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Displaying 163 of 2812 articles.
Science News

A compound that stops cells from making protein factories could lead to new antifungal drugs

Tiny, abundant biological factories, known as ribosomes, produce the cell’s most fundamental building material: protein. If ribosomes don’t work, cells can’t divide—and this can be an advantage for scientists seeking to develop drugs that target invading organisms, such as pathogenic fungi. ...
Awards and Honors

Four Rockefeller scientists named 2016 HHMI Faculty Scholars

Four Rockefeller University scientists—Daniel Kronauer, Luciano Marraffini, Agata Smogorzewska, and Sohail Tavazoie—have been named Howard Hughes Medical Institute Faculty Scholars. The Faculty Scholars program, a new collaboration between HHMI, the Simons Foundation, and the Bill & Melinda Gate...
Science News

Scientists uncover a clever ranking strategy bacteria use to fight off viruses

Like humans, bacteria come under attack from viruses and rely on an immune system to defend themselves. A bacterial immune system known as CRISPR helps microbes “remember” the viruses they encounter and more easily fend them off in the future. Since researchers first discovered CRISPR in the mid...
Awards and Honors

Charles M. Rice wins Lasker Award for groundbreaking work on the hepatitis C virus

Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology and head of the Laboratory of Virology and Infectious Disease, has been honored with the 2016 Lasker-DeBakey Clinical Medical Research Award, the country’s most prestigious science prize. Rice shares the award with Ralf F....
Science News

Four postdocs honored with 2016 Tri-Institutional Breakout Awards

NEW YORK, NY—Four young life scientists from Memorial Sloan Kettering Cancer Center, The Rockefeller University, and Weill Cornell Medicine are the winners of the 2016 Tri-Institutional Breakout Awards for Junior Investigators. The awards, established last year by three winners of the 2013 Breakt...
Science News

New antibody drug continues to show promise for treatment of HIV

Great strides have been made in recent years to develop treatment options for HIV, and the disease can now be controlled with anti-retroviral drugs. But a cure remains elusive and current medications have limitations: they must be taken daily, for life, and can cause long-term complications. Now,...
Awards and Honors

Postdoc John Maciejowski wins 2016 Regeneron Prize for Creative Innovation

John Maciejowski, a postdoctoral fellow in Titia de Lange’s Laboratory of Cell Biology and Genetics, has received the 2016 Regeneron Prize for Creative Innovation. The award, given by Regeneron Pharmaceuticals, Inc., recognizes innovative young scientists based on proposals they submit that have ...
Awards and Honors

Michel C. Nussenzweig honored with the 2016 Robert Koch Award

Michel C. Nussenzweig, Zanvil A. Cohn and Ralph M. Steinman Professor and head of the Laboratory of Molecular Immunology, has won the 2016 Robert Koch Award. Nussenzweig will share the €100,000 prize, given by the Robert Koch Foundation of Germany, with Alberto Mantovani from Humanitas University...
Science News

Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates

There was a time when Thomas Huber, a molecular biologist at The Rockefeller University, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar’s Laboratory of Chemical Biology and Signal Transduction, became curious about ...
Science News

New method gives scientists a better look at how HIV infects and takes over its host cells

Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have long probed this process for insights into biology and disease, but essential details still remain out of reach. A new approach, developed by a team of researchers led by The Rock...
Campus News

35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller

by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...
Science News

Scientists find evidence that cancer can arise from changes in the proteins that package DNA

A mutation that affects the proteins that package DNA—without changing the DNA itself—can cause a rare form of cancer, according to new findings in this week’s Science from researchers at Rockefeller University. The mutation is present in histones, the protein scaffolding around which DNA w...
Awards and Honors

C. David Allis receives the 2016 Gruber Genetics Prize

C. David Allis, Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics, has won the 2016 Gruber Genetics Prize. He shares the $500,000 award with Michael Grunstein of the University of California, Los Angeles. The award, given by The Gruber Foundation, reco...
Science News

Antibody therapy opens door to potential new treatment for HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades. But this therapy has drawbacks...
Science News

A central clock runs the cell division cycle

Each time a cell divides, it replicates its DNA once, then separates the two copies from each other and splits into two daughter cells. The event is intricately coordinated and was long known to be under the influence of cyclins—an aptly named group of proteins whose levels go up and down as the ...
Awards and Honors

Nathaniel Heintz and Stanislas Leibler elected to the National Academy of Sciences

Nathaniel Heintz, James and Marilyn Simons Professor and head of the Laboratory of Molecular Biology, and Stanislas Leibler, Gladys T. Perkin Professor and head of the Laboratory of Living Matter, have been elected to the U.S. National Academy of Sciences. They are among 84 new national and 21 ne...
Awards and Honors

Charles Rice wins Belgium’s highest scientific prize

Charles M. Rice, Maurice R. and Corinne P. Greenberg Professor in Virology and head of the Laboratory of Virology and Infectious Disease, has been honored with the 2016 InBev-Baillet Latour Health Prize for his work on the hepatitis C virus. Queen Mathilde of Belgium presented Rice with the prize...

In the News - The New Yorker - Allis

Same but Different: How epigenetics can blur the line between nature and nurture "Allis walked me to his lab, a fluorescent-lit space overlooking the East River, divided by wide, polished-stone benches. A mechanical stirrer, whirring in a corner, clinked on the edge of a glass beaker. 'Two featur...
Science News

Mice engineered with rare kidney disease provide new insights about how cells repair broken DNA

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell—sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have ...
Science News

A common brain cell shapes the nervous system in unexpected ways

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them—similarly to how the plastic casing of an electric cable insulates the copper wire within—allowing electrical and chemical impulses to travel faster. In the past, neuroscientists considered ...
Science News

A newly discovered way for cells to die

Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for termination. This cell helps determine the shape of the gonad in male worms—and then it dies, after two days...
Science News

Parasites reveal how evolution has molded an ancient nuclear structure

Long before animals evolved from sponges, and before plants evolved out of algae, there was a pivotal event that allowed complex, multicellular organisms to arise: the development of the nucleus in single-celled organisms. Eukaryotes, one of the three main branches of living organisms, are define...
Campus News

Awards, arrivals, and promotions

Congratulations to our latest award winners: Cori Bargmann has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field. She is being honored for her work on the genetic and neural mech...
Science News

A virus common among livestock depends on a microRNA to replicate

In the ongoing arms race between pathogenic viruses and the cells they infect, each side needs every advantage it can get. One way wily viruses can get a leg up is by subverting the microRNAs (miRNAs) of their host. These miRNAs are small stretches of RNA made by host cells to regulate gene expre...
Campus News

Luciano Marraffini, among the first scientists to plumb the workings of the CRISPR-Cas system, is promoted to associate professor

by Diana Gitig, science writer Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response that bacteria and some other microbes use to defend...
Science News

New research clarifies how stem cells get activated to produce new hair—and what happens when their regenerative powers wear out

Adult stem cells provide the body with a reservoir from which damaged or used up tissues can be replenished. In organs like the intestines and skin, which need constant rejuvenating, these stem cells are dividing frequently. But in other body structures, including the hair follicles, they are hel...
Campus News

Luciano Marraffini, among the first scientists to plumb the workings of the CRISPR-Cas system, is promoted to associate professor

Rockefeller University microbiologist Luciano Marraffini, head of the Laboratory of Bacteriology, has been promoted to associate professor. He studies the CRISPR-Cas system, which is part of an immune response bacteria and some other microbes use to defend themselves against viruses known as phag...
Campus News

Awards, arrivals, and promotions

Congratulations to our latest award winners: Jean-Laurent Casanova has been recognized with the Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award is given by the American Society for Clinical Investigation, an honor society of phys...
Science News

A newly discovered form of immunity helps explain how bacteria fight off viruses

When seeking to protect themselves from viruses, some bacteria use a seemingly risky strategy: They wait until the invading virus has already begun to replicate. Research at The Rockefeller University shows how the microbes use two newly identified enzymes to fight off an infection even after del...
Science News

Study identifies signals that make early stem cells

Stem cells work throughout our lives as a sort of handyman, repairing damaged tissues and renewing some normal ones, like the skin we shed. Scientists have come to understand much about how stem cells function when we are adults, but less is known about where these stem cells come from to begin w...
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