Brief bursts of intense exercise trigger a molecular response linked to a lower risk of cardiovascular and metabolic disease and that are associated with slower biological aging.
Rockefeller's Birsoy and Vinogradova labs teamed up to study how cancer cells rewire their metabolism, and how these changes could be targeted therapeutically.
A new protein-tracing platform reveals how fat and liver cells communicate during fasting, inflammation, and obesity, and links many of those signals to human disease.
Scientists knew that obesity raises the risk of hypertension. Now Paul Cohen's team has uncovered the mechanism—and the enzyme—that explains how fat can stiffen blood vessels and drive blood pressure upward.
New study shows that beige fat suppresses an enzyme that promotes high blood pressure, revealing a new molecular pathway and a potential target for future precision therapies.
Researchers discovered that a crucial first step in the signaling system operates differently than previously thought, an insight that could lead to the next generation of treatments.
