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Günter Blobel, a Nobel laureate who redefined cell biology, has died

Günter Blobel, a Nobel Prize-winning Rockefeller biologist who discovered the mechanisms by which proteins are targeted for delivery to specific locations within cells, died February 18 at 81.

Uncovering the early origins of Huntington’s disease

The symptoms of Huntington’s typically appear in middle age, but the disease may in fact originate much earlier. New research shows that a patient’s neural abnormalities may arise already during embryonic development—suggesting that treating the disease early may be beneficial.

New immunotherapy approach boosts body’s ability to destroy cancer cells

A new treatment may help cancer patients who don't respond to traditional immunotherapy. Findings from the first-ever clinical trial reveal that it is effective in activating immune cells that kill cancer cells.

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In brief: Variation between strains may account for differences in people’s vulnerability to infection

New research shows that subtle differences between bacterial strains may cause dramatic differences in outcome between people infected with the same microbe.

3D imaging of fat reveals potential targets for new obesity treatments

With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.

In brief: New clues about how cells restart stalled replication

Scientists studying the cell’s DNA-copying machinery have discovered a molecular mechanism that helps reactivate it should it stop prematurely. Its function may prevent genetic errors like those that cause cancer.

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In brief: A close look at how HIV-fighting proteins slow the virus down

A new study sheds light on how the body fights back against HIV by mutating the viral DNA.

New study points the way to therapy for rare cancer that targets the young

Scientists have engineered a mouse model to study a rare and often-fatal form of liver cancer. They’ve used it to clarify what drives these tumors at the molecular level, and discover new drug concepts.

In the fight against viral infection, spelling counts

Scientists have discovered a peculiarity in the genetic code of HIV that might explain how this and other viruses evolved ways to dodge our immune system. The findings could make it possible to develop safer vaccines.

Targeting a single protein might treat a broad range of viruses

Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.