New findings provide insights about how the intestine maximizes nutrient uptake, while at the same time protecting the body from potentially dangerous microbes.
Rockefeller scientists have identified a genetic condition that makes people prone to developing tuberculosis. In a British population, they found that the condition underlies one percent of cases of the disease—a finding that may ultimately lead to new treatment options.
Researchers successfully modified immune cells to produce antibodies that fight HIV. This strategy could eventually be used to develop a vaccine against the virus, among other conditions.
Increasingly, bacteria do not succumb to antibiotics. Rockefeller researchers have developed a new class of antimicrobial drug, lysin, with one compound showing promising results in a clinical trial—suggesting that an alternative to antibiotics may be on the horizon.
Geckos are amazingly agile. In addition to running across land and up trees, the animals can prance across the surface of water. A new study reveals how they do it.
Using gene editing technology, researchers have developed a new way to study B cell activation in mice. This technique makes research more efficient, and has the potential to improve our understanding of immune responses in humans.
Researchers have uncovered the genetic factors that make some people susceptible to Whipple's disease, an intestinal inflammatory disorder that causes diarrhea, pain, and weight loss.
Maimon, who studies cognition and decision-making, and Marraffini, who studies the bacterial defense system CRISPR-Cas, are among 19 scientists nationwide to receive this designation.
Ravetch receives the award for his groundbreaking work analyzing the immune system’s antibody response. He has worked for decades on the Fc fragment of the antibody molecule and its binding partners, known as Fc receptors.
Scientists have developed a new strategy to study the cells that host hidden reserves of dormant HIV, a step that may lead to new treatments that go beyond controlling the infection and instead aim to eradicate the virus entirely.
Among other superpowers, stem cells have a knack for fending off viruses like dengue and zika. Scientists have gained new insight into these curious defense strategies—knowledge they say could fuel the development of drugs against a range of diseases.
The gateway to cellular headquarters has 552 components. A new map that shows how all these pieces fit together could help scientists study numerous diseases.
A new report details three cases of secondary brain tumors in people with fibrolamellar hepatocellular carcinoma. The researchers say imaging tests could improve treatment for patients whose cancer spreads to the brain from the liver.
In mining soil for natural drugs, scientists have discovered a brand-new antibiotic potent against many bacteria. They hope it could be used to treat infections that cannot be stopped with existing drugs.
New research has helped explain what goes wrong in Aicardi-Goutières syndrome, a rare brain disorder. Patients with the disease have genetic abnormalities that may put their cells at risk of accidentally triggering an antiviral response.
Virtually all aspects of life and disease depend of brief exchanges between cells. A new technique to study cell-to-cell contacts lets interacting cells “smear” one another with the biological equivalent of lipstick.
A new treatment may help cancer patients who don't respond to traditional immunotherapy. Findings from the first-ever clinical trial reveal that it is effective in activating immune cells that kill cancer cells.
New research shows that subtle differences between bacterial strains may cause dramatic differences in outcome between people infected with the same microbe.
Scientists found that immune cells called intraepithelial lymphocytes act as a surveillance force at the intestine, helping to generate an appropriate immune response to both friendly bacteria and dangerous pathogens.
Nussenzweig was honored at a ceremony today at the Institut Pasteur in Paris.The award recognizes investigators for past or ongoing work demonstrating real scientific progress in the life sciences.
Scientists have engineered a mouse model to study a rare and often-fatal form of liver cancer. They’ve used it to clarify what drives these tumors at the molecular level, and discover new drug concepts.
Scientists have discovered a peculiarity in the genetic code of HIV that might explain how this and other viruses evolved ways to dodge our immune system. The findings could make it possible to develop safer vaccines.
Scientists have identified a protein that many viruses require to spread within a host—a discovery that could lead to fighting diseases as varied as parainfluenza, West Nile, and Zika with a single drug. This finding could also lead to the development of treatments for emerging viruses.
One of the most prestigious funding programs in the world, the MacArthur fellows program awards grants to exceptionally creative individuals as an investment in their potential.
Scientists have found unexpected differences in how male and female mice respond to stress. Their findings are raising big questions about sex discrepancies in the brain and their impact on neuropsychiatric disease.
To keep up with evasive flu viruses, new vaccines must be developed each year. Scientists are devising a strategy to better prevent the disease without annual shots.
