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Displaying 83 of 2614 articles.

Llamas immune to coronavirus, what zebrafish are thinking, and other memorable science stories of 2020 

...Shortly thereafter, Jean-Laurent Casanova and colleagues made headlines with two reports revealing that people with the most severe cases of the disease frequently lack interferon I, a cluster of proteins that repel viruses, providing the first molecular explanation for why some young, otherwi...

Scientists trace severe COVID-19 to faulty genes and autoimmune condition

...These findings provide compelling evidence that the disruption of type I interferon is often the cause of life-threatening COVID-19,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University and a Howard Hughes Medical I...

Rockefeller scientists investigate life-threatening inflammation affecting children with COVID-19

...We may find a genetic clue that could help explain what is driving this severe complication in these children, which can in turn inform their clinical care,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University. A...

The gene hunt to explain why some young, healthy people die from COVID-19

...Infectious diseases are always an interplay between a pathogen and the host’s immunity,” says Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at The Rockefeller University. “At least some of these patients may suffer from a genetic variation ...

Patient with unusually severe infection leads scientists to a rare type of immune deficiency

...An unexpected life-threatening infectious disease that is not explained by a compromised immune system often turns out to be a genetic disorder,” says lead investigator Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases at Rockefeller University. ...

Jean-Laurent Casanova receives the 2016 Inserm Grand Prix

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, has won the 2016 Inserm Grand Prix for his work on the genetic basis of infectious diseases. The prestigious award, given annually by Inserm—the French National Institute of Health and M...

Jean-Laurent Casanova honored with the Korsmeyer Award

Jean-Laurent Casanova, professor and head of the St. Giles Laboratory of Human Genetics of Infectious Diseases, is the recipient of the 2016 Stanley J. Korsmeyer Award for his work investigating the genetic basis of pediatric infectious diseases. The award, given by the American Society for Clinical...

Study pinpoints rare genetic change that may boost risk of HPV-related illness

...We’ve cracked the enigma of why the boys developed these warts,” says lead investigator Jean-Laurent Casanova, head of the St. Giles Laboratory of Human Genetics of Infectious Diseases. The findings add to a growing body of evidence that is changing how researchers think about infectious d...

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Researchers find genetic link to tuberculosis

...Now, Rockefeller scientist Jean-Laurent Casanova has identified a genetic condition that makes the immune system susceptible to mycobacterial attack. Last year, Casanova showed that the risk of developing TB is heightened in people who have two copies of a particular variation of the gene coding ...

Jean-Laurent Casanova elected to the National Academy of Medicine

Jean-Laurent Casanova, who investigates genetic vulnerability to infectious diseases among children, has been elected to the U.S. National Academy of Medicine, the health and medicine arm of the National Academy of Sciences. Casanova is professor and head of the St. Giles Laboratory of Human Gen...

Recent Awards and Honors

Junyue Cao

Junyue Cao wins Science & SciLifeLab Grand Prize For Young Scientists

November 19, 2020

Cao is recognized for his work using single-cell genomic methods to enable developmental mapping of entire organisms, described in an essay published in Science.
LLuciano Marraffini portrait

Luciano Marraffini awarded Max Planck-Humboldt Medal

October 14, 2020

Marraffini receives the award for his achievements studying CRISPR-Cas, a bacterial immune mechanism whose discovery led to modern gene-editing tools.
More awards and honors

Rockefeller in the News

The New York Times

Laboratory studies from Michel Nussenzweig and others of mutations circulating in South Africa suggest they may dodge some of the body’s immune responses.

The Wall Street Journal

Researchers are working on new antibody drugs that can be given with quick jabs in the arm, similar to flu shots. They would enable patients to get treated quickly after being diagnosed with Covid-19, said Michel C. Nussenzweig, an immunologist and professor at Rockefeller University in New York.

Nature News

Evidence from Jean-Laurent Casanova and others is growing that self-attacking ‘autoantibodies’ could be the key to understanding some of the worst cases of SARS-CoV-2 infection.

Seek magazine

Rockefeller’s flagship publication is interested not just in scientific results, but in the people, ideas, and conversations that ignite discovery. The latest issue takes us inside the response to the pandemic, where scientists are using every tool in the 21st century playbook to transform COVID-19 into a manageable disease. Also: Mosquito menace, The brain inside your gut, and Addiction then and now.


From this issue

 


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