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Awards and Honors

David Allis, pioneer in epigenetics, to receive prestigious Japan Prize

C. David Allis, a pioneer in the field of epigenetics whose discovery that chemical modifications of DNA-packaging proteins play a key role in regulating the activity of individual genes, will be awarded the 2014 Japan Prize in Life Sciences. The announcement, by the Japan Prize Foundation, was m...

In the News

Rockefeller University’s C. David Allis Wins Japan Prize   “Our major challenge, hopefully one taken up by the next generation of young scientists who are intrigued with epigenetics, will be to learn how to better harness the potential of the epigenetic mechanisms to bring about better health ...

Nature Cell Biology online: January 26, 2014

Nature Cell Biology online: January 26, 2014 In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Wen-Hui Lien, Lisa Polak, Mingyan Lin, Kenneth Lay, Deyou Zheng and Elaine Fuchs
Science News

New RNA interference technique finds seven genes for head and neck cancer

In the hunt for genetic mutations that cause cancer, there is a lot of white noise. So although genetic sequencing has identified hundreds of genetic alterations linked to tumors, it’s still an enormous challenge to figure out which ones are actually responsible for the growth and metastasis of c...

In the News

Rockefeller University's Quest to Cure Everything   "While everyone’s eager for cures and discoveries, RU’s scientists openly share that generous donor-funding encourages them to be productive and take risks, but thankfully relieves them of the fear of losing funding—which research scientist...

Rockefeller University establishes $25 million fund for drug discovery

A new $25 million fund to help develop basic research discoveries into new medical therapies will provide support for dozens of promising Rockefeller projects over a five-year period, the university announced today. The fund, which will enable the university to award grants ranging from $10,000 t...
Awards and Honors

Neuroscientist Gaby Maimon given top honor from White House for early career scientists

Gaby Maimon, assistant professor and head of the Laboratory of Integrative Brain Function at Rockefeller, has been chosen by President Obama as one of 20 NIH scientists to receive the Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the U.S. government t...

Science online: January 17, 2014

Science online: January 17, 2014 Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas Daniel Schramek, Ataman Sendoel, Jeremy P. Segal, Slobodan Beronja, Evan Heller, Daniel Oristian, Boris Reva and Elaine Fuchs

Nature Medicine online: January 12, 2014

Nature Medicine online: January 12, 2014 Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo David J. DiLillo, Gene S. Tan, Peter Palese and Jeffrey V. Ravetch

Statement by Rockefeller University President Marc Tessier-Lavigne opposing academic boycotts

Three U.S. scholarly associations have announced their intention to support a proposed boycott of academic institutions in Israel. Such academic boycotts contradict a core principle of academic freedom by restricting free and open communication within the academic community. The key principles ha...

Nature Medicine online: December 22, 2013

Nature Medicine online: December 22, 2013 Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection Peter Liehl, Vanessa Zuzarte-Luís, Jennie Chan, Thomas Zillinger, Fernanda Baptista, Daniel Carapau, Madlen Konert, Kirsten K. Hanson, Céline Carret, Caroline Lassnig,...

Molecular Psychiatry online: December 17, 2013

Molecular Psychiatry online: December 17, 2013 Hippocampal gene expression changes underlying stress sensitization and recovery J.D. Gray, T.G. Rubin, R.G. Hunter and B.S. McEwen

Proceedings of the National Academy of Sciences USA 110: 20455-20460 (12-17-13)

Proceedings of the National Academy of Sciences USA 110: 20455-20460 Flavin reduction activates Drosophila cryptochrome Anand T. Vaidya, Deniz Top, Craig C. Manahan, Joshua M. Tokuda, Sheng Zhang, Lois Pollack, Michael W. Young and Brian R. Crane

Molecular Cell 52: 734-45 (12-12-13)

Molecular Cell 52: 734-45 Autoinhibition and polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase haspin to mitosis Cristina Ghenoiu, Michael S. Wheelock and Hironori Funabiki

Science 342: 1254-1258 (12-6-13)

Science 342: 1254-1258 MicroRNA-128 governs neuronal excitability and motor behavior in mice Chan Lek Tan, Joshua L. Plotkin, Morten T. Venø, Melanie von Schimmelmann, Philip Feinberg, Silas Mann, Annie Handler, Jørgen Kjems, D. James Surmeier, Dónal O’Carroll, Paul Greengard and Anne Schaefer

In the News

Pearl Meister Greengard prize winner followed a gut feeling for 16 years   "Pediatric neurologist and neuroscientist Huda Y. Zoghbi won Rockefeller University's 10th annual Pearl Meister Greengard Prize, which on Thursday night she attributed in part to following 'a gut feeling.' For 16 years, sh...
Science News

Large-scale survey of clinical research participants shows mostly positive experiences

A multi-center survey of close to 5,000 volunteers who enrolled in clinical research studies, the first of its kind, shows that by and large participants feel valued and respected by investigators. But although many gave high marks to the research teams’ trustworthiness and ability to explain the...
Campus News

Michael A. Foley named director of Tri-I Therapeutics Discovery Institute

Michael A. Foley, an accomplished chemist and entrepreneur with more than 25 years of industry and academic experience, has been named director of the new Tri-Institutional Therapeutics Discovery Institute, a pioneering collaboration of Weill Cornell Medical College, The Rockefeller University an...

In the News

Biology's coefficient: Joel Cohen uses the tools of mathematics to deconstruct questions of life   "That study of Earth’s human population is only a drop in the bucket of the diverse, seemingly disparate, subjects that Cohen has addressed in his five-decade-long career. His studies of food webs,...

Genes and Development online: November 27, 2013

Genes and Development online: November 27, 2013 Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation Junwei Shi, Warren A. Whyte, Cinthya J. Zepeda-Mendoza, Joseph P. Milazzo, Chen Shen, Jae-Seok Roe, Jessica L. Minder, Fatih Mercan, Eric Wang, Melanie A. Eckersley-M...

Nature online: November 27, 2013

Nature online: November 27, 2013 Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity John W. Schoggins, Donna A. MacDuff, Naoko Imanaka, Maria D. Gainey, Bimmi Shrestha, Jennifer L. Eitson, Katrina B. Mar, R. Blake Richardson, Alexander V. Ratushny, Vladimir L...

Proceedings of the National Academy of Sciences USA online: November 26, 2013

Proceedings of the National Academy of Sciences USA online: November 26, 2013 Nfatc1 orchestrates aging in hair follicle stem cells Brice E. Keyes, Jeremy P. Segal, Evan Heller, Wen-Hui Lien, Chiung-Ying Chang, Xingyi Guo, Dan S. Oristian, Deyou Zheng and Elaine Fuchs

Proceedings of the National Academy of Sciences USA 110: 19501-19506 (11-26-13)

Proceedings of the National Academy of Sciences USA 110: 19501-19506 Antitumor activities of agonistic anti-TNFR antibodies require differential FcγRIIB coengagement in vivo Fubin Li and Jeffrey V. Ravetch

Journal of Experimental Medicine online: November 25, 2013

Journal of Experimental Medicine online: November 25, 2013 Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission Marine Malbec, Françoise Porrot, Rejane Rua, Joshua Horwitz, Florian Klein, Ari Halper-Stromberg, Johannes F. Scheid, Caroline Eden, Hugo Mouquet, Michel C. Nuss...

Nature Structural Molecular Biology online: November 24, 2013

Nature Structural Molecular Biology online: November 24, 2013 The human cap-binding complex is functionally connected to the nuclear RNA exosome Peter Refsing Andersen, Michal Domanski, Maiken S. Kristiansen, Helena Storvall, Evgenia Ntini, Celine Verheggen, Aleks Schein, Jakob Bunkenborg, Ina Po...

Nature Neuroscience online: November 24, 2013

Nature Neuroscience online: November 24, 2013 Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway Jessica J. Walsh, Allyson K. Friedman, Haosheng Sun, Elizabeth A. Heller, Stacy M. Ku, Barbara Juarez, Veronica L. Burnham, Michelle S. Mazei-Robison, Deveroux Ferguson, Sa...

Cell 155: 1034-1048 (11-21-13)

Cell 155: 1034-1048 Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition Martin S. Taylor, John LaCava, Paolo Mita, Kelly R. Molloy, Cheng Ran Lisa Huang, Donghui Li, Emily M. Adney, Hua Jiang, Kathleen H. Burns, Brian T. Chait, Michael P. Rout...

Journal of Experimental Medicine 210: 2739-2753 (11-18-13)

Journal of Experimental Medicine 210: 2739-2753 Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells Elissa K. Deenick, Danielle T. Avery, Anna Chan, Lucinda J. Berglund, Megan L.  Ives, Leen Moens, Jennifer L. Stodda...

Proceedings of the National Academy of Sciences USA online: November 11, 2013

Proceedings of the National Academy of Sciences USA online: November 11, 2013 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of σ70 domain 1.1 Brian Bae, Elizabeth Davis, Daniel Brown, Elizabeth A. Campbell, Sivaramesh Wigneshweraraj and Seth A. Darst

Cell 155: 881-893 (11-7-13)

Cell 155: 881-893 Opposing dopaminergic and GABAergic neurons control the duration and persistence of copulation in Drosophila Michael A. Crickmore and Leslie B. Vosshall

Neuron online: November 6, 2013

Neuron online: November 6, 2013 Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin Jing Yang, Robby M. Weimer, Dara Kallop, Olav Olsen, Zhuhao Wu, Nicolas Renier, Kunihiro Uryu and Marc Tessier-Lavigne

In the News

Google, Evernote, Rockefeller U. headline launch Of Forbes’ Innovators event series   "[The] first event, The Future Of The Brain, has a great lineup. You’ll hear from Cori Bargmann, the Breathrough Prize-winning neurobiologist from Rockefeller University, whose work with roundworms has shed n...

Nature online: October 30, 2013

Nature online: October 30, 2013 Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia Masashi Shingai, Yoshiaki Nishimura, Florian Klein, Hugo Mouquet, Olivia K. Donau, Ronald Plishka, Alicia Buckler-White, Michael Seaman, Michael Piatak, Jeffrey D. Lifson...

Nature online: October 30, 2013

Nature online: October 30, 2013 Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia Masashi Shingai, Yoshiaki Nishimura, Florian Klein, Hugo Mouquet, Olivia K. Donau, Ronald Plishka, Alicia Buckler-White, Michael Seaman, Michael Piatak, Jeffrey D. Lifson...

Nature 502: 563-566 (10-24-13)

Nature 502: 563-566 MX2 is an interferon-induced inhibitor of HIV-1 infection Melissa Kane, Shalini S. Yadav, Julia Bitzegeio, Sebla B. Kutluay, Trinity Zang, Sam J.  Wilson, John W. Schoggins, Charles M. Rice, Masahiro Yamashita, Theodora  Hatziioannou and Paul D. Bieniasz

Proceedings of the National Academy of Sciences USA 110: 4108-4117 (10-22-13)

Proceedings of the National Academy of Sciences USA 110: 4108-4117 Network model of top-down influences on local gain and contextual interactions in visual cortex Valentin Piëch, Wu Li, George N. Reeke and Charles D. Gilbert  

Proceedings of the National Academy of Sciences USA online: October 21, 2013

Proceedings of the National Academy of Sciences USA online: October 21, 2013 High-throughput imaging of neuronal activity in Caenorhabditis elegans Johannes Larsch, Donovan Ventimiglia, Cornelia I. Bargmann and Dirk R. Albrecht
Awards and Honors

Neuroscientist Winrich Freiwald awarded New York Stem Cell Foundation grant

Winrich Freiwald, assistant professor and head of the Laboratory of Neural Systems at The Rockefeller University, has been named a Robertson Investigator by the New York Stem Cell Foundation. He is one of seven scientists who will receive $1.5 million over the next five years to expand their labo...

Immunity 39: 676-686 (10-17-13)

Immunity 39: 676-686 An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis Bertrand Boissonsend, Chenhui Wang, Vincent Pedergnana, Ling Wu, Sophie Cypowyj, Michel Rybojad, Aziz Belkadi, Capucine Picard, Laurent Abel, Claire Fieschi, Anne ...

New England Journal of Medicine 369: 1704-1714 (10-31-13)

New England Journal of Medicine 369: 1704-1714 Deep dermatophytosis and inherited CARD9 deficiency Fanny Lanternier, Saad Pathan, Quentin B. Vincent, Luyan Liu, Sophie Cypowyj, Carolina Prando, Mélanie Migaud, Lynda Taibi, Aomar Ammar-Khodja, Omar Boudghene Stambouli, Boumediene Guellil, Frederiq...
Science News

Gene is linked to deadly runaway fungal infection

For most people, a fungal infection like athlete’s foot means a simple trip to the drugstore and a reminder to bring shower shoes to the gym. But in very rare cases, fungal infections can spread below the skin’s surface and onto the lymph nodes, bones, digestive tract or even the brain. Research...
Campus News

Rockefeller scientists among those involved in search for Higgs boson

This week’s announcement that two physicists have received the Nobel Prize in Physics for their discovery of the Higgs boson is also a victory for thousands of scientists, including more than 2,000 from the United States, who worked to collect data and analyze results from particle collisions con...

Cell 155: 345-356 (10-10-13)

Cell 155: 345-356 Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent t-loop formation Ylli Doksani, John Y. Wu, Titia de Lange and Xiaowei Zhuang

Nature Biotechnology online: October 6, 2013

Nature Biotechnology online: October 6, 2013 Strategic addition of an N-linked glycan to a monoclonal antibody improves its HIV-1-neutralizing activity Ruijiang Song, Deena A. Oren, David Franco, Michael S. Seaman and David D. Ho
Awards and Honors

Neurobiologist Vanessa Ruta receives New Innovator Award to fund research on memory wiring in the brain

Vanessa Ruta, head of the Laboratory of Neurophysiology and Behavior, is the latest Rockefeller scientist to be given a prestigious NIH Director’s Award, a collection of awards that recognize highly innovative approaches to contemporary challenges in biomedical research. The New Innovator Award, ...
Campus News

Trio of New York biomedical institutions join forces to accelerate drug development

Memorial Sloan-Kettering Cancer Center, The Rockefeller University and Weill Cornell Medical College announced today that they have formed the pioneering Tri-Institutional Therapeutics Discovery Institute, Inc. (Tri-I TDI) and have partnered with Takeda Pharmaceutical Company, Ltd. This new, grou...

In the News

NYC cockroach study: Bugs vary by neighborhood   "Over the past year, Mark Stoeckle and his team from Rockefeller University did some pretty dirty work, collecting hundreds of dead cockroaches for the National Cockroach Project, a study aimed at analyzing the usually unwelcome creatures."

Cell 155: 107-120 (9-26-13)

Cell 155: 107-120 Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells Laura A. Banaszynski, Duancheng Wen, Scott Dewell, Sarah J. Whitcomb, Mingyan Lin, Nichole Diaz, Simon J. Elsässer, Ariane Chapgier, Aaron D. Goldberg, Eli Canaani, Shahin Rafii...

Developmental Cell online: September 25, 2013

Developmental Cell online: September 25, 2013 Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly John Z. Xue, Eileen M. Woo, Lisa Postow, Brian T. Chait and Hironori Funabiki

Proceedings of the National Academy of Sciences USA online: September 25, 2013

Proceedings of the National Academy of Sciences USA online: September 25, 2013 Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy Yuan Tian, Jerry C. Chang, Emily Y. Fan, Marc Flajolet and Paul Greengard

The EMBO Journal online: September 24, 2013

The EMBO Journal online: September 24, 2013 IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage HyeonJoo Cheon, Elise G. Holvey-Bates, John W. Schoggins, Samuel Forster, Paul Hertzog, Naoko Imanaka, Charles M. Rice, Mark W. Jackson, Damian J. Junk and G...

Proceedings of the National Academy of Sciences USA online: September 23, 2013

Proceedings of the National Academy of Sciences USA online: September 23, 2013 Structure and nucleic acid binding activity of the nucleoporin Nup157 Hyuk-Soo Seo, Bartlomiej J. Blus, Nina Z. Janković and Günter Blobel

Proceedings of the National Academy of Sciences USA online: September 16, 2013

Proceedings of the National Academy of Sciences USA online: September 16, 2013 HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice Joshua A. Horwitz, Ariel Halper-Stromberg, Hugo Mouquet, Alexander D. Gitlin, Anna Tr...

Journal of Experimental Medicine online: September 16, 2013

Journal of Experimental Medicine online: September 16, 2013 Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium Heidi A. Schreiber, Jakob Loschko, Roos A. Karssemeijer, Amelia Escolano, Matthew M. Meredith, Daniel Mucida, Pierre Guermonpr...

Proceedings of the National Academy of Sciences USA online: September 9, 2013

Proceedings of the National Academy of Sciences USA online: September 9, 2013 Decisions on the fly in cellular sensory systems Eric D. Siggia and Massimo Vergassola    
Awards and Honors

Huda Y. Zoghbi, pediatric neurologist, to receive 2013 Pearl Meister Greengard Prize

Huda Y. Zoghbi, M.D., a pediatric neurologist and neuroscientist who has worked on the genetic underpinnings of rare neurological diseases and advanced our understanding of brain disorders, has been selected to receive the tenth annual Pearl Meister Greengard Prize — one of the world’s preemin...

Cell Stem Cell 13: 314-327 (9-5-13)

Cell Stem Cell 13: 314-327 Architectural niche organization by LHX2 is linked to hair follicle stem cell function Alicia R. Folgueras, Xingyi Guo, H. Amalia Pasolli, Nicole Stokes, Lisa Polak, Deyou Zheng and Elaine Fuchs

In the News

A Google Map of Our Brains: The Next Chapter in Neuroscience   "For a lot of the way that different brain regions work together to generate complex functions, we're really stumbling around in the dark," said Dr. Cori Bargmann, a Rockefeller University neuroscientist and co-chair of the project. "...

Nature Structural and Molecular Biology online: September 1, 2013

Nature Structural and Molecular Biology online: September 1, 2013 Regulation of transcription by the MLL2 complex and MLL complex–associated AKAP95 Hao Jiang, Xiangdong Lu, Miho Shimada, Yali Dou, Zhanyun Tang and Robert G. Roeder

Proceedings of the National Academy of Sciences USA online: August 26, 2013

Proceedings of the National Academy of Sciences USA online: August 26, 2013 H3R42me2a is a histone modification with positive transcriptional effects Fabio Casadio, Xiangdong Lu,  Samuel B. Pollock, Gary LeRoy, Benjamin A. Garcia, Tom W. Muir, Robert G. Roeder and C. David  Allis
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