A novel platform for identifying metabolic gene functions has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism.
With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments.
Since first detected in birds in 2021, avian flu has killed millions of poultry and infected animals once thought to be immune. What early warning signs could point to an increasing risk for humans?
New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1.
The advent of AlphaFold3 could be an unprecedented boon for drug development. Computational biologist Jiankun Lyu discusses the pros and cons of the tech, and his work analyzing the algorithm.
The findings in mice may explain how addictive drugs hijack natural reward processing systems, creating the urge to use while throwing natural urges to eat and drink off-kilter.
Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.
uLIPSTIC, an updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.
A novel platform allows researchers to directly target enzymes implicated in infectious diseases, several genetic disorders, and some cancers for the first time.
The end replication problem dictates that telomeres shrink unless telomerase intervenes. But the problem is actually twice as complicated, with telomerase providing only part of the solution.
The absence of a single immune cell receptor has been linked to both fewer defenses against mycobacterial infections, such as TB, and damaging buildup of sticky residue in the lungs.
A class of ineffective immune cells may be driving Alzheimer’s disease, a finding that could both explain why APOE4 gene increases the risk of the disease and why a new drug can impact it.
Luciano Marraffini’s research helped lay the groundwork for the newly FDA-approved CRISPR-based therapy for sickle cell anemia. He reflects on how we got here—and where the science is going next.
