Their newest technique has already uncovered hundreds of hidden bacterial genomes and two promising antibiotics. Now, the same approach could unlock an entire microbial universe—reshaping drug discovery and our understanding of how bacteria shape our environment.
Newly identified compounds appear effective against drug-resistant bacteria. The technique used to reveal them could uncover many more antibiotics, as well as help illuminate a previously hidden microbial world.
Newly discovered weapons of bacterial self-defense take different approaches to achieving the same goal: preventing a virus from spreading through the bacterial population.
Results presented at Conference on Retroviruses and Opportunistic Infections show that two broadly neutralizing antibodies can keep HIV suppressed for months.
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations.
New study demonstrates how high-affinity B cells "bank" their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.
