Experimental Design

To call in the statistician after the experiment is done may be no more than asking him to perform a post-mortem examination: he may be able to say what the experiment died of.
Ronald Fisher

The Bioinformatics team provides advice on experimental design and analysis planning at all stages of an experiment. Working with the experimentalist(s) alongside Proteomics and/or Genomics facilities at early stages in the design allow for the Bioinformatics core to assist in the construction of appropriate experimental designs and to ensure the desired power may be achieved.

Examples of typical experimental design tasks:
Power calculations for RNA-seq.
Design for differential ATAC-seq analysis..
Choice of sequencing parameters for differential splicing analysis.