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Displaying 87 of 2722 articles.

The genetic underpinnings of severe staph infections

...Rockefeller immunologist Jean-Laurent Casanova examined the protein-coding genomes of more than 100 patients who had suffered from unexplained severe staph infections. The common genetic thread linking some of th...

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Missing immune molecule may explain why some HPV patients sprout giant horn-like growths

...How could one virus provoke such a severe reaction in a select few, but leave most people symptom-free? In a new study published in Cell, Rockefeller’s Jean-Laurent Casanova answers this question by examining the genetics of an otherwise healthy patient who contracted a severe case of tree-man syn...

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The common thread in severe COVID-19 

...Two papers from the laboratory of Jean-Laurent Casanova previously demonstrated that at least 10 percent of severe cases can be chalked up to either a genetic condition that cripples IFN production, or misguided antibodies that attack those crucial proteins. Now, two new studies in Science...

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How one patient’s rare mutation helped solve a mycobacterial mystery

...The lab of Jean-Laurent Casanova, which has spent 25 years studying the interplay between human genes and mycobacterial disease, continues to uncover the genetic defects that separate those who develop serious infections from those who remain symptomless after being exposed to mycobacteria. Their la...

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has won the 2016 Inserm Grand Prix for his work on the genetic basis of infectious diseases. The prestigious award, given annually by Inserm—the French National Institute of Health and M...

Jean-Laurent Casanova honored with the Korsmeyer Award

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, is the recipient of the 2016 Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award, given by the American Society for Clinical...

Jean-Laurent Casanova elected to the National Academy of Medicine

Jean-Laurent Casanova, who investigates genetic vulnerability to infectious diseases among children, has been elected to the U.S. National Academy of Medicine, the health and medicine arm of the National Academy of Sciences. Casanova is professor and head of the St. Giles Laboratory of Human Gen...

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

...These findings provide compelling evidence that the disruption of type I interferon is often the cause of life-threatening COVID-19,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University and a Howard Hughes Medical I...

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

...We may find a genetic clue that could help explain what is driving this severe complication in these children, which can in turn inform their clinical care,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University. A...

Llamas immune to coronavirus, what zebrafish are thinking, and other memorable science stories of 2020 

...Shortly thereafter, Jean-Laurent Casanova and colleagues made headlines with two reports revealing that people with the most severe cases of the disease frequently lack interferon I, a cluster of proteins that repel viruses, providing the first molecular explanation for why some young, otherwi...

Recent Awards and Honors

Tomasz Ahrends and Kevin Gonzales receive Tri-Institutional Breakout Awards

June 2, 2022

Tomasz Ahrends, from Daniel Mucida’s lab, and Kevin Gonzales, from Elaine Fuchs’s lab, are recognized for their respective postdoctoral work.

Leslie B. Vosshall

Leslie B. Vosshall named a member of the American Philosophical Society

June 1, 2022

Vosshall is honored for her investigation of how sensory stimuli are perceived and processed.

More awards and honors

Rockefeller in the News

The Washington Post

“What we are looking for is potentially very rare genetic variants with a very big impact on the individual,” said András Spaan, a clinical microbiologist and fellow at the Rockefeller University in New York who is spearheading a search for genetic material responsible for coronavirus resistance.    

Science News

Michel Nussenzweig and colleagues examined what happens to the immune response after a third dose of vaccine, focusing especially on very long-lived immune cells called memory B cells. Those memory cells still made new antibodies when they got a third look at the vaccine.

Nature

Erich Jarvis says he wants the Human Pangenome Project to achieve a better representation of human genetic diversity. “I’m a person of colour. I grew up as an African American. I grew up as an under-represented minority in the sciences,” he says. “My diversity is not represented. So I have a personal motivation and a societal one to make sure that this pangenome really represents populations.”      

Seek magazine

Rockefeller’s flagship publication is interested not just in scientific results, but in the people, ideas, and conversations that ignite discovery. The latest issue explores how stem cells help our bodies form, develop, and heal—and how they’re powering a new surge in science. Also: Do flies ever get lonely? And much more.


From this issue

 


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