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In Brief

In brief: Variation between strains may account for differences in people’s vulnerability to infection

New research shows that subtle differences between bacterial strains may cause dramatic differences in outcome between people infected with the same microbe.
neural projections within fat tissue
Science News

3D imaging of fat reveals potential targets for new obesity treatments

With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.
Science News

In brief: New clues about how cells restart stalled replication

Scientists studying the cell’s DNA-copying machinery have discovered a molecular mechanism that helps reactivate it should it stop prematurely. Its function may prevent genetic errors like those that cause cancer.
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In Brief

In brief: A close look at how HIV-fighting proteins slow the virus down

A new study sheds light on how the body fights back against HIV by mutating the viral DNA.
New study points the way to therapy for rare cancer that targets the young
Science News

New study points the way to therapy for rare cancer that targets the young

Scientists have engineered a mouse model to study a rare and often-fatal form of liver cancer. They’ve used it to clarify what drives these tumors at the molecular level, and discover new drug concepts.
A human cell (green) infected with HIV (red)
Science News

In the fight against viral infection, spelling counts

Scientists have discovered a peculiarity in the genetic code of HIV that might explain how this and other viruses evolved ways to dodge our immune system. The findings could make it possible to develop safer vaccines.
Measles virus is suppressed
Science News

Targeting a single protein might treat a broad range of viruses

Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
Fragile X brain
Science News

Potential new treatment for Fragile X targets one gene to affect many

Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease’s symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
CA3 neurons
Science News

Stress has dramatically different effects on male and female mouse brains

Scientists have found unexpected differences in how male and female mice respond to stress. Their findings are raising big questions about sex discrepancies in the brain and their impact on neuropsychiatric disease.
Titia de Lange
Awards and Honors

Titia de Lange to receive 2017 Rosenstiel Award

de Lange is honored for her elucidation of the mechanism of telomere protection and the maintenance of genome stability.
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