Instruments and Techniques
The DDRC has the capability to support high throughput screening of cellular and biochemical assays using absorbance, fluorescence, fluorescence anisotropy, time-resolved fluorescence, time-gated fluorescence resonance energy transfer, luminescent oxygen channeling and bioluminescence. The bioassay targets can include ion channels, receptors, enzymes, proteins, signaling pathways and cellular processes. Additionally, measurements of drug occupancy are supported with a variety of biophysical techniques.
Initiating a project with us
If you are interested in setting up an HTS/drug discovery project or utilizing our instruments, please contact ddrc@rockefeller.edu. Assay development and screening typically require a significant financial and time commitment and advance discussions are needed to prepare for the project. This resource center is a shared facility supported by Weill-Cornell Medical College and Rockefeller University, and we welcome clients from those institutions. Due to a high demand for our services, we can accept projects from outside institutions only on a case-by-case basis. The DDRC does not currently support research in conjunction with for-profit entities.