Skip to main content
Displaying 1168 of 2850 articles.

Stem cell model offers first glimpse of early human development

The new platform’s ethically grounded approach promises to reveal much about how human embryos form during the earliest stages of pregnancy.

New Mtb study offers a novel paradigm for understanding bacterial transcription

A novel sequencing technique reveals a genetic trick TB may be using to evade the immune system and resist antibiotics.

A pioneering way to target the culprit behind a deadly liver cancer

Researchers have translated a cutting-edge tactic for treating genetic disorders into a fresh approach for potentially stymying cancer.  

Vitamin A may play a central role in stem cell biology and wound repair

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.

New study on mating behaviors offers clues into the evolution of attraction

In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.

Universal tool for tracking cell-to-cell interactions

uLIPSTIC, an updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.

Innovative microscopy tech answers fundamental questions

A powerful tool captures data from an unprecedented 1 million neurons simultaneously, painting a much fuller picture of brain dynamics.

Rogue enzymes cause numerous diseases. A new method could help design drugs to treat them.

A novel platform allows researchers to directly target enzymes implicated in infectious diseases, several genetic disorders, and some cancers for the first time.

Double trouble at chromosome ends

The end replication problem dictates that telomeres shrink unless telomerase intervenes. But the problem is actually twice as complicated, with telomerase providing only part of the solution.

Cutting-edge methods yield surprising insights into Huntington’s disease

New findings add depth to our understanding of neurodegeneration.

Keeping telomerase in check

Telomerase could run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage.

How fruit flies control the brain's "steering wheel"

A newly discovered neural circuit mediates between navigational brain cells, acting as a sort of mental steering wheel. 

Newly discovered genetic malfunction causes rare lung disease

The absence of a single immune cell receptor has been linked to both fewer defenses against mycobacterial infections, such as TB, and damaging buildup of sticky residue in the lungs.  

"Exhausted" immune cells may drive Alzheimer's

A class of ineffective immune cells may be driving Alzheimer’s disease, a finding that could both explain why APOE4 gene increases the risk of the disease and why a new drug can impact it.

Revealing how an ancient genetic invader inhabits our DNA

LINE-1 is associated with disease and aging. The Rout lab has uncloaked the core of its key protein, pointing the way towards therapeutic targets.

A CRISPR pioneer looks back as the first gene-editing therapy is approved

Luciano Marraffini’s research helped lay the groundwork for the newly FDA-approved CRISPR-based therapy for sickle cell anemia. He reflects on how we got here—and where the science is going next.

Innovative method identifies rare brain cell types for the first time

It also reduces the cost of a million single-cell transcriptomes from $10,000 to $700—and the time necessary down to about a day.

A new way of thinking about how organ architecture develops 

By focusing on the emergent features of cell collectives, instead of individual cells, scientists forge a new path for understanding how organs develop their architecture.   

Intriguing science discoveries of 2023

From plumbing the depths of wound repair to tackling how songbirds solve problems, here are some fascinating discoveries that came out of Rockefeller in 2023.

How bacteria recognize viral invasion and activate immune defenses

Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.

How the antioxidant glutathione keeps mitochondria healthy

“I believe this is going to be a very fruitful find. Every time people have studied nutrient sensing, we’ve learned a lot about biology, and many drugs have been developed as a result.”

New blood test could offer earlier detection of common deadly cancers

The low-cost multi-cancer detector can pick up the presence of a telltale protein in a tiny amount of blood in less than two hours.

The bacteria that may trigger multiple sclerosis

New research suggests that the long sought-after environmental trigger for MS is a toxin produced by certain C. perfringens bacteria.

Toward a universal dengue vaccine

Why do our bodies not only fail to learn from prior dengue infection but also become more vulnerable to it as a result? New research pinpoints a subgroup of antibodies that may be to blame.

>

Community-developed guidelines for publishing images help address reproducibility problem in science

The use of images in scientific papers is more popular than ever, but there have been no common standards for their publication—until now.

New method tracks how brain cells age

The novel technique may offer panoramic view into the mechanisms of many diseases and the enigma of aging.

Vocal learning linked to problem solving skills and brain size

The better a songbird is at working its way around obstacles to retrieve a snack, the more complex its vocal learning ability will be.

Unlocking how the new Alzheimer’s drug lecanemab works

As with many cutting-edge therapies, we know more about the drug's effectiveness than we do about how it actually operates. A new study reveals a possible mechanism for its impact on patients.

>

Boosters are key to protecting pregnant individuals and newborns against the worst effects of COVID

Patients with a specific cocktail of COVID exposure had the highest level of antibodies against SARS-CoV-2 and its variants, which also provided a strong immunological shield for their babies.

Researchers find an epigenetic key that unlocks common deadly cancers

In skin, some aberrant adult epidermal stem cells turn on SOX9, kickstarting a process that ultimately activates cancer genes.
View
View