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How antibodies from llamas may lead to COVID-19 treatment

Llamas make antibodies that are much smaller than their human counterparts, yet still potent. Scientists hope that future drugs based on these molecules could provide new weapons against SARS-CoV-2.

Unique mutation reveals a new role for well-known DNA-repair gene

The discovery of a rare mutation in BRCA2, commonly known as the breast cancer gene, has shed new light on how cells safeguard their genetic material.
 

Study reveals first evidence inherited genetics can drive cancer’s spread

Scientists have long struggled to understand what drives a tumor to seed itself elsewhere in the body. New research implicates our own pre-existing genetics.

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

The condition resembles a rare childhood illness, Kawasaki disease. Researchers are analyzing blood samples to find genetic clues to what might be causing it.

The gene hunt to explain why some young, healthy people die from COVID-19

People under 50 without preexisting conditions typically develop mild symptoms of coronavirus infection—but there are exceptions. Researchers are working to identify rare genetic variations that may explain why some in this group have succumbed to the disease.

Rockefeller scientists launch a broad range of studies into novel coronavirus

Over 130 scientists in 18 labs are conducting research to advance the development of new, urgently needed approaches for the prevention and treatment of COVID-19.

Small containers inside cells might offer new targets for cancer treatment

For reasons that have long been unclear, cells stop dividing when the pH rises inside tiny cellular compartments called lysosomes. Now scientists have found an explanation for this phenomenon, with potential implications for drug development.

Researchers discover a new mechanism in childhood kidney cancer

A problem in reader proteins that identify which gene is up for expression may cause normal cells to turn malignant during development.

Scientists develop new method that predicts vulnerability to stress

Researchers have identified a set of biological factors in mice that seem to determine one's ability to bounce back from a traumatic event, and provide preliminary evidence that a naturally-occurring substance may help boost resiliency in the face of stressful situations.

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Study sheds new light on how epigenetic events might spur disease

Research that began with the analysis of two developmental syndromes ultimately helped scientists understand how diverse epigenetic mechanisms can combine to drive tissue overgrowth in cancer.