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Displaying 87 of 2813 articles.

Telomere shortening protects against cancer

Researchers have found the first evidence that telomere shortening is not just a sign of aging, but a key component of the body's cancer prevention system.

Rockefeller's Charles M. Rice honored with Nobel Prize for research that contributed to a cure for hepatitis C

Rice will receive the 2020 Nobel Prize in Physiology or Medicine for research that led to a cure for hepatitis C, a viral disease affecting 170 million people worldwide. His lab worked on the virus for three decades and became the first to produce a version of it that could be grown and studied i...

Cancer cells use nerve-cell tricks to spread from one organ to the next

New research suggests that breast and lung tumors metastasize by hijacking a neural signaling pathway, potentially opening the door to better diagnostics and treatments.

How mechanical forces nudge tumors toward malignancy

Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the di...

Unique mutation reveals a new role for well-known DNA-repair gene

The discovery of a rare mutation in BRCA2, commonly known as the breast cancer gene, has shed new light on how cells safeguard their genetic material.
 

Study reveals first evidence inherited genetics can drive cancer’s spread

Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates our own pre-existing genetics.

Rockefeller grants commercial license for the development of new HIV drugs

The novel compounds are based on so-called broadly neutralizing antibodies, molecules that make rare people's immune systems capable of fighting HIV. They could potentially yield new treatment and prevention approaches benefitting people around the world, including in developing countries.

Small containers inside cells might offer new targets for cancer treatment

For reasons that have long been unclear, cells stop dividing when the pH rises inside tiny cellular compartments called lysosomes. Now scientists have found an explanation for this phenomenon, with potential implications for drug development.

Researchers discover a new mechanism in childhood kidney cancer

A problem in reader proteins that identify which gene is up for expression may cause normal cells to turn malignant during development.

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Study sheds new light on how epigenetic events might spur disease

Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.