stem cells work throughout our lives as a sort of handyman, repairing damaged tissues and renewing some normal ones, like the skin we shed. Scientists have come to understand much about how stem cells function when we are adults, but less is known about where these stem cells come from to begin w...
In the News - The Atlantic - Vosshall
The Quest to Make a Better Mosquito Repellent   "It’s not easy for a human to find a mosquito that doesn’t want to be found, but a mosquito can locate us quite easily. It’s a human-seeking machine, sculpted by evolution to track the warmth of our bodies, the carbon dioxide in our breath, ...
In the News - The Atlantic - Vosshall
The Quest to Make a Better Mosquito Repellent   "It’s not easy for a human to find a mosquito that doesn’t want to be found, but a mosquito can locate us quite easily. It’s a human-seeking machine, sculpted by evolution to track the warmth of our bodies, the carbon dioxide in our breath, ...
Awards, arrivals, and promotions
Congratulations to our latest award winners: Luciano Marraffini has been recognized with the Hans Sigrist Prize for his work developing a new approach to fight antibiotic resistance. The Hans Sigrist Prize recognizes work in a different academic field each year based on a decision by a faculty co...
Researchers develop gene-filtering tool to identify disease-causing mutations
Despite their bad reputations, the vast majority of mutations are not harmful. Even in very rare genetic disorders, only one or two genetic variations ­— out of tens of thousands — is actually the cause of disease. Distinguishing between harmful and harmless mutations has long been a challenge....
Experiments explain the events behind molecular ‘bomb’ seen in cancer cells
Since scientists have begun sequencing the genome of cancer cells, they have noticed a curious pattern. In many different types of cancers, there are cells in which a part of a chromosome looks like it has been pulverized, then put back together incorrectly, leading to multiple mutations. For yea...
Luciano Marraffini receives the Hans Sigrist Prize for work on antibiotic resistance
Luciano Marraffini, assistant professor and head of the Laboratory of Bacteriology, has been recognized with the Hans Sigrist Prize for his work developing a new approach to combat antibiotic resistance. This Swiss award, bestowed by the University of Bern, specifically honors Marraffini for mani...
Mosquitoes are tuned to seek out temperatures that match warm-blooded hosts
Many animals gravitate towards heat, most often to regulate their own body temperatures. In rare cases, certain species—ticks, bedbugs, and some species of mosquitoes—seek out heat for food. For female mosquitoes, finding heat is essential for survival, as they need to feast on warm-blooded prey...
Researchers discover new aspect of gene regulation and a possible target for cancer drugs
There are about 20,000 genes in the human genome, but not all are used in all cells at all times. At any given moment, a cell is converting only roughly half its genes into proteins. And of those active genes, about 75 percent are regulated by a process known as “RNA polymerase pausing.” This...
Study suggests new way to help the immune system fight off sleeping sickness parasite
Some infectious diseases are particularly difficult to treat because of their ability to evade the immune system. One such illness, African sleeping sickness, is caused by the parasite Trypanosoma brucei, transmitted by the tsetse fly, and is fatal if left untreated. The trypanosome parasite is t...
New research helps to explain how temperature shifts the circadian clock
For many living things, a roughly 24-hour internal clock governs the rhythms of life—everything from sleep in animals, to leaf opening in plants and reproduction in bread mold. Scientists have come to understand much about this internal time-keeping system, but one important aspect, its complex r...
Study reveals new mechanism in nicotine addiction
Part of the reason people find smoking difficult to quit is that each time they have a cigarette, feelings of craving, irritability and anxiety melt away. This component of addiction is known as negative reward and is controlled in part by a region of the brain called the habenula. The neurotrans...
Rockefeller’s newest faculty member investigates how antibodies are made
When a pathogen invades the body, the immune system responds by producing proteins called antibodies that are precisely targeted at the invader. Gabriel Victora, an immunologist who studies how these finely tuned antibodies are generated, is the most recent addition to Rockefeller’s tenure-track ...
Rockefeller’s newest faculty member investigates how antibodies are made
by Katherine Fenz, media relations manager When a pathogen invades the body, the immune system responds by producing antibodies that are precisely targeted at the invader. Gabriel Victora, an immunologist who studies how these finely tuned antibodies are generated, is the most recent addition t...
Awards, arrivals, and promotions
Congratulations to our latest award winners: Jesse Ausubel has been awarded an American Geographical Society honorary fellowship. The fellowship recognizes an individual who has made significant contributions to the field of geography. Certificates of this honor will be presented during the so...
DNA strands often “wiggle” as part of genetic repair
Sometimes, the molecules that make up life exhibit strange behavior. For instance, in simple organisms such as yeast, when genetic material becomes damaged, the affected DNA strands increase their motion, waving about inside the cell like a sail unfurled. Over the years, scientists have seen more...
Researchers identify potential new leukemia drug target
New treatment options are badly needed for acute myeloid leukemia, a relatively rare form of cancer. The malignancy begins in the bone marrow, and from there can spread rapidly to the bloodstream, depriving the body of the essential blood cells that carry oxygen and fight infections. Now, new wor...
Jean-Laurent Casanova elected to the National Academy of Medicine
Jean-Laurent Casanova, who investigates genetic vulnerability to infectious diseases among children, has been elected to the U.S. National Academy of Medicine, the health and medicine arm of the National Academy of Sciences. Casanova is professor and head of the St. Giles Laboratory of Human Gen...
Helmsley Trust renews $15 million grant for novel digestive disorders research
The Leona M. and Harry B. Helmsley Charitable Trust has awarded a new three-year, $15-million grant to The Rockefeller University to help support the interdisciplinary Center for Basic and Translational Research on Disorders of the Digestive System. Established in 2012 with an initial $15-million...
Helmsley Trust renews $15 million grant for novel digestive disorders research
by Wynne Parry, Science Writer The Leona M. and Harry B. Helmsley Charitable Trust has awarded a new three-year, $15-million grant to The Rockefeller University to help support the interdisciplinary Center for Basic and Translational Research on Disorders of the Digestive System. Established in 2...
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