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Displaying 176 of 2891 articles.

Brain study finds a molecular “off” switch for nicotine craving

In findings that might lead to better smoking-cessation tools, scientists have shown that manipulating a specific brain receptor can alter a mouse’s nicotine sensitivity.

Unique mutation reveals a new role for well-known DNA-repair gene

The discovery of a rare mutation in BRCA2, commonly known as the breast cancer gene, has shed new light on how cells safeguard their genetic material.
 

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3D imaging of blood vessels could shed new light on cardiovascular disease

The new imaging technique enables researchers to construct a comprehensive image of blockages and other vascular injuries.

Rockefeller scientists launch a broad range of studies into novel coronavirus

Over 130 scientists in 18 labs are conducting research to advance the development of new, urgently needed approaches for the prevention and treatment of COVID-19.

How skin cells embark on a swift yet elaborate death

Scientists have identified the mechanism that allows skin cells to sense changes in their environment, and very quickly respond to reinforce the skin's outermost layer. The findings provide insight into how errors in this process might lead to skin conditions like psoriasis.  

Rockefeller grants commercial license for the development of new HIV drugs

The novel compounds are based on so-called broadly neutralizing antibodies, molecules that make rare people's immune systems capable of fighting HIV. They could potentially yield new treatment and prevention approaches benefitting people around the world, including in developing countries.

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Neuron-like activity detected in an unforeseen place

Scientists have identified a particular type of skin cell that looks and behaves similar to a nerve cell, prompting new questions about the body's biggest organ.

Small containers inside cells might offer new targets for cancer treatment

For reasons that have long been unclear, cells stop dividing when the pH rises inside tiny cellular compartments called lysosomes. Now scientists have found an explanation for this phenomenon, with potential implications for drug development.

Researchers discover a new mechanism in childhood kidney cancer

A problem in reader proteins that identify which gene is up for expression may cause normal cells to turn malignant during development.

Neurodegenerative diseases may be caused by molecular transportation failures inside neurons

Protein clumps are routinely found in the brains of patients with neurodegenerative diseases. Now researchers find a link between this buildup and the intracellular movement of proteasomes, molecular machines tasked with degrading protein waste inside cells.