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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
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Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.
!
Phase III+: The University is open for expanded research operations; only authorized personnel will be admitted on campus. More info here.

Anderson Center Lectures

2021-22 Lecture Series

Dr. Scott Keeney, Ph.D.
Frederick R. Adler Chair Memorial Sloan-Kettering Cancer Center
Thursday, November 4, 12 p.m.
Some assembly required: How to build a meiotic DNA breaking machine
Dr. Ashani Weeraratna, Ph.D.
EV McCollum Professor and Chair of Biochemnistry and Molecular Biology Johns Hopkins Bloomberg School of Health
Thursday, December 2, 12 p.m.
Age against the machine: How aging disrupts the homeostasis of cancer
Dr. Lacramioara Bintu, Ph.D.
Assistant Professor of Bioengineering Brandeis University
Thursday, March 3, 12 p.m.
High-throughput discovery and characterization of human transcriptional repressor and activator domains
Dr. Mike Murphy, Ph.D.
Medical Research Council Mitochondrial Biology Unit and Department of Medicine Cambridge University
Thursday, April 7, 12 p.m.
Mitochondrial metabolites and ROS in health and disease
Dr. Kristy Red-Horse, Ph.D.
Associate Professor of Biology Stanford University
Thursday, May 5, 12 p.m.
Alternative developmental trajectories and their influence on cell behaviors

2020-21 Lecture Series

Dr. Clemens Schmitt, M.D.
Molecular Cancer Research Center, Charité Universitätsmedizin Berlin
Thursday, December 3, 12 p.m.
Turning evil: Tumor-controlling senescence in cancer progres-sion and treatment failure
Dr. Alex Dunn, Ph.D.
Associate Professor, Chemical Engineering Stanford University
February 4, 12 p.m.
Symmetry breaking at cellular adhesion complexes
Dr. Noah Palm, Ph.D.
Assistant Professor of Immunobiology Yale University School of Medicine
Thursday, March 4, 12 p.m.
Mapping Uncharted Landscapes of Host-Microbiota Connectivi-tyactivator domains
Dr. Eric Greene, Ph.D.
Professor, Biochemistry and Molecular Biophysics Columbia University Medical Center
Thursday, April 1, 12 p.m.
Single molecule studies of homologous DNA recombination
Dr. William Kaelin, M.D.
Sidney Farber Professor of Medicine Dana-Farber Cancer Institute and Brigham and Women’s Hospital
Thursday, June 3, 12 p.m.
The von Hippel-Lindau Tumor Suppressor: Insights into Oxygen Sensing, Cancer Metabolism, and Drugging the Undruggable

2019-20 Lecture Series

Dr. Andrea Ablasser, Ph.D.
Associate Professor, Global Health Institute Ecole Polytechnique Fédérale de Lausanne (EPFL)
Thursday, October 3, 12 p.m.
Regulation of innate DNA sens-ing mechanisms
Dr. Xavier Trepat, Ph.D.
ICREA Research Professor Institut de Bioenginyeria de Catalunya (IBEC)
December 5, 12 p.m.
The forces that shape epithelia: from organoids to tumors
Dr. Wendy Bickore, Ph.D.
Director, MRC Genetics Unit University of Edinburgh
Thursday, January 23, 12 p.m.
The 3D genome: gene regula-tion, cell state and disease

2010 to 2019 Lecture Series

Steve Jackson
Wellcome Trust/Cancer Research UK
October 7, 2010
Cellular responses to DNA damage: new molecular insights and new approaches to cancer therapy
Andrew Murray
Harvard University
November 4, 2010
I might like you better if we stuck together: the social biology of sucrose utilization in budding yeast
Hans Clevers
Hubrecht Institute
December 8, 2010
The title of Hans Clevers’ talk will be: Wnt signaling, Lgr5 stem cells and cancer
Johannes Walter
Harvard Medical School
February 3, 2011
The mechanism and cell-cycle regulation of eukaryotic DNA replication
Joachim Lingner
Swiss Institute for Experimental Cancer Research (ISREC)
April 21, 2011
Telomerase and telomeric repeat containing RNA at chromosome ends
Scott Lowe
Cold Spring Harbor Laboratory
September 1, 2011
Constructing and Deconstructing Cancer using Mouse Models and RNAi
Woodring Wright
University of Texas Southwestern Medical Center
October 6, 2011
Telomeres: What replication gymnastics, White Rhinos and telomeric silencing tell us about human aging and disease
Frèdèric J. de Sauvage
Genentech, Inc.
October 24, 2011
Targeting the Hedgehog Pathway in Cancer: From Bench to Clinic
Tanya T. Paull
University of Texas at Austin
November 3, 2011
Integration of DNA repair and oxidative stress signaling through the ATM protein kinase
Philip Beachy
Stanford University, School of Medicine
December 1, 2011
Hedgehog signaling in development, disease, and regeneration
Alan D’Andrea
Dana-Farber Cancer Institute
December 8, 2011
Regulation of DNA Repair by Ubiquitin and SUMO
James Bradner
Harvard Medical School
February 2, 2012
Chemical Inhibition of Bromodomains
Michael B. Yaffe
Massachusetts Institute of Technology
March 1, 2012
A Systems Biology Approach to DNA Damage Signaling: Molecules, Modules, Networks and Patients
David Sabatini
Massachusetts Institute of Technology
April 5, 2012
Growth control through the mTOR pathway
Roel Nusse
Stanford University School of Medicine
May 3, 2012
Wnt signaling and asymmetric divisions of stem cells
Lewis C. Cantley
Weill Medical College of Cornell University
April 4, 2013
PI 3-Kinase and Cancer Metabolism
Scott Armstrong
Memorial Sloan-Kettering Cancer Center
May 2, 2013
Histone Methylation: Mechanisms and Therapeutic Opportunities in Leukemia
Rene Bernards
Netherlands Cancer Institute
October 4, 2013
Finding effective combination therapies for cancer through functional genetics
Lorraine Symington
Columbia University Medical Center
September 5, 2013
Mechanism and regulation of DNA double-strand break processing
Stephen Elledge
Harvard Medical School
February 7, 2014
When half is simply not enough: How aneuploidy drives cancer
David Sabatini
Massachusetts Institute of Technology
March 6, 2014
Regulation of growth by the mTOR pathway
Daniel Durocher
Lunenfeld-Tanenbaum Research Institute, Toronto
April 3, 2014
Writing, reading and regulating histone ubiquitylation during the DNA damage response
Andrei V. Gudkov
Roswell Park Cancer Institute
May 1, 2014
Death by TRAIN: p53 cooperates with interferon to control epigenetic silencing of mammalian “repeatome”
David Shore
University of Geneva
September 29, 2014
A Dynamic Promoter Nucleosome Architecture at Highly Transcribed Genes in Yeast
Frank Pugh
Pennsylvania State University
February 5, 2015
Genomic Mechanisms of Chromatin Organization
Alexander Johnson
University of California San Francisco
June 4, 2015
How Transcription Circuits Evolve and Produce Biological Novelty
Keith Caldecott
University of Sussex
September 3, 2015
DNA Strand Break Repair, Genetic Stability, and Human Neurological Disease
Jeannie Lee
Harvard University
February 4, 2016
To Xist or not?
Martin Hetzer
The Salk Institute
March 3, 2016
Genome organization in the nucleus during development, aging and disease
Evgeny Nudler
New York University School of Medicine
April 7, 2016
New Principles of Transcription- coupled DNA Repair
Jennifer Grandis
University of California San Francisco
December 1, 2016
Head and Neck Cancer Precision Medicine
Rebecca Heald
University of California at Berkeley
April 6, 2017
Mechanisms of mitosis and size control in Xenopus
Nabeel Bardeesy
Harvard Medical School
May 4, 2017
Metabolic heterogeneity in KRAS mutant pancreatic cancer
Agnel Sfeir
New York University School of Medicine
June 1, 2017
Maintaining our genomes: nuclear and mitochondrial
Jared Rutter
University of Utah School of Medicine
September 7, 2017
Mitochondria, Metabolism and Cellular Decisions
Luis Parada
UT Southwestern
October 5, 2017
Glioma Stem Cells: Origin and Molecular Features
Andreas Martin
University of California at Berkeley
December 7, 2017
Substrate processing and mechanochemical coupling of the 26S proteasome – a fine-tuned molecular machine
Alec Kimmelman
NYU Langone Health
February 1, 2018
Identifying Metabolic Dependencies in Pancreatic Cancer
David Cortez
Vanderbilt University
March 1, 2018
Maintaining genome stability: A balancing act at replication forks
Reuben Harris
University of Minnesota
April 5, 2018
Molecular Mechanism and Clinical Impact of APOBEC Mutagenesis in Cancer
Samara Reck-Peterson
University of California San Diego
May 3, 2018
Molecular Mechanisms of Intracellular Transport
Kathryn Wellen
University of Pennsylvania
June 7, 2018
Roles of acetyl-CoA metabolism in gene regulation and tumorigenesis
Xin Chen
Johns Hopkins University
November 1, 2018
Asymmetry from Symmetry or Symmetry from Asymmetry?
Houra Merrikh
Vanderbilt University
February 7, 2019
Replication-transcription conflicts and evolutionary mechanisms of antimicrobial resistance
Satchidananda Panda
The Salk Institute
March 7, 2019
Circadian rhythm and time-restricted eating for the prevention and treatment of chronic diseases
Chi Dang
The Wistar Institute
April 4, 2019
MYC, metabolism and clock disruption
Jan Lammerding
Cornell University
May 2, 2019
Nuclear mechanobiology in cancer cell migration
Alberto Ciccia
Columbia University
June 6, 2019
Regulation of genome stability by replication fork processing

2007 to 2009 Lecture Series

Simon Boulton
London Research Institute, Cancer UK
October 24, 2007
Repairing DNA damage in S-phase
Roel Nusse
Stanford University, School of Medicine
November 28, 2007
Wnt proteins as self-renewing factors for various stem cells
Jan Michael Peters
IMP – Research Institute of Molecular Pathology
January 23, 2008
How cohesin controls sister chromatid cohesion and transcription
Marco Foiani
IFOM – F.I.R.C. Institute of Molecular Oncology
February 27, 2008
Mechanisms preserving the integrity of replicating chromosomes
Scott Lowe
Cold Spring Harbor Laboratory
March 26, 2008
Tumor Suppression
Arshad Desai
Ludwig Institute for Cancer Research
April 23, 2008
Segregating the Genome During Cell Division
Dafna Bar-Sagi
NYU School of Medicine
May 28, 2008
Ras and the cancer cell: A transforming relationship
Andre Nussenzweig
National Cancer Institute, NIH
October 30, 2008
Pathways that maintain genome stability
Celeste Simon
University of Pennsylvania School of Medicine
December 4, 2008
HIFs, Stem Cells, and Tumor Progression
Elena Conti
Max Planck Institute for Biochemistry
January 29, 2009
Molecular mechanisms of RNA degradation
David Pellman
Dana-Farber Cancer Institute
February 26, 2009
Polyploidy, Aneuploidy and Cancer
Andrea Musacchio
FIRC Institute of Molecular Oncology Foundatio-European Institute of Oncology
March 26, 2009
The molecular basis of cell division
Frank Uhlmann
London Research Institute, Cancer Research UK
May 7, 2009
The irreversibility of cell cycle transitions: Why the clock never turns back
Sue Biggins
Fred Hutchinson Cancer Research Center
June 25, 2009
Regulation of Chromosome Segregation
Steve Artandi
Stanford University Medical Center
October 1, 2009
Telomerase, cancer and Wnt signaling
Kerry Bloom
University of North Carolina at Chapel Hill
November 5, 2009
Springs and struts in the Mitotic spindle
Fred Alt
Harvard Medical School
December 3, 2009
Mechanisms that promote and suppress translocations in B lymphocytes
Angelika Amon
Massachusetts Institute of Technology
February 4, 2010
Causes and consequences of aneuploidy
David Livingston
Dana-Farber Cancer Institute
March 4, 2010
Unexpected insights into the regulation of BRCA1 function
Richard Treisman
London Research Institute, Cancer Research UK
April 1, 2010
SRF – linking transcription to cytoskeletal dynamics