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Michel C. Nussenzweig honored with the 2016 Robert Koch Award

Michel C. Nussenzweig, Zanvil A. Cohn and Ralph M. Steinman Professor and head of the Laboratory of Molecular Immunology, has won the 2016 Robert Koch Award. Nussenzweig will share the €100,000 prize, given by the Robert Koch Foundation of Germany, with Alberto Mantovani from Humanitas University...

Researchers uncover how “silent” genetic changes drive cancer

At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA. “We’ve long thought of these molecules as little more than middle men participating in the process of translating proteins...

35 labs and counting: How the Robertson Therapeutic Development Fund speeds translational research at Rockefeller

by Alexandra MacWade, assistant editor Developing a new medical product is a complex, high-risk endeavor. Of the thousands of clinically promising concepts scientists formulate each year, only a small fraction move beyond the lab. The Robertson TDF was created to advance work that has gone beyon...

Scientists find evidence that cancer can arise from changes in the proteins that package DNA

A mutation that affects the proteins that package DNA—without changing the DNA itself—can cause a rare form of cancer, according to new findings in this week’s Science from researchers at Rockefeller University. The mutation is present in histones, the protein scaffolding around which DNA w...

C. David Allis receives the 2016 Gruber Genetics Prize

C. David Allis, Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics, has won the 2016 Gruber Genetics Prize. He shares the $500,000 award with Michael Grunstein of the University of California, Los Angeles. The award, given by The Gruber Foundation, reco...

Antibody therapy opens door to potential new treatment for HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades. But this therapy has drawbacks...

In the News - The New Yorker - Allis

Same but Different: How epigenetics can blur the line between nature and nurture "Allis walked me to his lab, a fluorescent-lit space overlooking the East River, divided by wide, polished-stone benches. A mechanical stirrer, whirring in a corner, clinked on the edge of a glass beaker. 'Two featur...

Mice engineered with rare kidney disease provide new insights about how cells repair broken DNA

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell—sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have ...

Awards, arrivals, and promotions

Congratulations to our latest award winners: Cori Bargmann has won the 2016 Edward M. Scolnick Prize in Neuroscience, an award given by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field. She is being honored for her work on the genetic and neural mech...

New research clarifies how stem cells get activated to produce new hair—and what happens when their regenerative powers wear out

Adult stem cells provide the body with a reservoir from which damaged or used up tissues can be replenished. In organs like the intestines and skin, which need constant rejuvenating, these stem cells are dividing frequently. But in other body structures, including the hair follicles, they are hel...