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Displaying 142 of 2778 articles.

Scientists develop new method that predicts vulnerability to stress

Researchers have identified a set of biological factors in mice that seem to determine one's ability to bounce back from a traumatic event, and provide preliminary evidence that a naturally-occurring substance may help boost resiliency in the face of stressful situations.

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Study sheds new light on how epigenetic events might spur disease

Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.

The pathway to Parkinson’s takes a surprising twist

A new study finds that neurons affected in Parkinson’s disease can shut down without fully dying, allowing them to also switch off neighboring cells. The findings might give scientists a better understanding of how the condition wreaks havoc in the brain, as well as ideas for new treatments.

C. David Allis elected to the National Academy of Medicine

Allis, whose pioneering research established that enzymes that modify histone proteins, which package DNA in the nucleus, regulate gene expression, has been elected to the National Academy of Medicine.

New research raises prospect of better anti-obesity drugs

Scientists have found a group of brain cells that influence body mass in two ways, by controlling how much we eat as well as how much energy we burn. The findings could lead to new drugs to help people shed weight.

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New molecular diagnostics test could help guide lupus treatments

A tool that detects glitches in gene expression could help doctors tailor treatments for lupus-related kidney damage.

New compounds could be used to treat autoimmune disorders

In autoimmune disorders, the body’s defense system erroneously attacks normal cells, leading to serious health problems. Researchers have developed new molecules that potentially could be used to treat many of these conditions.

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Researchers find genetic link to tuberculosis

Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.

New hope for treating a childhood brain cancer

Recent research has shown that a drug known as MI-2 can kill cells that cause a fatal brain cancer. But only now have scientists been able to explain how the compound works: by targeting cholesterol production in tumors.

New approach to treating gastrointestinal disease patches up leaky intestines

Researchers have discovered a new compound that helps fortify the intestine's inner lining, which becomes porous in inflammatory bowel diseases.