News & HighlightsNews
Researchers discover an epigenetic switch that could be targeted by new cancer therapies
Researchers were able to shut down certain malignancies by disabling a protein complex that regulates cell differentiation.
This tiny cellular portal could open vast possibilities for medicine
Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus. His research could lead to new treatments for cancer and viral diseases.
New tracking tool reveals how T cells adapt in different organs
Researchers uncovered immune dynamics that may inform future therapies for infection, cancer, and autoimmunity.
Scientists map how aging reshapes cells across the entire mammalian body
Age-related changes in cells are synchronized across organs, suggesting common molecular signals that could be targeted with drugs.
A new method reveals hidden rules of gene control
A new cell-free genomics framework isolates the primary impacts of transcription factors and establishes tuberculosis as a model for understanding how genes are regulated.
A protein thought to play a supporting role in DNA replication actually facilitates the whole process
Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight that could inform research into cancer and other diseases.
In rare cases, autoantibodies can cause severe reactions to a live-attenuated virus Chikungunya vaccine that has been discontinued in the U.S.
A new study shows that preexisting autoantibodies in a small subset of the population can allow weakened vaccine viruses to escape control, explaining some adverse events tied to this one kind of Chikungunya vaccine, which is no longer available in the U.S.
Study on brain navigation reveals function of an unconventional electrical-signaling mode in neurons
New work in fruit flies uncovers an electrical trick that allows neurons to compute direction efficiently by juggling multiple signaling mechanisms. These findings could reframe our understanding of how some neurons operate.
The color of your fat could determine the level of your blood pressure
Scientists knew that obesity raises the risk of hypertension. Now Paul Cohen's team has uncovered the mechanism—and the enzyme—that explains how fat can stiffen blood vessels and drive blood pressure upward.
How beige fat keeps blood pressure in check
New study shows that beige fat suppresses an enzyme that promotes high blood pressure, revealing a new molecular pathway and a potential target for future precision therapies.
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