News & HighlightsNews
Researchers create map of “shortcuts” between all human genes
...Giles lab, headed by Jean-Laurent Casanova, previously showed that children with HSE have mutations in TLR3 or in genes that are closely functionally related to TLR3. In other words, these genes are located at a short biological distance from TLR3. As a result, novel herpe...
Mutations in a single gene underlie vulnerability to two unrelated types of infections
...For the last 20 years, Rockefeller’s Jean-Laurent Casanova, professor, head of the St. Giles Laboratory of Human Genetics and Infectious Disease, Howard Hughes Medical Institute investigator, and a senior attending physician at The Rockefeller University Hospital, has soug...
Brain displays an intrinsic mechanism for fighting infection
...The lab, headed by Jean-Laurent Casanova, collaborated with scientists at Harvard Medical School and Memorial Sloan-Kettering Cancer Institute to create induced pluripotent stem cells. Made from the patients’ own tissue, the stem cells were developed into central nervous s...
Scientists pinpoint source of recurrent yeast infections in autoimmune syndrome
...In 33 patients with the ailment, known as autoimmune polyendocrine syndrome, or APS-1, researchers led by Jean-Laurent Casanova, head of the Laboratory of Human Genetics of Infectious Diseases, found antibodies that attack a class of immune proteins called cytokines. Altho...
Nature Genetics: December 11, 2011
Nature Genetics online: December 11, 2011 Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome Carine Le Goff, Clémentine Mahaut, Avinash Abhyankar, Wilfried Le Goff, Valérie Serre, Alexandra Afenjar, Anne Destrée, Maja di Rocco, Delphine Héron, Sébastien Jacquemon...
Nature Immunology: December 25, 2011
...Diaz, J Magarian Blander, Claire-Michèle Farber, Guido Silvestri, Charlotte Cunningham-Rundles, Michaela Calvillo, Carlo Dufour, Lucia Dora Notarangelo, Vassilios Lougaris, Alessandro Plebani, Jean-Laurent Casanova, Stephanie C. Ganal, Andreas Diefenbach, Juan Ignacio Arós...
Protein proves vital in immune response to bacteria
...But the lab, headed by Senior Attending Physician Jean-Laurent Casanova, tapped into their database of 300 people with what’s known as Mendelian susceptibility to mycobacterial disease, a rare disorder that predisposes individuals to become severely ill from exposure to my...
Genetic epidemiologist named visiting professor
Laurent Abel, a geneticist interested in infectious diseases, has been appointed a visiting professor and member ofJean-Laurent Casanova’s Laboratory of Human Genetics of Infectious Disease. Though he will continue to be based in France — his existing laboratory is at ...
Genetic epidemiologist named visiting professor
ZACH VEILLEUX Laurent Abel, a geneticist interested in infectious diseases, has been appointed a visiting professor and member of Jean-Laurent Casanova’s Laboratory of Human Genetics of Infectious Disease. Though he will continue to be based in France — his existing la...
Charles M. Rice awarded Dautrebande Prize
...Jean-Laurent Casanova, senior attending physician at The Rockefeller University Hospital and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases received the award in 2004 while at the Necker Medical School in Paris.
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