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Recent computer attacks on campus target Macs, e-mail

by LESLIE CHURCH It’s not just biologists who are studying infection at Rockefeller. Computer security experts based in the IT Pavilion have been kept busy in recent months managing outbreaks of viruses and other malware on campus computers.     In June more than a dozen people on campus fe...

Cell 149: 1565-1577 (June 22, 2012)

Cell 149: 1565-1577 Tiki1 Is Required for Head Formation via Wnt Cleavage-Oxidation and Inactivation Xinjun Zhang, Jose Garcia Abreu, Chika Yokota, Bryan T. MacDonald, Sasha Singh, Karla Loureiro Almeida Coburn, Seong-Moon Cheong, Mingzi M. Zhang, Qi-Zhuang Ye, Howard C. Hang, Hanno Steen and Xi He

Employees honored for longtime service to university

Members of the Rockefeller faculty and staff were recognized for their service to the university with two recent events. The Employee Recognition Cocktail Reception in February honored employees who had worked at the university for 20 and 25 years. Fifty-nine employees celebrated 20 years of serv...

Genome Center to operate at Rockefeller in interim

by LESLIE CHURCH The New York Genome Center (NYGC), the nonprofit institution set to become one of the largest bioinformatics and genomics facilities in North America, is launching its pilot lab operations at The Rockefeller University while a search is conducted for a permanent facility. Rockef...

Thomas P. Maniatis elected to Board

by LESLIE CHURCH The university Board of Trustees elected Thomas P. Maniatis as its newest member at its spring meeting on March 14, bringing the total number of trustees to 43. Dr. Maniatis is the Isidore S. Edelman Professor and Chairman of the department of biochemistry and molecular biophysi...

Milestones

Awarded: Jesse H. Ausubel, the 2012 National Ocean Champion Award, presented by the Urban Coast Institute of Monmouth University in New Jersey, for his contributions to marine science and management. Mr. Ausubel joins a distinguished group of awardees, including Jean-Michel Cousteau, who won in 2...

In the news

Peak planet: Are we starting to consume less?   “That leads demographer Joel Cohen to predict that ‘many of us may live to see population peak in the middle of this century.’ If so, that would fulfill the first necessary condition to begin to reduce our demands on the planet.” “An analy...

Proceedings of the National Academy of Sciences USA online: June 20, 2012

Proceedings of the National Academy of Sciences USA online: June 20, 2012 Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement Fubin Li and Jeffrey V. Ravetch

Proceedings of the National Academy of Sciences USA online: June 18, 2012

Proceedings of the National Academy of Sciences USA online: June 18, 2012 Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation Alexander L. Kovalchuk, Camilo Ansarah-Sobrinho, Ofir Hakim, Wolfgang Resch, Helena Tolarová, Wendy  Duboi...

Rockefeller’s 54th convocation awards Ph.D.s to 40 graduating students

The Rockefeller University will award doctoral degrees to 40 students at its convocation ceremony today. Additionally, two esteemed researchers will receive honorary doctor of science degrees: James E. Darnell Jr., Vincent Astor Professor Emeritus and head of the Laboratory of Molecular Cell Biol...

Vanessa Ruta named Pew Scholar in the Biomedical Sciences

Vanessa Ruta, head of the Laboratory of Neurophysiology and Behavior at The Rockefeller University, has been chosen as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts. Ruta is among twenty-two early-career researchers who are being honored for showing outstanding promise in ...

Cancer Cell 21: 765-766 (June 12, 2012)

Cancer Cell 21: 765-766 Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells Teresa Davoli and Titia de Lange

Proceedings of the National Academy of Sciences USA online: June 11, 2012

Proceedings of the National Academy of Sciences USA online: June 11, 2012 Dynamics of TGF-β signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4 Aryeh Warmflash, Qixiang Zhang, Benoit Sorre, Alin Vonica, Eric D. Siggia and Ali H. Br...

Science online: June 7, 2012

Science online: June 7, 2012 dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway Jeannette M. Osterloh, Jing Yang, Timothy M. Rooney, A. Nicole Fox, Robert Adalbert, Eric H. Powell, Amy E. Sheehan, Michelle A. Avery, Rachel Hackett, Mary A. Logan, Jennifer M. MacDonald,...

Cornelia Bargmann receives Kavli Prize in Neuroscience

Cornelia Bargmann, Torsten N. Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior, is the recipient of the 2012 Kavli Prize in Neuroscience, the Norwegian Academy of Science and Letters announced today. Bargmann, who is also an investigator at the How...

Cell 149: 1164-1173 (May 25, 2012)

Cell 149: 1164-1173 Contingency and statistical laws in replicate microbial closed ecosystems Doeke R. Hekstra and Stanislas Leibler  

Cell 149: 1152-1163 (May 25, 2012)

Cell 149: 1152-1163 Identification of the Cortical Neurons that Mediate Antidepressant Responses Eric F. Schmidt, Jennifer L. Warner-Schmidt, Benjamin G. Otopalik, Sarah B. Pickett, Paul Greengard and Nathaniel Heintz

Rockefeller scientists pioneer new method to determine mechanisms of drug action

Knowing that a drug works is great. Knowing how it works is a luxury. And until now, determining a drug’s mechanism of action has been a tedious and difficult process for scientists. Researchers led by Tarun Kapoor at The Rockefeller University, in collaboration with Olivier Elemento at Weill Cor...

Two Rockefeller postdocs win Blavatnik Awards

Two Rockefeller University postdoctoral fellows have been named winners in the 2012 Blavatnik Awards for Young Scientists competition from The New York Academy of Sciences. Andrey Feklistov, from Seth Darst’s Laboratory of Molecular Biophysics, and Nicholas Stavropoulos, from Michael Young’s Lab...

Journal of Experimental Medicine online: May 21, 2012

Journal of Experimental Medicine online: May 21, 2012 Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage Matthew M. Meredith, Kang Liu, Guillaume Darrasse-Jeze, Alice O. Kamphorst, Heidi A. Schreiber, Pierre Guermonprez, Juliana Ido...

In the News

Out for Blood   “‘They’re hunters,’ says Leslie Vosshall, the Robin Chemers Neustein Professor at the Rockefeller University of New York, an expert on the science of smell and someone who is not afraid to put her arm into a chamber of mosquitoes and get bitten a lot. ‘And they’ve adapt...

Rockefeller hosts first Leon Levy Neuroscience Fellows Symposium

The first Leon Levy Neuroscience Fellows Symposium will be held at Rockefeller University on Wednesday, May 16. Levy Fellows from Rockefeller, Columbia and New York universities, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College will discuss their latest neuroscience resear...

Vanessa Ruta honored with McKnight Scholar Award

Vanessa Ruta, assistant professor at The Rockefeller University and head of the Laboratory of Neurophysiology and Behavior, has been honored with a McKnight Scholar Award for her research on the functional organization of the neural circuits underlying olfactory learning. The 2012 awards, present...

The EMBO Journal online: May 15, 2012

The EMBO Journal online: May 15, 2012 A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis Ruth Simon, Heike Brylka, Herbert Schwegler, Sathish Venkataramanappa, Jacqueline Andratschke, Christoph Wiegreffe, Pentao Liu, Elaine Fuchs, Nancy A Jenkins, Neal G Copeland, Carmen Birchmeier and S...

Developmental Cell 22: 913-926 (May 15, 2012)

Developmental Cell 22: 913-926 Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David A. Elliott, Mark Solloway, Elisa Len...

In the News

The Veins of a Leaf: Revealing Nature's Mathematical System  "Nature is a great architect, and the vascular network - or veins - of a leaf are key to its structure. Mathematical physicists [Marcelo Magnasco and Eleni Katifori] at Rockefeller University  use fluorescent dye and time lapse photogra...

Journal of Experimental Medicine 209: 1011-1028 (May 7, 2012)

Journal of Experimental Medicine 209: 1011-1028 Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice Fabienne Billiard, Camille Lobry, Guillaume Darrasse-Jèze, Janelle Waite, Xia Liu, Hugo Mouquet, Amanda DaNave, Michelle Tait, Juliana Idoyaga, Marylène Leb...

Science 336: 593-597 (May 4, 2012)

Science 336: 593-597 Removal of shelterin reveals the telomere end-protection problem Agnel Sfeir and Titia de Lange

Science 336: 604-608 (May 4, 2012)

Science 336: 604-608 Radio-wave heating of iron oxide nanoparticles can regulate plasma glucose in mice Sarah A. Stanley, Jennifer E. Gagner, Shadi Damanpour, Mitsukuni Yoshida, Jonathan S. Dordick and Jeffrey M. Friedman

American Philosophical Society elects Cori Bargmann to membership

Cori Bargmann, Torsten N. Wiesel Professor at The Rockefeller University and an investigator at the Howard Hughes Medical Institute, has been elected to the American Philosophical Society in the biological sciences. The American Philosophical Society is an honorary society that elects new members...

In the News

Remote-controlled genes trigger insulin production   "The work, in which a team used radio waves to switch on engineered insulin-producing genes in mice, is published today in Science. Jeffrey Friedman, a molecular geneticist at the Rockefeller University in New York and lead author of the study,...

Influenza “histone mimic” suppresses antiviral response

For a virus like influenza, the key to success isn’t in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at The Rockefeller University has identified a novel mechanism by which influenza viruses hijack key regulators of the human body’s normal antivi...

Rockefeller creates Cohn-Steinman Professorship to honor discoverers of dendritic cells

The Rockefeller University is creating the Cohn-Steinman Professorship to honor two of its most accomplished scientists, Nobel Prize winner Ralph Steinman and his mentor Zanvil A. Cohn, both of whom made seminal scientific discoveries that transformed the field of immunology. Steinman passed away...

In the News

Gift to Support Lab Collaboration   "A pair of Rockefeller University scientists will forever be honored with a new professorship, designed to pay tribute to the spirit of collaboration and mentoring. It was 1970 when Ralph M. Steinman came to Rockefeller University to be a postdoc in the lab of ...

Nature online: April 4, 2012

Nature online: April 4, 2012 An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration Ting Chen, Evan Heller, Slobodan Beronja, Naoki Oshimori, Nicole Stokes and Elaine Fuchs

Proceedings of the National Academy of Sciences USA 109: 6205-6210 (April 17, 2012)

Proceedings of the National Academy of Sciences USA 109: 6205-6210 Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus Erick Giang, Marcus Dorner, Jannick C. Prentoe, Marlène Dreux, Matthew J. Evans, Jens Bukh, Charles M. Rice, Alexander Ploss, Dennis R...

Proceedings of the National Academy of Sciences USA 109: 6181-6186 (April 17, 2012)

Proceedings of the National Academy of Sciences USA 109: 6181-6186 Mouse model recapitulating human Fcγ receptor structural and functional diversity Patrick Smith, David J. DiLillo, Stylianos Bournazos,Fubin Li and Jeffrey V. Ravetch

Proceedings of the National Academy of Sciences USA 109: 6072-6077 (April 17, 2012)

Proceedings of the National Academy of Sciences USA 109: 6072-6077 RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates Anupam K. Chakravartya, Roman Subbotin, Brian T. Chait and Stewart Shuman

Proceedings of the National Academy of Sciences USA 109: 6175-6180 (April 17, 2012)

Proceedings of the National Academy of Sciences USA 109: 6175-6180 Viral-induced encephalitis initiates distinct and functional CD103+ CD11b+ brain dendritic cell populations within the olfactory bulb Paul M. D'Agostinoa, Changsoo Kwaka, Haley A. Vecchiarellia, Judit Gal Totha, James M. Millera, ...

Proceedings of the National Academy of Sciences USA 109: 5779-5784 (April 10, 2012)

Proceedings of the National Academy of Sciences USA 109: 5779-5784 Mutagenesis of pairwise combinations of histone amino-terminal tails reveals functional redundancy in budding yeast Jung-Ae Kima, Jer-Yuan Hsub, M. Mitchell Smithb and C. David Allis

Cori Bargmann honored with Dart/NYU Biotechnology Achievement Award

Cori Bargmann, head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior at Rockefeller University, will receive the twelfth annual Dart/NYU Biotechnology Achievement Award in Basic Biotechnology. Bargmann, the Torsten N. Wiesel Professor at Rockefeller and an investigator at H...

Genes & Development 26: 693-704 (April 1, 2012)

Genes & Development 26: 693-704 Quantitative functions of Argonaute proteins in mammalian development Dongmei Wang, Zhaojie Zhang, Evan O'Loughlin, Thomas Lee, Stephane Houel, Dónal O'Carroll, Alexander Tarakhovsky, Natalie G. Ahn and Rui Yi

Science 335: 1617-1621 (March 30, 2012)

Science 335: 1617–1621 Control of sleep by cyclin A and its regulator Dragana Rogulja and Michael W. Young We show that cyclin A (CycA) and regulator of cyclin A1, essential cell cycle factors, function in postmitotic neurons to promote sleep in Drosophila melanogaster. Reducing the abundance of ...

New England Journal of Medicine 366: 1181-9 (March 29, 2012)

New England Journal of Medicine 366: 1181–1189 Brodalumab, an anti–interleukin-17–receptor antibody for psoriasis Kim A. Papp, Craig Leonardi, Alan Menter, Jean-Paul Ortonne, James G. Krueger, Gregory Kricorian, Girish Aras, Juan Li, Chris B. Russell, Elizabeth H.Z. Thompson, and Scott Baumgar...

In the News

Winners unlock big questions on cells   "Dr. James E. Darnell Jr. and Robert G. Roeder, Ph.D., both of whom work at Rockefeller University in New York City, will receive the [Albany Medical Center] prize during a May 11 ceremony in Albany. The $500,000 prize is the largest award in medicine and s...

Albany Medical Center Prize awarded to James E. Darnell Jr. and Robert G. Roeder

Two Rockefeller University pioneers in the field of gene regulation and expression will be honored with the Albany Medical Center Prize in Medicine and Biomedical Research, the nation’s largest prize in medicine. James E. Darnell Jr., head of the Laboratory of Molecular Cell Biology at Rockefelle...

In the News

Pair will receive $250G for outstanding research   "A former student and teacher duo at the Massachusetts Institute of Technology will receive $250,000 from the March of Dimes next month for creating advances in treating skin cancers, severe burns and other skin diseases...[Elaine] Fuchs began wo...

Jeffrey V. Ravetch and Michael W. Young to receive Canada Gairdner International Awards

Two Rockefeller University scientists will be honored with a Canada Gairdner International Award this year, which are given for significant discoveries in medical science. Jeffrey V. Ravetch, Theresa and Eugene Lang Professor and head of the Leonard Wagner Laboratory of Molecular Genetics and Imm...

Marc Tessier-Lavigne to receive Friesen International Prize

Marc Tessier-Lavigne will receive the Henry G. Friesen International Prize in Health Research. The Prize, established by the Friends of Canadian Institutes of Health Research in collaboration with the Canadian Academy of Health Sciences, recognizes exceptional innovation by a visionary health lea...

Nature online: March 18, 2012

Nature online: March 18, 2012 Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein Ari J. Firestone, Joshua S. Weinger, Maria Maldonado, Kari Barlan, Lance D. Langston, Michael O’Donnell, Vladimir I. Gelfand, Tarun M. Kapoor and James K. Chen We describe the discovery of ciliobre...

Announcements

Bring your child to work. In celebration of national “Take Your Child to Work Day,” Human Resources is hosting activities from 9 a.m. to 3 p.m. on Thursday, April 26. Children between the ages of 8 and 12 who are accompanied by an adult are welcome. The registration deadline is Friday, April 13...

New strategic plan to emphasize recruitment, hospital, infrastructure

After a series of weekly meetings held throughout the fall and winter, the university’s strategic planning committee, chaired by President Marc Tessier-Lavigne, has identified several themes that will likely become central elements of the plan’s first draft. The final plan is to be presented to ...

$15 million gift from Helmsley Trust to fund research on digestive diseases

by ZACH VEILLEUX A new $15 million gift — among the largest donation to the university since the closure of the Campaign for Collaborative Science last June — will help fund research into digestive disorders, including metabolic diseases, cancers and infections. The gift is the university’...

CFC playgrounds to be renovated

by ZACH VEILLEUX Three outdoor playgrounds used by the Child and Family Center’s 122 children are slated to be updated and slightly expanded over the coming months. The infant and toddler playground located on the west side of Sophie Fricke Hall, used by children up to three years old, was i...

Norton Zinder, pioneering molecular geneticist, dies at 83

Norton D. Zinder, a geneticist and microbiologist whose research on the genetics of bacteria and on the properties of bacteriophages — viruses that infect bacteria — provided seminal information on the mechanisms of heredity, died February 3 after a long illness. He was 83. Dr. Zinder was...

Board elects Dinakar Singh, Susan Lyne

by JOSEPH BONNER The university’s Board elected two new trustees at its fall meeting on November 16: Dinakar Singh and Susan Lyne. The board now numbers 42.       Mr. Singh is the founding partner of TPG-Axon Capital, a global investment firm. Through offices in New York, London, Hong Kong...

Dennis Ryan

Dennis Ryan, 63, a security guard who worked mostly day and evening shifts, died January 29. Born and raised in Hell’s Kitchen, Mr. Ryan had a career in the NYPD, from which he retired as a detective in 1986. He had been with Rockefeller since 2006. “He had an outgoing personality and loved to s...

Milestones

Awarded: Elaine Fuchs, the 2012 March of Dimes Prize in Developmental Biology. The prize, which Dr. Fuchs shares with Howard Green of Harvard Medical School, was established in 1996 as a tribute to the pioneering virologist Jonas Salk, and recognizes leaders in the field of developmental biology ...

Titia de Lange to receive Heineken Prize

Titia de Lange, Leon Hess Professor and head of the Laboratory of Cell Biology and Genetics at Rockefeller University, has been awarded the Dr H.P. Heineken Prize for Biochemistry and Biophysics, the first time the award has been given to a woman. Presented by the Royal Netherlands Academy for Ar...

Nature 483: 428-33 (March 14, 2012)

Nature 483: 428–433 Suppression of the antiviral response by an influenza histone mimic Ivan Marazzi, Jessica S. Y. Ho, Jaehoon Kim, Balaji Manicassamy, Scott Dewell, Randy A. Albrecht, Chris W. Seibert, Uwe Schaefer, Kate L. Jeffrey, Rab K. Prinjha, Kevin Lee, Adolfo García-Sastre, Robert G. Roe...