Neuroscientists have long posited that memory functions like an on/off switch—either your brain remembers something or it doesn’t. Priya Rajasethupathy’s team discovered why the truth is more complicated.
New research reveals a cascade of molecular timers unfolding across the hippocampus, thalamus, and cortex determine whether short-term impressions consolidate into long-term memory, with implications for memory-related diseases.
Scientists used light-inducible gene expression to demonstrate that formation of the body axes in human embryo models requires an interplay between chemical cues and mechanical forces.
A newly identified molecular pathway shifts microglia into a protective state, and may lead to Alzheimer's therapies that can reprogram the brain’s own immune defenses.
