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Fisher Drug Discovery Resource Center

The Fisher Drug Discovery Resource Center’s (DDRC) objective is to offer resources that facilitate the discovery of new compounds capable of modulating specific drug targets for therapeutic purposes. Furthermore, it aims to assist in understanding the mechanisms of action of these compounds and establishing the connection between their structure and activity. Ultimately, our goal is to publish or patent novel findings that contribute to global drug discovery efforts.

The center staff guides and supports our researchers in drug discovery by improving the efficiency of their bioassays, identifying compounds for drug refinement and development, understanding the targets for drugs, and in providing technologies for the measurement of drug/receptor interactions. The center has a collection of 500,000 drug-like compounds, along with semi-automated liquid pipetting devices, and bioassay instruments for supporting drug discovery programs.  The center has expertise and instrumentation for studies of the interactions of drugs with their targets. (RRID:SCR_020985)

The DDRC supports investigations in the following areas:

    • developing assay cascades for drug discovery projects
    • miniaturized assay development
    • high-throughput screening
    • identifying compounds for drug discovery or biomedical research
    • measuring the kinetics and thermodynamics of biomolecular interactions

Fisher Drug Discovery Resource Center Lecture, June 1, 2022

Meeting Recording:  KJUW91Vou-WhkgHfc6ssTIT1mu6UcE.5Wx3SS_Db-6ijxTQ

Access Passcode: X*wnCij1

Initiating a project with us

If you are interested please contact Drug discovery typically requires a significant financial and time commitment and advance discussions are needed to prepare. This resource center is a shared facility supported by Weill-Cornell Medical College and The Rockefeller University, and we welcome clients from those institutions. Due to a high demand for our services, we can accept projects from outside institutions only on a case-by-case basis. The DDRC does not currently support research in conjunction with for-profit entities.

The high-throughput screening process


The Rockefeller University
Box 203
1230 York Ave
New York, NY 10065

Fisher Drug Discovery Resource Center
Bronk Laboratory
DWB Room 216