The symptoms of Huntington’s typically appear in middle age, but the disease may in fact originate much earlier. New research shows that a patient’s neural abnormalities may arise already during embryonic development—suggesting that treating the disease early may be beneficial.
With new imaging methods, scientists hope to make significant progress in the fight against obesity. A new report reveals striking images of neural projections within fat tissue, and clues for the development of new drugs.
Scientists studying the cell’s DNA-copying machinery have discovered a molecular mechanism that helps reactivate it should it stop prematurely. Its function may prevent genetic errors like those that cause cancer.
Researchers have found that the cells directing the very first steps of brain formation are not other neurons, as scientists have long assumed. They've also uncovered previously hidden molecular pathways that attract neurons into the brain.
Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
Scientists found that inhibiting a regulatory protein alters the intricate signaling chemistry that is responsible for many of the disease’s symptoms. The findings provide a path to possible therapeutics for disorders associated with Fragile X.
Scientists have found that stem cells in the skin remember an injury, helping them close recurring wounds faster. The discovery could advance research and treatment of psoriasis and other inflammatory diseases.
Scientists have found unexpected differences in how male and female mice respond to stress. Their findings are raising big questions about sex discrepancies in the brain and their impact on neuropsychiatric disease.