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Displaying 159 of 2841 articles.
February 6, 2024
Newly discovered genetic malfunction causes rare lung disease
The absence of a single immune cell receptor has been linked to both fewer defenses against mycobacterial infections, such as TB, and damaging buildup of sticky residue in the lungs.
December 14, 2023
A CRISPR pioneer looks back as the first gene-editing therapy is approved
Luciano Marraffini’s research helped lay the groundwork for the newly FDA-approved CRISPR-based therapy for sickle cell anemia. He reflects on how we got here—and where the science is going next.
November 13, 2023
How bacteria recognize viral invasion and activate immune defenses
Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
October 30, 2023
The bacteria that may trigger multiple sclerosis
New research suggests that the long sought-after environmental trigger for MS is a toxin produced by certain C. perfringens bacteria.
July 18, 2023
An immune flaw may cause West Nile virus’s deadliest symptoms
With 40% of encephalitis cases now explained by an autoimmune deficiency, West Nile virus "is by far the best understood human infectious disease in the world. It’s stunning.”
April 13, 2023
New tool to study hepatitis B could open the door to a cure
Just as the Rice lab’s work on HCV exposed that virus’s weaknesses, the hope is that this novel approach could do the same for HBV.
February 9, 2023
Homing in on the genetics of severe COVID in children
A trio of faulty genes fail to put the brakes on the immune system’s all-out assault on SARS-CoV-2, leading to the inflammatory overload characteristic of MIS-C.
July 14, 2022
Colorectal cancer tumors both helped and hindered by T cells
Researchers have long disagreed over whether 𝛄𝛅T cells in the gut promote or discourage tumor growth, but new evidence suggests they have the capacity to do both.
June 23, 2022
A third vaccine dose may increase protection from Omicron
The booster appears to galvanize memory B cells into producing potent and versatile antibodies that neutralize both the original virus and its many variants.
May 30, 2022
Hundreds of new drug targets to combat tuberculosis
The study highlights genes that, when silenced, render
vulnerable to antibiotics, and identifies existing drugs that may be effective against one prominent strain.
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