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New structure shows how cells assemble protein-making machinery

Scientists at The Rockefeller University have created the most detailed three-dimensional images to date of an important step in the process by which cells make the nano-machines responsible for producing all-important protein. The results, described December 15 in Science, are prompting the rese...

Rockefeller’s annual Celebrating Science benefit raises $2.8 million, an all-time record

by Alexandra MacWade, assistant editor Last month, 400 guests gathered on campus for cocktails, a lecture on next-generation genomics given by Robert B. Darnell, and a festive dinner. The event—Rockefeller’s fifth annual Celebrating Science benefit—raised a record $2.8 million for the uni...

Molecular biologist Bonnie Bassler receives Rockefeller’s Pearl Meister Greengard Prize

by Alexandra MacWade, assistant editor For hundreds of years, bacteria were thought of as reclusive, antisocial organisms. But molecular biologist Bonnie Bassler, known to some as the “Bacteria Whisperer,” discovered that these single-celled creatures actually talk to one another and c...

Fifty years after landmark methadone discovery, stigmas and misunderstandings persist

Methadone, the first pharmacological treatment for heroin addiction, was pioneered 50 years ago by Rockefeller University’s Mary Jeanne Kreek and her colleagues. Since then the drug, which is widely used in treatment programs across the globe, has saved countless lives and allowed millions of her...

First structural map of the cystic fibrosis protein sheds light on how mutations cause disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. This achievement, described December 1 in Cell, offers the kinds of insights essential to better understanding and treating this oft...

Elaine Fuchs to receive 2016 Vanderbilt Prize in Biomedical Science

Elaine Fuchs, Rebecca C. Lancefield Professor and head of the Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, has won the 2016 Vanderbilt Prize in Biomedical Science for her innovative use of reverse genetics to understand skin diseases and cancer stem cells. The priz...

Survey of New York City soil uncovers medicine-making microbes

Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet. Researchers at The Rockefeller University have shown that the dirt beneath New York City teems with our tiny allies in the fight against disease. In soil c...

Neuroscientist Huda Y. Zoghbi is elected to the Board

by Alexandra MacWade, assistant editor Huda Y. Zoghbi, a pediatric neurologist and neuroscientist who has made key discoveries in the study of brain disorders, has been elected to Rockefeller’s Board of Trustees. With her election, which took place at the Board’s October 19 meeting, the univ...

Rockefeller’s Science Outreach program explores the microbes in food

If you’ve ever forgotten about a cheese wedge in the fridge, you may have discovered something mysterious growing on it, a sure sign that it’s no longer edible. But have you ever wondered where the microbes responsible for that change came from? That’s one of several questions that the late...

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has won the 2016 Inserm Grand Prix for his work on the genetic basis of infectious diseases. The prestigious award, given annually by Inserm—the French National Institute of Health and ...

New research clarifies why wounds heal more slowly with age

Older bodies need longer to mend. This reality of aging has been documented since World War I, with the observation that wounds heal slower in older soldiers. Yet until now, researchers have not been able to tease out what age-related changes hinder the body’s ability to repair itself. Recent e...

Gaby Maimon, who studies sophisticated brain functions in fruit flies, is promoted to associate professor

Neuroscientist Gaby Maimon, who heads the Laboratory of Integrative Brain Function, will become an associate professor as of January 1, 2017. His research program explores how the brain performs calculations to estimate values like angles and time, and is based on the idea that fruit flies, his r...

Awards, Arrivals, and Promotions

Congratulations to our latest award winners: Winrich Freiwald has won the 2016 W. Alden Spencer Award. The prize, given by Columbia University, recognizes outstanding contributions in neuroscience. Dr. Freiwald, who shares the prize with his long-time collaborator Doris Y. Tsao of Caltech, presen...

Researchers discover new antibiotics by sifting through the human microbiome

Most antibiotics in use today are based on natural molecules produced by bacteria—and given the rise of antibiotic resistance, there’s an urgent need to find more of them. Yet coaxing bacteria to produce new antibiotics is a tricky proposition. Most bacteria won’t grow in the lab. And even whe...

Researchers shed new light on RNA’s journey out of a cell’s nucleus

Cells secure DNA within their nuclei like a secret code stashed in a vault. However, the tightly controlled borders of the nucleus create a challenge: In order for the cell to produce essential proteins, messages derived from DNA must somehow escape the nucleus in the form of RNA molecules. New w...

Scientists prove how genetics change behavior by studying worms’ foraging strategies

“Organisms pay attention to what other members of their species are doing,” says Cori Bargmann, a neuroscientist at Rockefeller University. “It’s a very robust phenomenon that you see from humans on Twitter to bacteria, and everything in between.” That’s why Bargmann, Torsten N. W...

Researchers watch in 3D as neurons talk to each other in a living mouse brain

No single neuron produces a thought or a behavior; anything the brain accomplishes is a vast collaborative effort between cells. When at work, neurons talk rapidly to one another, forming networks as they communicate. Researchers led by Rockefeller University’s Alipasha Vaziri are developing tech...

Pioneering drug discovery company Bridge Medicines launched to advance promising early technologies in major academic institutions through human proof of concept

The Tri-Institutional Therapeutics Discovery Institute, a partnership between Memorial Sloan Kettering Cancer Center, The Rockefeller University, Weill Cornell Medicine and Takeda, joins with Deerfield Management and Bay City Capital to create an accelerated path to innovative therapies to treat ...

Winrich Freiwald wins Columbia University’s 2016 W. Alden Spencer Award

Winrich Freiwald, associate professor and head of the Laboratory of Neural Systems, has received the 2016 W. Alden Spencer Award. The prize, given by Columbia University, recognizes outstanding research contributions in the field of neuroscience. Freiwald shares the award with his long-time colla...

Child and Family Center expansion to 15 classrooms is complete

  The Rockefeller University Child and Family Center has grown. The recently completed expansion project, which included the construction of five new classrooms on the second floor of the Graduate Students Residence, has doubled the number of infant spots available in the child care program and a...

Genomic testing could speed research on skin disease and bring new drugs to patients faster

In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them. Unfortunately, in the real world, it can take several months to determine whether a given patient will respond to one of these medications, which target specif...

Study uncovers how cells organize the growth of their structural filaments

To take shape, to move and to reproduce, cells need internal scaffolding composed of slender filaments known as microtubules. Before the cell can use microtubules for these and other essential functions, it must first organize them into carefully crafted bundles, which become the basis for three ...

A possible explanation for why male mice tolerate stress better than females

The nerves we feel before a stressful event—like speaking in public, for example—are normally kept in check by a complex system of circuits in our brain. Now, scientists at Rockefeller University have identified a key molecule within this circuitry that is responsible for relieving anxiety. Intr...

Thinking like a scientist: Research assistants at Rockefeller

by Alexandra MacWade, assistant editor As an undergraduate, Raquel Hernandez-Solis knew she wanted to pursue a graduate degree in the biosciences. She assumed she would follow the trajectory of many of her peers: apply to schools in her senior year and begin a Ph.D. program right upon graduation...

Sebastian Klinge receives 2016 NIH New Innovator Award

Sebastian Klinge, assistant professor and head of the Laboratory of Protein and Nucleic Acid Chemistry, has won a National Institutes of Health Director’s New Innovator Award. The prestigious award, which is given as a five-year grant of up to $1.5 million, supports early-career investigators who...

Rockefeller graduate Monica Mugnier wins 2016 NIH Early Independence Award

Monica Mugnier, who completed her Ph.D. at Rockefeller earlier this year, is one of 16 junior investigators nationwide to receive a National Institutes of Health Director’s Early Independence Award. The award, which is part of the NIH’s High-Risk, High-Reward Research program, allows early-caree...

Study explains how an intestinal microbe protects against other, more dangerous bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside. Probiotics consisting of beneficial microorganisms, meanwhile, have the potential to delive...

Rockefeller University awarded $27 million NIH grant to fund clinical and translational science

Rockefeller University’s Center for Clinical and Translational Science, established a decade ago to accelerate the pace of translating scientific discoveries into interventions shown to improve health, has received $27 million from the National Institutes of Health to fund ongoing and expanded wo...

Bonnie Bassler to receive the 2016 Pearl Meister Greengard Prize

NEW YORK, NY—The Rockefeller University has announced that molecular biologist Bonnie Bassler of Princeton University and the Howard Hughes Medical Institute will receive the 2016 Pearl Meister Greengard Prize, an annual award celebrating the achievements of extraordinary women scientists. She wi...

Rockefeller boosts its wellness offerings

by Alexandra MacWade, assistant editor "Your head is down and you’re gritting your teeth and you’re pedaling hard,” says Timothy Blanchfield, describing what it’s like to be in one of the spin classes he teaches at Rockefeller’s fitness center. Mr. Blanchfield, a triathlete who has bee...