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Displaying 139 of 2957 articles.
In brief: Mapping the errors that disrupt heartbeat
By determining the structure of a protein linked to a deadly form of arrhythmia, scientists have gained new insights about the condition.
In brief: A closer look at why some drugs cause arrhythmia
Scientists have identified the features that render a potassium channel in the heart vulnerable to interference by a range of drugs.
C. David Allis wins 2017 March of Dimes Prize in Developmental Biology
Allis has received the March of Dimes Prize in Developmental Biology. The award, given to investigators whose research offers hope for the prevention and treatment of birth defects and other infant diseases, honors Allis for his groundbreaking work on gene regulation.
Discovery of a Zika antibody offers hope for a vaccine
Searching for a way to thwart Zika, scientists have discovered an antibody with a potent ability to neutralize the virus.
Shooting the messenger: how one protein allows germ cells to develop
Researchers have identified a molecule that guides the formation of eggs and sperm by preventing a host of factors related to cell death and inflammation from killing the precursors to these cells. Their findings reveal new knowledge about how a mutation in this molecule leads to male sterility.
New study resolves the structure of the human protein that causes cystic fibrosis
In order to better understand how genetic mutations give rise to cystic fibrosis, researchers need to map the protein responsible for the disorder. The new structure has led to new insights on how this molecular channel functions.
A new way to reset gene expression in cancer cells shows promise for leukemia treatment
New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by d...
New structural studies reveal workings of a molecular pump that ejects cancer drugs
Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining i...
Howard C. Hang receives 2017 Eli Lilly Award in Biological Chemistry
Howard C. Hang, Richard E. Salomon Family Associate Professor and head of the Laboratory of Chemical Biology and Microbial Pathogenesis, has won the 2017 Eli Lilly Award in Biological Chemistry. The prize, given by the American Chemical Society, recognizes outstanding research in biological chemi...
Atomic-scale view of bacterial proteins offers path to new tuberculosis drugs
With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, Rockefeller scientists are suggesting strategies for new drugs to curb this growing health problem. Each year, nearly half a million people around the world are infected with m...
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